Spiramycin Polyclonal Antibody, Invitrogen™

Description

• PA1-75409 specifically detects Spiramycin
• PA1-75409 has been successfully used in ELISA applications
• The PA1-75409 immunogen is Spiramycin-BTG
• Aminoglycosides are a family of bacterial antibiotics that are used in the treatment of specific bacterial infections
• They display a concentration dependent killing action and are active against a wide range of aerobic Gram-negative bacilli
• Aminoglycosides are molecules that are comprised of an amino group and a sugar group
• They operate by inhibiting the bacteria from producing proteins vital to its growth
• More specifically, they bind to the bacterial 30S ribosomal subunit where they prevent the translocation of the peptidyl-tRNA from the A-site to the P-site, subsequently giving rise to a misreading of mRNA resulting in the inhibition of protein synthesis
• This consequently results in a disruption to the integrity of the bacterial cell membrane
• In addition to their use to prevent bacterial infection, aminoglycosides have been used as growth promoters in food producing animals.