PIMA549139
Connexin 43 Recombinant Rabbit Monoclonal Antibody (PSH0-32), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA549139-Each-of-1 | In Stock | ₹ 38,074.20 |
PIMA549139 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,074.20
GST (18%): ₹ 6,853.356
Total Price: ₹ 44,927.556
Antigen
Connexin 43
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P08050, P17302, P23242
Gene Symbols
GJA1
Immunogen
Recombinant protein within human connexin 43 aa 219-382.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
PSH0-32
Conjugate
Unconjugated
Gene
GJA1
Gene Alias
alpha 1 connexin; AU042049; AVSD3; AW546267; CMDR; Cnx43; connexin 43; connexin43; connexin-43; cx43; Cx-43; cx43 protein; cx43a1; Cx43alpha1; CXA1; Cxn-43; DFNB38; EKVP; etID309742.9; gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein; gap junction membrane channel protein alpha 1; gap junction protein; gap junction protein alpha 1; gap junction protein connexin 43; gap junction protein, alpha 1; gap junction protein, alpha 1, 43 kD (connexin 43); gap junction protein, alpha 1, 43kDa; gap junction protein, alpha 1, 43kDa (connexin 43); gja1; Gja-1; GJAL; HLHS1; HSS; Npm1; ODD; ODDD; ODOD; PPKCA; SDTY3; shf; Short fin protein; sof; stopsel; stp; Syndactyly type III; vascular smooth muscle connexin43; Vascular smooth muscle connexin-43; zfCx43.3
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
14609, 24392, 2697
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Sequence Similarities: 95% Mouse/Rat Tissue Specificity: Expressed in the heart and fetal cochlea
- Positive Control: A549 cell lysate, PC-12 cell lysate, mouse heart lysate, human heart tissue, human testis tissue
- Subcellular location: Plasma membrane
- Endoplasmic reticulum
- Cell junction, gap junction
- Connexin 43 (Cx43) is a member of the gap junction protein family
- Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels
- Clusters of these channels assemble to make gap junctions
- Gap junction communication is important in development and regulation of cell growth
- Phosphorylation of Cx43 is important in regulating assembly and function of gap junctions
- Ser368 of Cx43 is phosphorylated by protein kinase C (PKC) after activation by phorbol esters, which decreases cell-to-cell communication
- Src can interact with and phosphorylate Cx43 to alter gap junction communication
- GFAP are membrane-spanning proteins that facilitate the transfer of ions and small molecules between cells
- According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta
- Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development
- Connexin 43 is also targeted by several protein kinases that regulate myocardial cell-cell coupling
- A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5
- Mutations in the GFAP gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy, oculodentodigital dysplasia and heart malformations
- Alternatively spliced transcript variants of GFAP have been found.
Compare Similar Items
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Antigen: Connexin 43
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P08050, P17302, P23242
Gene Symbols: GJA1
Immunogen: Recombinant protein within human connexin 43 aa 219-382.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: PSH0-32
Conjugate: Unconjugated
Gene: GJA1
Gene Alias: alpha 1 connexin; AU042049; AVSD3; AW546267; CMDR; Cnx43; connexin 43; connexin43; connexin-43; cx43; Cx-43; cx43 protein; cx43a1; Cx43alpha1; CXA1; Cxn-43; DFNB38; EKVP; etID309742.9; gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein; gap junction membrane channel protein alpha 1; gap junction protein; gap junction protein alpha 1; gap junction protein connexin 43; gap junction protein, alpha 1; gap junction protein, alpha 1, 43 kD (connexin 43); gap junction protein, alpha 1, 43kDa; gap junction protein, alpha 1, 43kDa (connexin 43); gja1; Gja-1; GJAL; HLHS1; HSS; Npm1; ODD; ODDD; ODOD; PPKCA; SDTY3; shf; Short fin protein; sof; stopsel; stp; Syndactyly type III; vascular smooth muscle connexin43; Vascular smooth muscle connexin-43; zfCx43.3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14609, 24392, 2697
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
Connexin 43
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P08050, P17302, P23242
Gene Symbols:
GJA1
Immunogen:
Recombinant protein within human connexin 43 aa 219-382.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
PSH0-32
Conjugate:
Unconjugated
Gene:
GJA1
Gene Alias:
alpha 1 connexin; AU042049; AVSD3; AW546267; CMDR; Cnx43; connexin 43; connexin43; connexin-43; cx43; Cx-43; cx43 protein; cx43a1; Cx43alpha1; CXA1; Cxn-43; DFNB38; EKVP; etID309742.9; gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein; gap junction membrane channel protein alpha 1; gap junction protein; gap junction protein alpha 1; gap junction protein connexin 43; gap junction protein, alpha 1; gap junction protein, alpha 1, 43 kD (connexin 43); gap junction protein, alpha 1, 43kDa; gap junction protein, alpha 1, 43kDa (connexin 43); gja1; Gja-1; GJAL; HLHS1; HSS; Npm1; ODD; ODDD; ODOD; PPKCA; SDTY3; shf; Short fin protein; sof; stopsel; stp; Syndactyly type III; vascular smooth muscle connexin43; Vascular smooth muscle connexin-43; zfCx43.3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14609, 24392, 2697
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: RAB8A
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P35280, P55258, P61006
Gene Symbols: RAB8A
Immunogen: Synthetic peptide within human rab8a aa 151-200/207.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: JE64-79
Conjugate: Unconjugated
Gene: RAB8A
Gene Alias: AA409338; cell line NK14 derived transforming oncogene; MEL; mel transforming oncogene (derived from cell line NK14); mel transforming oncogene (derived from cell line NK14)- RAB8 homolog; mel transforming oncogene (RAB8 homolog); oncogene c-mel; Rab8; Rab8a; RAB8A, member RAS oncogene family; ras-associated protein RAB8; ras-related protein Rab-8A
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 117103, 17274, 4218
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
RAB8A
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P35280, P55258, P61006
Gene Symbols:
RAB8A
Immunogen:
Synthetic peptide within human rab8a aa 151-200/207.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
JE64-79
Conjugate:
Unconjugated
Gene:
RAB8A
Gene Alias:
AA409338; cell line NK14 derived transforming oncogene; MEL; mel transforming oncogene (derived from cell line NK14); mel transforming oncogene (derived from cell line NK14)- RAB8 homolog; mel transforming oncogene (RAB8 homolog); oncogene c-mel; Rab8; Rab8a; RAB8A, member RAS oncogene family; ras-associated protein RAB8; ras-related protein Rab-8A
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
117103, 17274, 4218
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: TMIGD2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q96BF3
Gene Symbols: TMIGD2
Immunogen: The extracellular domain of human TMIGD2.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone: 7A10
Conjugate: Unconjugated
Gene: TMIGD2
Gene Alias: CD28 homolog; CD28 homologue; CD28H; IGPR1; IGPR-1; Immunoglobulin and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor-1; TMIGD2; transmembrane and immunoglobulin domain containing 2; transmembrane and immunoglobulin domain-containing protein 2; transmembrane and immunoglobulin domain-containing protein 2 variant 2; transmembrane and immunoglobulin domain-containing protein 2 variant 3; UNQ3059/PRO9879
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 126259
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
TMIGD2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q96BF3
Gene Symbols:
TMIGD2
Immunogen:
The extracellular domain of human TMIGD2.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone:
7A10
Conjugate:
Unconjugated
Gene:
TMIGD2
Gene Alias:
CD28 homolog; CD28 homologue; CD28H; IGPR1; IGPR-1; Immunoglobulin and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor-1; TMIGD2; transmembrane and immunoglobulin domain containing 2; transmembrane and immunoglobulin domain-containing protein 2; transmembrane and immunoglobulin domain-containing protein 2 variant 2; transmembrane and immunoglobulin domain-containing protein 2 variant 3; UNQ3059/PRO9879
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
126259
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ
Antigen: CBS
Classification: Monoclonal
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and no preservative
Gene Accession No.: P32232, P35520, Q91WT9
Gene Symbols: CBS
Immunogen: E.coli-derived human CBS recombinant protein (Position: K102-E342).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Lyophilized
Applications: Flow Cytometry, Western Blot
Clone: 5B5D7
Conjugate: Unconjugated
Gene: CBS
Gene Alias: AI047524; AI303044; Beta-thionase; Cbs; CBSL; cystathionine beta synthase; cystathionine beta-synthase; cystathionine beta-synthase; LOW QUALITY PROTEIN: cystathionine beta-synthase; Cystathionine beta-synthase-like protein; cystathionine-beta-synthase; hemoprotein H-450; HIP4; LOC100057612; methylcysteine synthase; serine sulfhydrase
Host Species: Mouse
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12411, 24250, 875
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1
Antigen:
CBS
Classification:
Monoclonal
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and no preservative
Gene Accession No.:
P32232, P35520, Q91WT9
Gene Symbols:
CBS
Immunogen:
E.coli-derived human CBS recombinant protein (Position: K102-E342).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Lyophilized
Applications:
Flow Cytometry, Western Blot
Clone:
5B5D7
Conjugate:
Unconjugated
Gene:
CBS
Gene Alias:
AI047524; AI303044; Beta-thionase; Cbs; CBSL; cystathionine beta synthase; cystathionine beta-synthase; cystathionine beta-synthase; LOW QUALITY PROTEIN: cystathionine beta-synthase; Cystathionine beta-synthase-like protein; cystathionine-beta-synthase; hemoprotein H-450; HIP4; LOC100057612; methylcysteine synthase; serine sulfhydrase
Host Species:
Mouse
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12411, 24250, 875
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1