PIPA121354
IL-21 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA121354-Each-of-1 | In Stock | ₹ 50,737.08 |
PIPA121354 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,737.08
GST (18%): ₹ 9,132.674
Total Price: ₹ 59,869.754
Antigen
IL-21
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IL21
Gene Alias
CVID11; CX2; il 21; IL21; IL-21; ILN; Interleukin; interleukin 21; Interleukin21; interleukin-21; interleukin-21 isoform; porcine interleukin-21; Za11
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
59067
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA
Concentration
1 mg/mL
Formulation
0.01M potassium phosphate with 0.14M NaCl, 1mg/mL BSA and 0.1% sodium azide
Gene Accession No.
Q9HBE4
Gene Symbols
IL21
Immunogen
Synthetic peptide of Human IL21 C terminal amino acids 118-146 [CDSYEKKPPKEFLERFKSLLQKMIHQHLS]
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: Human spleen cells
- IL-21 is a 17 kDa immunomodulatory cytokine produced mainly by Natural Killer Cells (NKT), T helper (Th) 17 and T follicular helper (TFH) cells
- In TFH cells, IL-21 expression leads to autocrine signaling through the IL-21 receptor (IL-21R) and STAT3, which leads to additional transcriptional activation by Bcl6
- As with IFN gamma for Th1 and IL-4 for Th2 cells, IL-21 is critical for TFH cell development and effector function
- IL-21 plays a role in T cell-dependent B cell differentiation into plasma cells and memory cells, stimulation of IgG production and induction of apoptotic signaling in naive B cells
- In Th17 cells, IL-21 expression and autocrine feedback through STAT3, IRF4 and ROR gamma t lead to upregulation of the IL-23R, thereby preparing Th17 cells for maturation and maintenance by the inflammatory cytokine IL-23
- While upregulating IRF4 and ROR gamma t, IL-21 also mediates the downregulation of Foxp3
- IL-21 deficient mice are protected from developing colitis upon chemical treatment by their inability to upregulate Th17-associated molecules
- In comparison, elevated levels of IL-21 are present in chemically-induced colitis mouse models.
Compare Similar Items
Show Difference
Antigen: IL-21
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL21
Gene Alias: CVID11; CX2; il 21; IL21; IL-21; ILN; Interleukin; interleukin 21; Interleukin21; interleukin-21; interleukin-21 isoform; porcine interleukin-21; Za11
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 59067
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA
Concentration: 1 mg/mL
Formulation: 0.01M potassium phosphate with 0.14M NaCl, 1mg/mL BSA and 0.1% sodium azide
Gene Accession No.: Q9HBE4
Gene Symbols: IL21
Immunogen: Synthetic peptide of Human IL21 C terminal amino acids 118-146 [CDSYEKKPPKEFLERFKSLLQKMIHQHLS]
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
IL-21
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL21
Gene Alias:
CVID11; CX2; il 21; IL21; IL-21; ILN; Interleukin; interleukin 21; Interleukin21; interleukin-21; interleukin-21 isoform; porcine interleukin-21; Za11
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
59067
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA
Concentration:
1 mg/mL
Formulation:
0.01M potassium phosphate with 0.14M NaCl, 1mg/mL BSA and 0.1% sodium azide
Gene Accession No.:
Q9HBE4
Gene Symbols:
IL21
Immunogen:
Synthetic peptide of Human IL21 C terminal amino acids 118-146 [CDSYEKKPPKEFLERFKSLLQKMIHQHLS]
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: IL22RA2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL22RA2
Gene Alias: CRF2-10; CRF2-S1; CRF2X; Cytokine receptor class-II member 10; Cytokine receptor family 2 member 10; cytokine receptor family II soluble 1; cytokine receptor family type 2, soluble 1; IL-22 receptor subunit alpha-2; IL22BP; IL-22BP; Il22ra2; IL-22RA2; IL-22R-alpha-2; interleukin 22 receptor subunit alpha 2; interleukin 22 receptor, alpha 2; interleukin 22-binding protein; interleukin-22 receptor subunit alpha-2; Interleukin-22-binding protein; UNQ5793/PRO19598/PRO19822; ZcytoR16
Host Species: Goat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 116379, 237310, 444986
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: 0.01M potassium phosphate with 0.14M NaCl, 1mg/mL BSA and 0.1% sodium azide
Gene Accession No.: Q7TNI4, Q80XF5, Q969J5
Gene Symbols: IL22RA2
Immunogen: Synthetic peptide of Human IL22 RA2 N terminal amino acids 33-60 [RVQFQSRNFHNILQWQPGRALTGNSSVYC]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IL22RA2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL22RA2
Gene Alias:
CRF2-10; CRF2-S1; CRF2X; Cytokine receptor class-II member 10; Cytokine receptor family 2 member 10; cytokine receptor family II soluble 1; cytokine receptor family type 2, soluble 1; IL-22 receptor subunit alpha-2; IL22BP; IL-22BP; Il22ra2; IL-22RA2; IL-22R-alpha-2; interleukin 22 receptor subunit alpha 2; interleukin 22 receptor, alpha 2; interleukin 22-binding protein; interleukin-22 receptor subunit alpha-2; Interleukin-22-binding protein; UNQ5793/PRO19598/PRO19822; ZcytoR16
Host Species:
Goat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
116379, 237310, 444986
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
0.01M potassium phosphate with 0.14M NaCl, 1mg/mL BSA and 0.1% sodium azide
Gene Accession No.:
Q7TNI4, Q80XF5, Q969J5
Gene Symbols:
IL22RA2
Immunogen:
Synthetic peptide of Human IL22 RA2 N terminal amino acids 33-60 [RVQFQSRNFHNILQWQPGRALTGNSSVYC]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: IL-22 Receptor alpha
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Il22ra1
Gene Alias: 9130219A07Rik; CRF2-9; Cytokine receptor class-II member 9; cytokine receptor family 2 member 9; ENSMUSG00000073746; il-22 receptor; IL-22 receptor subunit alpha-1; IL22R; IL-22R; IL22R1; IL22RA1; IL-22RA1; IL-22R-alpha-1; ILN; Interleukin; interleukin 22 receptor subunit alpha 1; interleukin 22 receptor, alpha 1; interleukin-22 receptor alpha chain; interleukin-22 receptor subunit alpha-1; RGD1559655; zcytoR11
Host Species: Goat
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 58985
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: 10mM potassium phosphate with 140mM NaCl, 1mg/mL BSA and 0.1% sodium azide
Gene Accession No.: Q8N6P7
Gene Symbols: Il22ra1
Immunogen: Synthetic peptide of Human IL22 Receptor N terminal amino acids 42-70 [DSGPEGTPDTVYSIEYKTYGERDWVAKK]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
IL-22 Receptor alpha
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Il22ra1
Gene Alias:
9130219A07Rik; CRF2-9; Cytokine receptor class-II member 9; cytokine receptor family 2 member 9; ENSMUSG00000073746; il-22 receptor; IL-22 receptor subunit alpha-1; IL22R; IL-22R; IL22R1; IL22RA1; IL-22RA1; IL-22R-alpha-1; ILN; Interleukin; interleukin 22 receptor subunit alpha 1; interleukin 22 receptor, alpha 1; interleukin-22 receptor alpha chain; interleukin-22 receptor subunit alpha-1; RGD1559655; zcytoR11
Host Species:
Goat
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
58985
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
10mM potassium phosphate with 140mM NaCl, 1mg/mL BSA and 0.1% sodium azide
Gene Accession No.:
Q8N6P7
Gene Symbols:
Il22ra1
Immunogen:
Synthetic peptide of Human IL22 Receptor N terminal amino acids 42-70 [DSGPEGTPDTVYSIEYKTYGERDWVAKK]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CCRD6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ACKR2
Gene Alias: Ackr2; AI464239; Atypical chemokine receptor 2; C-C chemokine receptor D6; Ccbp2; CC-chemokine-binding receptor JAB61; CCR10; CCR10-related receptor; CCR9; chemokine (C-C motif) receptor 9; chemokine (C-C) receptor 9; chemokine binding protein 2; chemokine decoy receptor D6; chemokine receptor CCR-10; Chemokine receptor CCR-9; chemokine receptor D6; chemokine-binding protein 2; Chemokine-binding protein D6; CMKBR9; D6; D6 beta-chemokine receptor; hD6
Host Species: Goat
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1238
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: 0.01M potassium phosphate with 0.14M NaCl, 1mg/mL BSA and 0.1% sodium azide
Gene Accession No.: O00590
Gene Symbols: ACKR2
Immunogen: Synthetic peptide corresponding to residues CLATEDADSENSSFYYYDYLDEVAFML of human CCRD6.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CCRD6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ACKR2
Gene Alias:
Ackr2; AI464239; Atypical chemokine receptor 2; C-C chemokine receptor D6; Ccbp2; CC-chemokine-binding receptor JAB61; CCR10; CCR10-related receptor; CCR9; chemokine (C-C motif) receptor 9; chemokine (C-C) receptor 9; chemokine binding protein 2; chemokine decoy receptor D6; chemokine receptor CCR-10; Chemokine receptor CCR-9; chemokine receptor D6; chemokine-binding protein 2; Chemokine-binding protein D6; CMKBR9; D6; D6 beta-chemokine receptor; hD6
Host Species:
Goat
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1238
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
0.01M potassium phosphate with 0.14M NaCl, 1mg/mL BSA and 0.1% sodium azide
Gene Accession No.:
O00590
Gene Symbols:
ACKR2
Immunogen:
Synthetic peptide corresponding to residues CLATEDADSENSSFYYYDYLDEVAFML of human CCRD6.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG