PIPA125435

TLR2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA125435-Each-of-1 In Stock ₹ 47,015.22

PIPA125435 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

TLR2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Tlr2

Gene Alias

CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

24088, 7097

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O60603, Q9QUN7

Gene Symbols

Tlr2

Immunogen

Mixture of synthetic peptides corresponding to residues 180-196, 353-370, and 473-489 of human TLR2.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-25435 detects TLR2 from human samples
  • TLR2 is a member of the Toll-like receptor (TLR) family which play a fundamental role in pathogen recognition and activation of innate immunity
  • TLR proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kappa-B
  • TLR2 can form heterodimers with either TLR1 or TLR6, and as a heterodimer, can recognize a variety of bacterial and mycoplasma lipoproteins respectively
  • TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
  • The various TLRs exhibit different patterns of expression
  • TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB
  • TLR2 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • Ten human homologs of TLRs (TLR1-10) have been described
  • TLR2 is expressed in human cells such as tonsils, microglia, lymph nodes, and appendices, activated B-cells in germinal centers
  • CD14+ monocytes express the highest level of TLR2 followed by CD15+ granulocytes, CD19+ B-cells, and CD3+ T-cells
  • The expression of TLR2 on different cell types are regulated by different immune response modifiers
  • For example, LPS, GM-CSF, IL-1, and IL-10 up regulates TLR2 whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.

Compare Similar Items

Show Difference

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PIPA125435

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Antigen:
TLR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tlr2

Gene Alias:
CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
24088, 7097

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O60603, Q9QUN7

Gene Symbols:
Tlr2

Immunogen:
Mixture of synthetic peptides corresponding to residues 180-196, 353-370, and 473-489 of human TLR2.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA125462

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Antigen:
H3K9acS10ph

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H3C1

Gene Alias:
Acetyl H3; Acetyl Histone H3; B0035.7; CELE_T10C6.12; CG31613; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; Dmel\CG31613; Dmel_CG31613; F07B7.10; F07B7.3; F08G2.2; F17E9.13; F35H10.1; F45F2.4; F54E12.5; F55G1.10; H02I12.7; h3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K9; H3 K9ac; H3 S10; H3 S10ph; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3 histone A; H3.3 histone B; H3.3A; H3.3b; H3.5; H3.5 histone; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-5; H3-53; H3-614; H3a; H3b; H3-B; H3C1; H3c10; H3

Host Species:
Rabbit

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
107131750, 126961, 180073, 260423, 318847, 319150, 319152, 333932, 360198, 399088, 616800, 788250, 8350, 8356, 8357, 8358, 8968, 97114

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3.7 mg/mL

Formulation:
0.01M PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P09588, P68431, P68433, P84228, Q71DI3

Gene Symbols:
H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7, h3c8.S, his-3, His3:CG31613, LOC107131750

Immunogen:
Synthetic, acetylated and phosphorylated (acetyl K9 & phospho S10) peptide, conjugated to KLH, corresponding to the N-terminal residues 7-20 of human Histone H3.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Amphibian, Bovine, C. elegans, Chicken, Drosophila, Human, Mouse, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG

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PIPA125472

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Antigen:
SIRT2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIRT2

Gene Alias:
5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; Sirt2; sirtuin 2; sirtuin type 2; sirtuin-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22933, 64383

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.33 mg/mL

Formulation:
0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
Q8IXJ6, Q8VDQ8

Gene Symbols:
SIRT2

Immunogen:
Synthetic peptide corresponding to the C-terminal residues 722-737 of mouse SIR2/SIRT2, with a C-terminal added lysine.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA125512

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Antigen:
ASAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ASAP1

Gene Alias:
130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein; 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein; ADP-ribosylation factor-directed GTPase-activating protein 1; AMAP1; ARF GTPase-activating protein 1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1; ArfGAP with SH3 domain, ankyrin repeat and PH domain 1; ArfGAP with SH3 domain, ankyrin repeat and PH domain1; Asap1; AV239055; centaurin, beta 4; CENTB4; Ddef1; DEF-1; development and differentiation enhancing factor 1; development and differentiation-enhancing factor 1; differentiation enhancing factor 1; differentiation-enhancing factor 1; Kiaa1249; mKIAA1249; PAG2; PAP; PIP2-dependent ARF1 GAP; s19; Shag1; src SH3 binding protein; ZG14P

Host Species:
Rabbit

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
13196, 314961, 327705, 50807

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
11.6 mg/mL

Formulation:
0.01M PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
O97902, Q9ULH1, Q9QWY8, Q1AAU6

Gene Symbols:
ASAP1

Immunogen:
Synthetic peptide, conjugated to KLH, corresponding to residues 1128-1147 of mouse Centaurin beta 4. The peptide sequence is identical in bovine ASAP1

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG