PIPA5100079

SPTLC2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100079-Each-of-1 In Stock ₹ 45,646.26

PIPA5100079 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

SPTLC2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPTLC2

Gene Alias

AI173915; hLCB2a; HSN1C; KIAA0526; LCB 2; LCB2; LCB2a; long chain base biosynthesis protein 2; Long chain base biosynthesis protein 2a; mKIAA0526; NSAN1C; Pomt2; protein-O-mannosyltransferase 2; serine palmitoyltransferase 2; serine palmitoyltransferase long chain base subunit 2; serine palmitoyltransferase, long chain base subunit 2; serine palmitoyltransferase, subunit II; serine-palmitoyl-CoA transferase 2; SPT 2; SPT2; Sptlc2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20773, 9517

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O15270, P97363

Gene Symbols

SPTLC2

Immunogen

A synthesized peptide derived from human SPTLC2(Accession O15270), corresponding to amino acid residues P367-E417.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total SPTLC2
  • Serine palmitoyltransferase (SPT), which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis
  • It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor
  • SPT2 is the long chain base subunit 2 of mammalian serine palmitoyltransferase
  • SPT2 is catalytically active but needs its related protein SPT1 for its stabilization and anchoring the holoenzyme to the cytosolic face of the endoplasmic reticulum
  • As in the case with SPT1, mutations in the SPT2 gene can cause hereditary sensory and autonomic neuropathy type I (HSAN-I), resulting from a loss of SPT activity as well as the accumulation of the atypical and neurotoxic sphingoid metabolite 1-deoxy-sphinganine.

Compare Similar Items

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Thermo Scientific

PIPA5100079

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Antigen:
SPTLC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPTLC2

Gene Alias:
AI173915; hLCB2a; HSN1C; KIAA0526; LCB 2; LCB2; LCB2a; long chain base biosynthesis protein 2; Long chain base biosynthesis protein 2a; mKIAA0526; NSAN1C; Pomt2; protein-O-mannosyltransferase 2; serine palmitoyltransferase 2; serine palmitoyltransferase long chain base subunit 2; serine palmitoyltransferase, long chain base subunit 2; serine palmitoyltransferase, subunit II; serine-palmitoyl-CoA transferase 2; SPT 2; SPT2; Sptlc2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20773, 9517

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O15270, P97363

Gene Symbols:
SPTLC2

Immunogen:
A synthesized peptide derived from human SPTLC2(Accession O15270), corresponding to amino acid residues P367-E417.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5100083

--


Antigen:
TMOD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMOD4

Gene Alias:
actin-capping protein; MTMOD; skeletal muscle tropomodulin; skeletal tropomodulin; SK-TMOD; TMOD4; tropomodulin 4; tropomodulin 4 (muscle); tropomodulin-4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
295261, 29765, 50874

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9JLH8, Q9NZQ9

Gene Symbols:
TMOD4

Immunogen:
A synthesized peptide derived from human TMOD4(Accession Q9NZQ9), corresponding to amino acid residues A149-E199.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5100086

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Antigen:
VPS16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VPS16

Gene Alias:
1810074M16Rik; hVPS16; mVPS16; RP11-12M19.2; vacuolar protein sorting 16 (yeast); vacuolar protein sorting 16 homolog; vacuolar protein sorting 16 homolog (S. cerevisiae); vacuolar protein sorting protein 16; vacuolar protein sorting-associated protein 16 homolog; VPS16; VPS16 CORVET/HOPS core subunit; VPS16, CORVET/HOPS core subunit

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
296159, 64601, 80743

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q920Q4, Q9H269

Gene Symbols:
VPS16

Immunogen:
A synthesized peptide derived from human VPS16(Accession Q9H269), corresponding to amino acid residues V330-V380.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5100089

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Antigen:
ASAH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ASAH1

Gene Alias:
2310081N20Rik; AC; ACDase; acid CDase; acid ceramidase; Acid ceramidase subunit alpha; Acid ceramidase subunit beta; Acylsphingosine deacylase; ASAH; Asah1; HSD33; HSD-33; N-acylethanolamine hydrolase ASAH1; N-acylsphingosine amidohydrolase; N-acylsphingosine amidohydrolase (acid ceramidase) 1; N-acylsphingosine amidohydrolase 1; PHP; PHP32; putative 32 kDa heart protein; SMAPME

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11886, 427, 84431

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13510, Q6P7S1, Q9WV54

Gene Symbols:
ASAH1

Immunogen:
A synthesized peptide derived from human ASAH1(Accession Q13510), corresponding to amino acid residues L12-W62.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG