PIMA549210

Ataxin 1 Monoclonal Antibody (2B13G8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA549210-Each-of-1 In Stock ₹ 34,908.48

PIMA549210 - Each of 1

₹ 34,908.48

In Stock

Quantity

1

Base Price: ₹ 34,908.48

GST (18%): ₹ 6,283.526

Total Price: ₹ 41,192.006

Antigen

Ataxin 1

Classification

Monoclonal

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and no preservative

Gene Accession No.

P54253, P54254, Q63540

Gene Symbols

ATXN1

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Ataxin 1(778-808aa ESRKLEKSEDEPPLTLPKPSLIPQEVKICIE).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Lyophilized

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

2B13G8

Conjugate

Unconjugated

Gene

ATXN1

Gene Alias

2900016G23Rik; alternative ataxin1; ataxin 1; Ataxin1; ataxin-1; Atx1; Atx-1; Atx-1-PB; Atxn1; C85907; CG4547; CG4547-PB; D6S504E; dAtx-1; Dmel\CG4547; Dmel_CG4547; ENSMUSG00000074917; Gm10786; OTTHUMP00000016065; SCA1; spinocerebellar ataxia 1; spinocerebellar ataxia 1 homolog; spinocerebellar ataxia type 1 protein; Spinocerebellar ataxia type 1 protein homolog

Host Species

Mouse

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20238, 25049, 6310

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2b

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Description

  • Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
  • Immunogen sequence is different from the related and rat sequences by one amino acid
  • The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord
  • Clinically, ADCA has been divided into three groups: ADCA types I-III
  • ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes
  • ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders
  • Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions
  • ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein
  • The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations
  • The function of the ataxins is not known
  • This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1)
  • At least two transcript variants encoding the same protein have been found for this gene.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA549210

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Antigen:
Ataxin 1

Classification:
Monoclonal

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
P54253, P54254, Q63540

Gene Symbols:
ATXN1

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Ataxin 1(778-808aa ESRKLEKSEDEPPLTLPKPSLIPQEVKICIE).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Lyophilized

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
2B13G8

Conjugate:
Unconjugated

Gene:
ATXN1

Gene Alias:
2900016G23Rik; alternative ataxin1; ataxin 1; Ataxin1; ataxin-1; Atx1; Atx-1; Atx-1-PB; Atxn1; C85907; CG4547; CG4547-PB; D6S504E; dAtx-1; Dmel\CG4547; Dmel_CG4547; ENSMUSG00000074917; Gm10786; OTTHUMP00000016065; SCA1; spinocerebellar ataxia 1; spinocerebellar ataxia 1 homolog; spinocerebellar ataxia type 1 protein; Spinocerebellar ataxia type 1 protein homolog

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20238, 25049, 6310

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

PIMA549211

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Antigen:
SHIP2

Classification:
Monoclonal

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
O15357, Q6P549, Q9WVR3

Gene Symbols:
INPPL1

Immunogen:
E. coli-derived human INPPL1 recombinant protein (Position: R1172-K1258).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
8C13

Conjugate:
Unconjugated

Gene:
INPPL1

Gene Alias:
51C; 51C protein; ablSH3-binding protein; inositol polyphosphate phosphatase like 1; inositol polyphosphate phosphatase-like 1; inositol polyphosphate phosphatase-like protein 1; Inppl1; INPPL-1; OPSMD; Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2; protein 51C; SH2 domain-containing inositol 5'-phosphatase 2; SH2 domain-containing inositol phosphatase 2; SH2 domain-containing inositol-5'-phosphatase 2; SH2-containing inositol phosphatase 2; SHIP2; SHIP-2

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16332, 3636, 65038

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a

Img

Thermo Scientific

PIMA549212

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Antigen:
PRDX6

Classification:
Monoclonal

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
O08709, O35244, P30041

Gene Symbols:
PRDX6

Immunogen:
E.coli-derived human Peroxiredoxin 6 recombinant protein (Position: E15-P224).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
6I8

Conjugate:
Unconjugated

Gene:
PRDX6

Gene Alias:
1-Cys; 1-Cys peroxiredoxin; 1-Cys PRX; 1-cysPrx; 24 kDa protein; 9430088D19Rik; AA690119; Acidic calcium-independent phospholipase A2; aiPLA2; Antioxidant protein 2; Aop2; Brp-12; CP-3; epididymis secretory sperm binding protein Li 128m; GPx; HEL-S-128m; KIAA0106; Liver 2D page spot 40; Ltw4; Ltw-4; Lvtw-4; MGC46173; MSP23; NKEFA; Non-selenium glutathione peroxidase; NSGPx; ORF06; p29; PAG; PAGA; PAGB; peroxiredoxin 6; peroxiredoxin-6; Prdx5; Prdx6; PRX; Prx6; Red blood cells page spot 12; thiol-specific antioxidant protein; Tsa

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11758, 94167, 9588

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

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Thermo Scientific

PIMA549214

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Antigen:
HGD

Classification:
Monoclonal

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
Q93099

Gene Symbols:
HGD

Immunogen:
E. coli-derived human HGD recombinant protein (Position: D374-N445).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
2F11E1

Conjugate:
Unconjugated

Gene:
HGD

Gene Alias:
aku; alkaptonuria; HGD; HGO; homogentisate 1, 2-dioxygenase; homogentisate 1,2-dioxygenase; homogentisate oxidase; homogentisate oxygenase; Homogentisic acid oxidase; homogentisicase

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3081

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b