PIPA125150

NPHP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA125150-Each-of-1 In Stock ₹ 44,705.10

PIPA125150 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

NPHP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NPHP1

Gene Alias

JBTS4; juvenile nephronophthisis 1 protein; nephrocystin 1; Nephrocystin1; nephrocystin-1; nephronophthisis 1 (juvenile); nephronophthisis 1 (juvenile) homolog; nephronophthisis 1 (juvenile) homolog (human); NPH1; NPHP1; SLSN1

Host Species

Rabbit

Purification Method

IgG fraction

Regulatory Status

RUO

Gene ID (Entrez)

53885

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q9QY53

Gene Symbols

NPHP1

Immunogen

Fusion protein corresponding to the pic region (residues 612-691) of mouse NPH.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5110709

--

Img

Thermo Scientific

PIPA595474

--

Img

Thermo Scientific

PIPA534942

--

Img

Thermo Scientific

PIPA595503

--

Img

Thermo Scientific

PIPA5106847

--

Img

Thermo Scientific

PIPA5101707

--

Img

Thermo Scientific

PIPA536361

--

Img

Thermo Scientific

PIPA5116357

--

Description

  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Juvenile nephronophthisis type 1 is caused by mutations of NPHP1, the gene encoding for nephrocystin
  • Nephrocystin interacts with p130Cas (BCAR1), proline-rich tyrosine kinase-2 (PTK2B or Pyk2), and tensin in embryonic kidney and testis, indicating that these proteins participate in a common signaling pathway
  • Nephrocystin and p130Cas interact in mammalian cells and both proteins prominently localize at or near sites of cell-cell contact in polarized Madin-Darby canine kidney epithelial cells
  • Expression of nephrocystin results in phosphorylation of Pyk2 on Tyrosine 402 as well as activation of downstream mitogen-activated protein kinases, such as ERK1 and ERK2
  • Nephrocystin contains a src-homology 3 (SH3) domain, which is highly conserved throughout evolution.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA125150

--


Antigen:
NPHP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPHP1

Gene Alias:
JBTS4; juvenile nephronophthisis 1 protein; nephrocystin 1; Nephrocystin1; nephrocystin-1; nephronophthisis 1 (juvenile); nephronophthisis 1 (juvenile) homolog; nephronophthisis 1 (juvenile) homolog (human); NPH1; NPHP1; SLSN1

Host Species:
Rabbit

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
53885

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9QY53

Gene Symbols:
NPHP1

Immunogen:
Fusion protein corresponding to the pic region (residues 612-691) of mouse NPH.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA125152

--


Antigen:
Osteopontin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPP1

Gene Alias:
2AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bone sialoprotein 1 (BSPI/BSP1); Bsp; BSPI; Calcium oxalate crystal growth inhibitor protein; CALPHA1 fusion; Early T lymphocyte activation 1 (ETA1); early T-lymphocyte activation 1; early T-lymphocyte activation 1 protein; Eta; ETA-1; HGNC:11255; immunoglobulin alpha 1 heavy chain constant region fusion protein; MGC110940; Minopontin; nephropontin; Op; Opn; Opnl; OSP; osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1); secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); Secreted phosphoprotein 1 (SPP1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); SPP1; SPP-1; SPP1/CALPHA1 fusion; unnamed protein product; urinar; urinary stone protein; Uropontin

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20750

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Inhibition Assays, Neutralization, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 5% trehalose and no preservative

Gene Accession No.:
P10923

Gene Symbols:
SPP1

Immunogen:
Recombinant, full length mouse protein, expressed in NSO cells.

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA125162

--


Antigen:
Zyxin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZYX

Gene Alias:
9530098H06Rik; ESP-2; HED-2; LOW QUALITY PROTEIN: zyxin; R75157; ZYX; Zyxin; zyxin-2

Host Species:
Rabbit

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
114636, 22793, 7791

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
12.7 mg/mL

Formulation:
0.01M PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
Q15942, Q62523

Gene Symbols:
ZYX

Immunogen:
Synthetic peptide, conjugated to KLH at an N-terminal added cysteine, corresponding to residues 134-150 of human Zyxin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA125241

--


Antigen:
MMP23

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MMP23B

Gene Alias:
Femalysin; matrix metallo protease; matrix metallopeptidase 23A (pseudogene); matrix metallopeptidase 23B; matrix metalloproteinase 22; matrix metalloproteinase 23B; matrix metalloproteinase in the female reproductive tract; matrix metalloproteinase-21; Matrix metalloproteinase-22; matrix metalloproteinase-23; Matrix metalloproteinase-23, soluble form; MIFR; MIFR-1; MMP; MMP 23; MMP21; MMP-21; MMP22; MMP-22; MMP23; MMP-23; MMP23A; MMP23B; MMPs; RP11-345P4.2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8510, 8511

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.01M PBS with 50% glycerol and 15mM sodium azide; pH 7.4

Gene Accession No.:
O75900

Gene Symbols:
MMP23B

Immunogen:
Synthetic peptide corresponding to the hinge domain of human MMP-23.

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG