PIPA124792

IL5RA (soluble) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA124792-Each-of-1 In Stock ₹ 44,790.66

PIPA124792 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

IL5RA (soluble)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL5RA

Gene Alias

CD125; CD125 antigen; CDw125; HSIL5R3; IL-5 receptor alpha chain; IL-5 receptor subunit alpha; Il5r; IL-5R subunit alpha; Il5ra; IL-5RA; IL-5R-alpha; interleukin 5 receptor subunit alpha; interleukin 5 receptor type 3; interleukin 5 receptor, alpha; interleukin-5 receptor alpha chain; interleukin-5 receptor subunit alpha

Host Species

Goat

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3568

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Inhibition Assays, Neutralization, Western Blot

Concentration

0.1 mg/mL

Formulation

PBS with 5% trehelose and no preservative; pH 7.4

Gene Accession No.

Q01344

Gene Symbols

IL5RA

Immunogen

Purified, recombinant human interleukin 5 soluble receptor alpha (IL5RA) expressed in insect Sf 21 cells.

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: human blood-derived granulocytes
  • The Neutralization Dose50 (ND50) for anti-human IL5RA is approximately 1-3 μg/mL in the presence of 0.5 ng/mL of recombinant human IL-5 using the human TF-1 cell line
  • The ND50 is the concentration of antibody required to yield one-half maximal inhibition of the cell surface IL5RA mediated IL5 response on a responsive cell line, at a specific IL5 concentration
  • The exact concentration of antibody required to neutralize the human cell surface IL5RA mediated bioactivity is dependent on the IL5 concentration as well as on the number of IL5RA present on the cell surface (a function of the cell type and culture conditions)
  • Interleukin 5 (IL-5) is a soluble T cell-derived factor, also known as T cell replacing factor (TRF), that induces B cell and eosinophil growth and differentiation
  • IL-5 exerts its biological activity through the IL-5 receptor (IL-5R), which is composed of two chains: an alpha chain that binds IL-5 with low affinity and a beta chain that does not bind IL-5, but together with the IL-5 alpha chain, constitutes the high affinity IL-5 receptor
  • The cytoplasmic domain of both the alpha and beta chains is essential for signal transduction
  • Specifically, the membrane-proximal proline-rich sequence of the cytoplasmic domain of the IL-5R receptor alpha subunit, IL-5Ralpha, is critical for the IL-5 induced proliferative response, expression of nuclear proto-oncogenes and tyrosine phosphorylation of cellular proteins, such as JAK1 and JAK2.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA124792

--


Antigen:
IL5RA (soluble)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL5RA

Gene Alias:
CD125; CD125 antigen; CDw125; HSIL5R3; IL-5 receptor alpha chain; IL-5 receptor subunit alpha; Il5r; IL-5R subunit alpha; Il5ra; IL-5RA; IL-5R-alpha; interleukin 5 receptor subunit alpha; interleukin 5 receptor type 3; interleukin 5 receptor, alpha; interleukin-5 receptor alpha chain; interleukin-5 receptor subunit alpha

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3568

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Inhibition Assays, Neutralization, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 5% trehelose and no preservative; pH 7.4

Gene Accession No.:
Q01344

Gene Symbols:
IL5RA

Immunogen:
Purified, recombinant human interleukin 5 soluble receptor alpha (IL5RA) expressed in insect Sf 21 cells.

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA124798

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Antigen:
IL-9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il9

Gene Alias:
cytokine P40; homolog of mouse T cell and mast cell growth factor 40; HP40; IL9; IL-9; ILN; Interleukin; interleukin 9; Interleukin9; interleukin-9; P40; p40 cytokine; p40 T-cell and mast cell growth factor; T-cell growth factor P40

Host Species:
Goat

Purification Method:
Ig fraction

Regulatory Status:
RUO

Gene ID (Entrez):
3578

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Inhibition Assays, Neutralization, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P15248

Gene Symbols:
Il9

Immunogen:
recombinant human IL-9 expressed in Sf 21 insect cells

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA124799

--


Antigen:
IL-9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il9

Gene Alias:
cytokine P40; homolog of mouse T cell and mast cell growth factor 40; HP40; IL9; IL-9; ILN; Interleukin; interleukin 9; Interleukin9; interleukin-9; P40; p40 cytokine; p40 T-cell and mast cell growth factor; T-cell growth factor P40

Host Species:
Goat

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
16198

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Neutralization, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P15247

Gene Symbols:
Il9

Immunogen:
recombinant mouse IL-9 expressed in Sf 21 insect cells

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA124827

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Antigen:
GDNF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GDNF

Gene Alias:
AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor

Host Species:
Goat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2668

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Inhibition Assays, Neutralization

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P39905

Gene Symbols:
GDNF

Immunogen:
Recombinant, full length human GDNF protein expressed in E. coli.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG