PIPA129797

MBD1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA129797-Each-of-1 In Stock ₹ 47,015.22

PIPA129797 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

MBD1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MBD1

Gene Alias

CXXC3; CXXC-type zinc finger protein 3; Mbd1; methyl-CpG binding domain protein 1; methyl-CpG binding domain protein 1 isoform PCM1; methyl-CpG-binding domain protein 1; Methyl-CpG-binding protein MBD1; PCM1; Protein containing methyl-CpG-binding domain 1; RFT; the regulator of fibroblast growth factor 2 (FGF-2) transcription

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

4152

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q9UIS9

Gene Symbols

MBD1

Immunogen

Synthetic peptides RQVGPQSGEVKEAPR and PEEDKEENKDDSASK, corresponding to amino acids 98-113 and 342-356 of Human MBD1, respectively.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA124843

--

Img

Thermo Scientific

PIPA132488

--

Img

Thermo Scientific

PIPA146133

--

Img

Thermo Scientific

PIPA130046

--

Img

Thermo Scientific

PIPA131506

--

Img

Thermo Scientific

PIPA120698

--

Img

Thermo Scientific

PIPA129811

--

Img

Thermo Scientific

PIPA131317

--

Description

  • PA1-29797 detects MBD1 from human samples
  • Methyl-CpG-binding domain protein 1 (MBD1) is a member of a family of mammalian proteins that specifically bind methylated regions of DNA
  • It is a transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides
  • Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS)
  • MBD1 acts as a transcriptional repressor and plays a role in gene silencing by recruiting AFT7IP, which in turn recruits factors such as the histone methyltransferase SETDB1
  • Isoform 1 and isoform 2 can also repress transcription from unmethylated promoters.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA129797

--


Antigen:
MBD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MBD1

Gene Alias:
CXXC3; CXXC-type zinc finger protein 3; Mbd1; methyl-CpG binding domain protein 1; methyl-CpG binding domain protein 1 isoform PCM1; methyl-CpG-binding domain protein 1; Methyl-CpG-binding protein MBD1; PCM1; Protein containing methyl-CpG-binding domain 1; RFT; the regulator of fibroblast growth factor 2 (FGF-2) transcription

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4152

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9UIS9

Gene Symbols:
MBD1

Immunogen:
Synthetic peptides RQVGPQSGEVKEAPR and PEEDKEENKDDSASK, corresponding to amino acids 98-113 and 342-356 of Human MBD1, respectively.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA129799

--


Antigen:
SET

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SET

Gene Alias:
2610030F17Rik; 2PP2A; 5730420M11Rik; AA407739; Ab1-115; HLA-DR-associated protein II; hypothetical protein LOC538444; I IGAAD; I2PP2A; I-2PP2A; IGAAD; inhibitor of granzyme A-activated DNase; inhibitor-2 of protein phosphatase-2A; IPP2A2; Liver regeneration-related protein LRRGR00002; OTTHUMP00000022286; PHAPII; Phosphatase 2A inhibitor I2PP2A; protein phosphatase 2A inhibitor 2; protein phosphatase type 2A inhibitor; protein SET; RP11-216B9.3; Set; SET nuclear oncogene; SET nuclear proto-oncogene; SET translocation; SET translocation (myeloid leukemia-associated); SET-like protein; StF-IT-1; TAF-1a; TAF-1b; TAF-I; TAF-IBETA; Template-activating factor I; Template-Activating Factor-I, chromatin remodelling factor

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
307947, 56086, 6418

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
Q01105, Q63945, Q9EQU5

Gene Symbols:
SET

Immunogen:
Synthetic peptides, corresponding to amino acids 66-81 and 135-151 of Human INHAT1.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA129801

--


Antigen:
TRF4-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TENT4A

Gene Alias:
DNA polymerase kappa; DNA polymerase sigma; LAK1; LAK-1; non-canonical poly(A) RNA polymerase PAPD7; PAP associated domain containing 7; PAP-associated domain-containing protein 7; Papd7; POLK; POLS; polymerase (DNA directed) sigma; polymerase (DNA-directed) sigma; Tent4a; Terminal guanylyltransferase; Terminal nucleotidyltransferase 4A; Terminal uridylyltransferase 5; topoisomerase-related function protein 4-1; TRAMP-like complex polyadenylate polymerase; TRF4; TRF41; TRF4-1; TUTase 5; TUTASE5

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11044

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q5XG87

Gene Symbols:
TENT4A

Immunogen:
Synthetic peptide, corresponding to amino acids 447-462 of Human TRF41.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA129811

--


Antigen:
TMEM123

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMEM123

Gene Alias:
2310075C12Rik; KCT3; KCT-3; keratinocytes associated transmembrane protein 3; keratinocytes-associated transmembrane protein 3; Porimin; PORMIN; pro oncosis receptor inducing membrane injury; pro-oncosis receptor inducing membrane injury; PSEC0111; RGD1305625; serine/threonine-rich receptor; TMEM123; Transmembrane protein 123; UNQ641/PRO1271

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
114908, 71929

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q8N131, Q91Z22

Gene Symbols:
TMEM123

Immunogen:
synthetic peptide SRRGIRYRTIDEHDAI, corresponding to amino acids 173-188 of Human Porimin

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG