PIPA129825

SIGIRR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA129825-Each-of-1 In Stock ₹ 47,015.22

PIPA129825 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

SIGIRR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SIGIRR

Gene Alias

AI256711; IL-1R8; MGC110992; Sigirr; single Ig and TIR domain containing; single Ig IL-1 receptor related protein; single Ig IL-1-related receptor; Single Ig IL-1R-related molecule; single Ig IL-1R-related protein; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single immunoglobulin domain IL1R1 related; single immunoglobulin domain-containing IL1R-related protein; TIR8; Toll/interleukin-1 receptor 8; UNQ301/PRO342

Host Species

Rabbit

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum diluted in PBS with 0.1mg/mL BSA and 0.02% sodium azide

Gene Accession No.

Q6IA17

Gene Symbols

SIGIRR

Immunogen

Synthetic peptides corresponding to aa 309-323 and 380-393 of human SIGIRR.

Regulatory Status

RUO

Gene ID (Entrez)

59307

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • PA1-29825 detects SIGIRR from human samples
  • SIGIRR (single Ig IL-1R-related molecule) is a novel member of the interleukin 1 receptor (IL-1R) superfamily
  • Although it shows the typical conserved motifs that characterize the IL-1R and Toll superfamily, it is structurally and functionally distinct from both
  • SIGIRR has only one Ig domain in its extracellular portion whereas the IL-1R family contains three Ig folds
  • An unusually long cytoplasmic domain is reminiscent of the structure of drosophila Toll, yet the SIGIRR peptide sequence is more closely related to IL-1RI
  • A chimera, in which the SIGIRR intracellular domain was fused to the IL-1R extracellular domain, did not activate NFkappaB unlike similar fusion proteins of other IL-1R related molecules
  • Phylogenetic data that suggest that the plasma membrane protein SIGIRR is a close functional relative of MyD88 in mammals.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA129825

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Antigen:
SIGIRR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIGIRR

Gene Alias:
AI256711; IL-1R8; MGC110992; Sigirr; single Ig and TIR domain containing; single Ig IL-1 receptor related protein; single Ig IL-1-related receptor; Single Ig IL-1R-related molecule; single Ig IL-1R-related protein; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single immunoglobulin domain IL1R1 related; single immunoglobulin domain-containing IL1R-related protein; TIR8; Toll/interleukin-1 receptor 8; UNQ301/PRO342

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum diluted in PBS with 0.1mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
Q6IA17

Gene Symbols:
SIGIRR

Immunogen:
Synthetic peptides corresponding to aa 309-323 and 380-393 of human SIGIRR.

Regulatory Status:
RUO

Gene ID (Entrez):
59307

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

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PIPA129834

--


Antigen:
TBLR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TBL1XR1

Gene Alias:
8030499H02Rik; A630076E03Rik; AW539987; C21; C230089I12Rik; DC42; F-box-like/WD repeat protein TBL1XR1; F-box-like/WD repeat-containing protein TBL1XR1; FLJ12894; Ira1; MRD41; nuclear receptor co-repressor/HDAC3 complex subunit; nuclear receptor corepressor/HDAC3 complex subunit TBLR1; RGD1560053; TBL1-related protein 1; TBL1XR1; TBLR1; transducin (beta)-like 1 X-linked receptor 1; transducin (beta)-like 1X-linked receptor 1; transducin beta-like 1X-related protein 1

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.2% gelatin and 0.05% sodium azide

Gene Accession No.:
Q9BZK7

Gene Symbols:
TBL1XR1

Immunogen:
synthetic peptide WPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWT, corresponding to amino acids 200-250 of Human TBLR1.

Regulatory Status:
RUO

Gene ID (Entrez):
79718

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

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PIPA129840

--


Antigen:
TXNDC5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Txndc5

Gene Alias:
AL022641; ENDOPDI; endoplasmic reticulum protein ERp46; endoplasmic reticulum resident protein 46; endothelial protein disulphide isomerase; ER protein 46; ERp46; FLJ21353; FLJ90810; HCC2; HCC-2; MGC3178; PC-TRP; PDIA15; Plasma cell-specific thioredoxin-related protein; protein disulfide isomerase family A, member 15; STRF8; thiore; thioredoxin domain containing 5; thioredoxin domain containing 5 (endoplasmic reticulum); thioredoxin domain-containing protein 5; thioredoxin related protein; thioredoxin-like protein p46; Tlp46; TXNDC5; UNQ364; UNQ364/PRO700

Host Species:
Goat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8NBS9

Gene Symbols:
Txndc5

Immunogen:
synthetic peptide SLHRFVLSQAKDEL (Human) (C terminal).

Regulatory Status:
RUO

Gene ID (Entrez):
81567

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA129843

--


Antigen:
IL21R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il21r

Gene Alias:
CD360; IL-21 receptor; Il21r; IL-21R; interleukin 21 receptor; interleukin-21 receptor; LR-beta; lymphocyte receptor beta; MGC10967; NILR; novel cytokine receptor 8; Novel interleukin receptor; NR8; UNQ3121/PRO10273

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.2% gelatin and 0.05% sodium azide

Gene Accession No.:
Q9HBE5

Gene Symbols:
Il21r

Immunogen:
Synthetic peptides (CSLHRSAHNATHATYT & CDFTSPGDEGPPRSYLR) corresponding to amino acids 65-80 and 505-521 of Human IL21R respectively.

Regulatory Status:
RUO

Gene ID (Entrez):
50615

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid