PIPA1027A48

Cyclophilin B Polyclonal Antibody, Alexa Fluor™ 488, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA1027A48-Each-of-1 In Stock ₹ 38,416.44

PIPA1027A48 - Each of 1

₹ 38,416.44

In Stock

Quantity

1

Base Price: ₹ 38,416.44

GST (18%): ₹ 6,914.959

Total Price: ₹ 45,331.399

Antigen

Cyclophilin B

Classification

Polyclonal

Conjugate

Alexa Fluor 488

Gene

PPIB

Gene Alias

AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19035, 478337, 5479, 64367

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Immunocytochemistry

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4

Gene Accession No.

P23284, P24368, P24369

Gene Symbols

PPIB

Immunogen

Synthetic peptide corresponding to residues C(194) G K I E V E K P F A I A K E(208) of human CyPB

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA1027AAY

--

Img

Thermo Scientific

PIPA1027AAZ

--

Img

Thermo Scientific

PIPA11051A4

--

Img

Thermo Scientific

PIPA1860AY

--

Img

Thermo Scientific

PIPA1861AY

--

Img

Thermo Scientific

PIPA1060A48

--

Img

Thermo Scientific

PIPA5100044

--

Img

Thermo Scientific

PIPA5100047

--

Description

  • PA1027AA488 detects cyclophilin B (CyPB) in mouse, rat, canine, and human tissues
  • The PA1027AA488 immunogen is a synthetic peptide corresponding to residues C(194) G K I E V E K P F A I A K E(208) of human CyPB
  • This sequence is almost completely conserved between human, mouse, rat, bovine, and chicken
  • PA1027AA488 immunizing peptide (Cat
  • # PEP-058) is available for use in neutralization and control experiments
  • Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506
  • Proteins which bind FK506 are termed FK506 Binding Proteins (FKBP's) and those which bind cyclosporin A are called cyclophilins (CyP)
  • Both CyP:CsA and FKBP:FK506 complexes have been shown to inhibit calcineurin, a calcium and calmodulin dependent protein phosphatase which has been implicated as an important signaling enzyme in T-cell activation
  • Thus, providing a possible mechanism of immunosuppression by CsA and FK506
  • Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds
  • As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA1027A48

--


Antigen:
Cyclophilin B

Classification:
Polyclonal

Conjugate:
Alexa Fluor 488

Gene:
PPIB

Gene Alias:
AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19035, 478337, 5479, 64367

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P23284, P24368, P24369

Gene Symbols:
PPIB

Immunogen:
Synthetic peptide corresponding to residues C(194) G K I E V E K P F A I A K E(208) of human CyPB

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA1027AAY

--


Antigen:
Cyclophilin B

Classification:
Polyclonal

Conjugate:
Alexa Fluor 647

Gene:
PPIB

Gene Alias:
AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19035, 478337, 5479, 64367

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P23284, P24368, P24369

Gene Symbols:
PPIB

Immunogen:
Synthetic peptide corresponding to residues C(194) G K I E V E K P F A I A K E(208) of human CyPB

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA1027AAZ

--


Antigen:
Cyclophilin B

Classification:
Polyclonal

Conjugate:
Alexa Fluor 555

Gene:
PPIB

Gene Alias:
AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19035, 478337, 5479, 64367

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P23284, P24368, P24369

Gene Symbols:
PPIB

Immunogen:
Synthetic peptide corresponding to residues C(194) G K I E V E K P F A I A K E(208) of human CyPB

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA1031

--


Antigen:
ALG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
alg-1

Gene Alias:
Alg1; alg-1; ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase; ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase; Argonaute; Argonaute-like; asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase); asparagine-linked glycosylation 1 homolog (S. cerevisiae, beta-1,4-mannosyltransferase); asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase); asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog; asparagine-linked glycosylation protein 1 homolog; beta-1,4 mannosyltransferase; beta-1,4-mannosyltransferase; CDG1K; CELE_F48F7.1; chitobiosyldiphosphodolichol beta-mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase; HMAT1; hMat-1; HMT1; HMT-1; Mannosyltransferase-1; Mat-1; MT-1; Protein argonaute; protein-coding; PSEC0061; UNQ861/PRO1870

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
181504

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
0

Gene Symbols:
alg-1

Immunogen:
Peptide sequence DLEEIPNSPPTQPQTFSDVPQR

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
C. elegans

Product Type:
Antibody

Isotype:
IgG