PIMA549174

IFI16 Monoclonal Antibody (2I3D7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA549174-Each-of-1 In Stock ₹ 34,908.48

PIMA549174 - Each of 1

₹ 34,908.48

In Stock

Quantity

1

Base Price: ₹ 34,908.48

GST (18%): ₹ 6,283.526

Total Price: ₹ 41,192.006

Antigen

IFI16

Classification

Monoclonal

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and no preservative

Gene Accession No.

Q16666

Gene Symbols

IFI16

Immunogen

E.coli-derived human IFI16 recombinant protein (Position: E183-K743).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Clone

2I3D7

Conjugate

Unconjugated

Gene

IFI16

Gene Alias

gamma-interferon-inducible protein 16; IFI 16C; IFI16; Ifi-16; IFNGIP1; interferon gamma inducible protein 16; interferon, gamma-inducible protein 16; interferon-gamma induced protein IFI 16; interferon-inducible myeloid differentiation transcriptional activator; PYHIN2

Host Species

Mouse

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3428

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2b

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Description

  • Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
  • IFI16 (gamma-inteferon-inducible protein 16) binds double-stranded DNA
  • It binds preferentially to supercoiled DNA and cruciform DNA structures
  • It seems to be involved in transcriptional regulation and as a transcriptional repressor
  • IFI16 may have a role in the regulation of hematopoietic differentiation through activation of unknown target genes
  • It controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein
  • IFI16 is also involved in innate immune response by recognizing viral dsDNA in the cytosol and nucleus
  • After binding to viral DNA in the cytoplasm, IFI16 recruits TMEM173/STING and mediates the induction of IFN-beta
  • It is necessary to activate the IFR3 signaling cascade suring human herpes simplex virus 1 infection and promotes the assembly of heterochromatin on herpesviral DNA and inhibiton of viral immediate-early gene expression and replication
  • IFI16 is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

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Img

Thermo Scientific

PIMA549174

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Antigen:
IFI16

Classification:
Monoclonal

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
Q16666

Gene Symbols:
IFI16

Immunogen:
E.coli-derived human IFI16 recombinant protein (Position: E183-K743).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
2I3D7

Conjugate:
Unconjugated

Gene:
IFI16

Gene Alias:
gamma-interferon-inducible protein 16; IFI 16C; IFI16; Ifi-16; IFNGIP1; interferon gamma inducible protein 16; interferon, gamma-inducible protein 16; interferon-gamma induced protein IFI 16; interferon-inducible myeloid differentiation transcriptional activator; PYHIN2

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3428

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

PIMA549175

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Antigen:
GNAQ

Classification:
Monoclonal

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P21279, P50148, P82471

Gene Symbols:
GNAQ

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human GNAQ (102-138aa KYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWND).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Form:
Lyophilized

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
13H4

Conjugate:
Unconjugated

Gene:
GNAQ

Gene Alias:
1110005L02Rik; 6230401I02Rik; AA408290; AW060788; CMC1; Dsk1; Dsk10; G alpha q; G protein subunit alpha q; Galpha q; Galphaq; G-ALPHA-q; GAQ; GNAQ; gnaqa; Gq; GqI; guanine nucleotide binding protein (G protein), q polypeptide; guanine nucleotide binding protein alpha q subunit; guanine nucleotide binding protein, alpha q polypeptide; guanine nucleotide regulatory protein G alpha q; guanine nucleotide-binding protein alpha-q; Guanine nucleotide-binding protein G(q) subunit alpha; heterotrimeric guanine nucleotide-binding protein alpha q subunit; si:ch73-270f14.2; SWS

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14682, 2776, 81666

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

PIMA549177

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Antigen:
Optineurin

Classification:
Monoclonal

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q8K3K8, Q8R5M4, Q96CV9

Gene Symbols:
OPTN

Immunogen:
E.coli-derived human Optineurin recombinant protein (Position: R241-I577).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Lyophilized

Applications:
Flow Cytometry, Western Blot

Clone:
3D8

Conjugate:
Unconjugated

Gene:
OPTN

Gene Alias:
14.7K-interacting protein 2; 4930441O07Rik; Ag9 C5; ALS12; E3-14.7K-interacting protein; FIP 2; FIP2; FIP-2; FIP-2-like protein; GLC1E; HIP 7; HIP7; HIP-7; Huntingtin interacting protein L; huntingtin yeast partner L; Huntingtin-interacting protein 7; huntingtin-interacting protein L; HYPL; NEMO-related protein; NRP; Optic neuropathy-inducing protein; optineurin; Optn; TFIIIA IntP; TFIIIA-IntP; transcription factor IIIA-interacting protein; transcrption factor IIIA-interacting protein; tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains; Uban

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10133, 246294, 71648

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

PIMA549178

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Antigen:
SF1

Classification:
Monoclonal

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
Q15637, Q64213

Gene Symbols:
SF1

Immunogen:
E. coli-derived human splicing factor 1 recombinant protein (Position: R160-Q266).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
7D9E3

Conjugate:
Unconjugated

Gene:
SF1

Gene Alias:
BBP; D11S636; M ZFM1; Mammalian branch point-binding protein; MBBP; MZFM; SF; SF1; Splicing factor 1; transcription factor ZFM1; WBP4; wu:fc09f06; ZCCHC25; ZFM1; Zfp162; Zinc finger gene in MEN1 locus; zinc finger protein 162; ZNF162

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117855, 22668, 7536

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b