PIPA131989

ErbB3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA131989-Each-of-1 In Stock ₹ 58,779.72

PIPA131989 - Each of 1

₹ 58,779.72

In Stock

Quantity

1

Base Price: ₹ 58,779.72

GST (18%): ₹ 10,580.35

Total Price: ₹ 69,360.07

Antigen

ErbB3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ERBB3

Gene Alias

avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

13867, 2065

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1.3 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P21860, Q61526

Gene Symbols

ERBB3

Immunogen

KLH conjugated synthetic peptide between 24-55 amino acids from the N-terminal region of human ERBB3.

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Western blot detects a band of ∽148 kDa, and has a predicted molecular weight of 161 kDa
  • Mouse brain lysate can be used as a positive control
  • ErbB3 (c-erbB-3/HER-3) is a member of the type I family of growth factor receptors and binds to ligands in the heregulin family
  • ErbB3 is over-expressed in a variety of tumors in the prostate, bladder, breast, stomach, pancreas, and colon
  • Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents
  • The ErbB3 gene is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6
  • 2kb mRNA which is translated into a 160/180 kDa glycoprotein
  • The ErbB3 gene encodes a transmembrane receptor tyrosine kinase due to alternative splicing and forms heterodimers with other EGF receptor family members that have kinase activity
  • Heterodimerization leads to the activation of pathways that lead to cell proliferation or differentiation
  • Alternate transcriptional splice variants encoding different isoforms of ErbB3 have been characterized
  • One ErbB3 isoform lacks the intermembrane region, is secreted outside the cell, and acts to modulate the activity of the membrane-bound form
  • Additional splice variants have also been reported, but they have not been thoroughly characterized.

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Thermo Scientific

PIPA131989

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Antigen:
ErbB3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB3

Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
13867, 2065

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.3 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P21860, Q61526

Gene Symbols:
ERBB3

Immunogen:
KLH conjugated synthetic peptide between 24-55 amino acids from the N-terminal region of human ERBB3.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA131990

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Antigen:
FGFR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FGFR2

Gene Alias:
AU043015; AW556123; bacteria-expressed kinase; BBDS; BEK; BEK fibroblast growth factor receptor; BFR-1; CD332; CEK3; CFD1; ECT1; FGF Receptor 2; FGF-10; FGFR2; FGFR-2; Fgfr7; Fgfr-7; fibroblast growth factor receptor 2; JWS; Keratinocyte growth factor receptor; KGFR; KGFRTr; KSAM; K-SAM; protein tyrosine kinase, receptor like 14; Soluble KGFR; svs; TK14; TK25

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14183, 2263

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P21802, P21803

Gene Symbols:
FGFR2

Immunogen:
KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human FGFR2.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA132079

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Antigen:
ATP6IP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Atp6ap2

Gene Alias:
(P)RR; (pro)renin receptor; 5730403E06Rik; APT6M8-9; ATP6AP2; Atp6ip2; ATP6M8-9; ATPase H(+)-transporting lysosomal accessory protein 2; ATPase H(+)-transporting lysosomal-interacting protein 2; ATPase H+ transporting accessory protein 2; ATPase, H(+)-transporting, lysosomal-interacting protein 2; ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9; ATPase, H+ transporting, lysosomal accessory protein 2; ATPase, H+ transporting, lysosomal interacting protein 1; ATPase, H+ transporting, lysosomal interacting protein 2; CAPER; ELDF10; embryonic liver differentiation factor 10; ER-localized type I transmembrane adaptor; HT028; M8-9; MGC99577; MRXE; MRXSH; MSTP009; N14F; prorenin receptor; PRR; PSEC0072; Renin receptor; Renin receptor C-terminal fragment; Renin receptor cytoplasmic fragment; Renin receptor extracellular fragment; Renin receptor N-terminal fragment; Renin/prorenin receptor; RENR; vacuolar ATP synthase membrane sector-associated protein M8-9; vacuolar proton ATP synthase membrane sector associated protein M8-9; V-ATPase M8.9 subunit; XMRE; XPDS

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10159, 302526, 70495

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75787, Q6AXS4, Q9CYN9

Gene Symbols:
Atp6ap2

Immunogen:
Peptide with sequence SIIYRMTNQKIRMD, from C Terminus of the protein sequence according to NP_005756

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA132114

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Antigen:
p130

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RBL2

Gene Alias:
130 kDa retinoblastoma-associated protein; FLJ26459; p130; PPAR-alpha-interacting complex protein 128; PRB2; PRIC128; RB transcriptional corepressor like 2; Rb2; rb2 p130; Rbl2; RBR-2; retinoblastoma-like 2; retinoblastoma-like 2 (p130); retinoblastoma-like protein 2; Retinoblastoma-related protein 2

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
19651, 5934, 81758

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
85 mg/mL

Formulation:
whole serum diluted in 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
O55081, Q08999, Q64700

Gene Symbols:
RBL2

Immunogen:
Rb2 (p130) peptide corresponding to a region near the C-terminus of the human protein conjugated to KLH

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG