PIPA131714

DNMT3L Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA131714-Each-of-1 In Stock ₹ 47,186.34

PIPA131714 - Each of 1

₹ 47,186.34

In Stock

Quantity

1

Base Price: ₹ 47,186.34

GST (18%): ₹ 8,493.541

Total Price: ₹ 55,679.881

Antigen

DNMT3L

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DNMT3L

Gene Alias

cytosine-5-methyltransferase 3-like protein; D6Ertd14e; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; DNA methyltransferase 3 like; Dnmt 3L; DNMT3L; ecat7; human cytosine-5-methyltransferase 3-like protein; MGC1090

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29947

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

1.11 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

Q9UJW3

Gene Symbols

DNMT3L

Immunogen

synthetic peptide C-GLLQRRRKWRSQL conjugated to KLH, corresponding to amino acids 152-164 of Human DNMT 3L.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-31714 detects Dnmt3L from human samples
  • Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting, and development
  • Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2, and DNMT3
  • DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication
  • DNMT3A and DNMT3B are strongly expressed in embryonic stem cells with reduced expression in adult somatic tissues
  • DNMT3A and DNMT3B function as de novo methyltransferases that methylate previously unmethylated regions of DNA
  • DNMT2 is expressed at low levels in adult somatic tissues and its inactivation affects neither de novo nor maintenance DNA methylation
  • DNMT3L is a catalytically inactive regulatory factor for the DNMT3A and DNMT3B de novo methyltransferases that is expressed at low levels in embryonic stem cells, testis, ovaries, and thymus
  • These de novo methyltransferases consist of a heterotetrameric complex containing two molecules of DNMT3L, and either two molecules of DNMT3A or DNMT3B
  • DNMT3L contains an amino-terminal ATRX-DNMT3-DNMT3L (ADD) domain and a carboxy-terminal methyltransferase-like domain.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA131714

--


Antigen:
DNMT3L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNMT3L

Gene Alias:
cytosine-5-methyltransferase 3-like protein; D6Ertd14e; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; DNA methyltransferase 3 like; Dnmt 3L; DNMT3L; ecat7; human cytosine-5-methyltransferase 3-like protein; MGC1090

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29947

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1.11 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q9UJW3

Gene Symbols:
DNMT3L

Immunogen:
synthetic peptide C-GLLQRRRKWRSQL conjugated to KLH, corresponding to amino acids 152-164 of Human DNMT 3L.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA131798

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Antigen:
RAD23A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD23A

Gene Alias:
2310040P19Rik; AL024030; HHR23A; HR23A; MGC111083; Mhr23a; rad23; RAD23 homolog A (S. cerevisiae); RAD23 homolog A, nucleotide excision repair protein; RAD23, yeast homolog, A; RAD23A; RAD23a homolog (S. cerevisiae); UV excision repair protein RAD23 homolog A

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5886

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1.2 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P54725

Gene Symbols:
RAD23A

Immunogen:
synthetic peptide KSPSEESAPTTSPEC, corresponding to amino acids 122-135 of Human hHR23A.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA131805

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Antigen:
RNF3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PCGF3

Gene Alias:
2310035N15Rik; AI662857; D630042K08Rik; D6S113E; DADB-17J1.3; DKFZp686D20235; DKFZp686N0336; DONG1; E430039C14; FLJ31942; FLJ36550; FLJ43813; FSH; FSRG1; KIAA9001; MGC129075 protein; MGC129615; MGC40413; NAT; PCGF3; polycomb group ring finger 3; polycomb group RING finger protein 3; ring finger protein 3; RING finger protein 3A; RING3; RNF3; RNF3A

Host Species:
Goat

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
10336

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q3KNV8

Gene Symbols:
PCGF3

Immunogen:
Peptide with sequence PLLLHYRPKMDLL, from C Terminus of the protein sequence according to NP_006306.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA131895

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Antigen:
TRIM4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIM4

Gene Alias:
E3 ubiquitin-protein ligase TRIM4; RING finger protein 87; RING-type E3 ubiquitin transferase TRIM4; RNF87; TRIM4; tripartite motif containing 4; tripartite motif protein 4; tripartite motif-containing 4; Tripartite motif-containing protein 4

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
89122

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9C037

Gene Symbols:
TRIM4

Immunogen:
synthetic peptide ASLVIPPVTDRK from C Terminus of the protein sequence according to NP_148977; NP_149082.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG