PIPA5100139

DIO1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100139-Each-of-1 In Stock ₹ 43,592.82

PIPA5100139 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

DIO1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Dio1

Gene Alias

5DI; D1; deiodinase, iodothyronine type I; deiodinase, iodothyronine, type I; Dio1; DIOI; hDido1; iodothyronine deiodinase type 1; ITDI1; thyroxine 5'-deiodinase; thyroxine deiodinase; thyroxine deiodinase type I (selenoprotein); thyroxine deiodinase, type I; TXDI1; Type 1 DI; type I iodothyronine deiodinase; Type-I 5'-deiodinase

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13370, 1733, 25430

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P24389, P49895, Q61153

Gene Symbols

Dio1

Immunogen

A synthesized peptide derived from human DIO1(Accession P49895), corresponding to amino acid residues Q220-S249.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total DIO1
  • The protein encoded by this gene is a thiol-requiring propylthiouracil-sensitive oxidoreductase
  • It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3)
  • It also degrades both hormones by inner ring deiodination (IRD)
  • Alternative splicing results in multiple transcript variants encoding different isoforms
  • Some, but not all, isoforms contain a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination
  • The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal
  • Additional transcript variants have been described but are not supported by experimental evidence.

Compare Similar Items

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Img

Thermo Scientific

PIPA5100139

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Antigen:
DIO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dio1

Gene Alias:
5DI; D1; deiodinase, iodothyronine type I; deiodinase, iodothyronine, type I; Dio1; DIOI; hDido1; iodothyronine deiodinase type 1; ITDI1; thyroxine 5'-deiodinase; thyroxine deiodinase; thyroxine deiodinase type I (selenoprotein); thyroxine deiodinase, type I; TXDI1; Type 1 DI; type I iodothyronine deiodinase; Type-I 5'-deiodinase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13370, 1733, 25430

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P24389, P49895, Q61153

Gene Symbols:
Dio1

Immunogen:
A synthesized peptide derived from human DIO1(Accession P49895), corresponding to amino acid residues Q220-S249.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100140

--


Antigen:
DIS3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DIS3

Gene Alias:
2810028N01Rik; bA555G22.1; DIS3; DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; DIS3 mitotic control homolog; DIS3 mitotic control homolog (S. cerevisiae); dis3p; EXOSC11; exosome complex exonuclease RRP44; exosome component 11; KIAA1008; mitotic control protein dis3 homolog; protein DIS3 homolog; RGD1304646; Ribosomal RNA-processing protein 44; RP11-342J4.3; RRP44

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22894, 306103, 72662

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9CSH3, Q9Y2L1

Gene Symbols:
DIS3

Immunogen:
A synthesized peptide derived from human DIS3(Accession Q9Y2L1), corresponding to amino acid residues L736-I786.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5100141

--


Antigen:
DOM3Z

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DXO

Gene Alias:
decapping and exoribonuclease protein; decapping exoribonuclease; dom-3 homolog Z; DOM3L; DOM3Z; Dxo; NG6; protein Dom3Z; RAI1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
112403, 1797, 361799

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O70348, O77932, Q6MG77

Gene Symbols:
DXO

Immunogen:
A synthesized peptide derived from human DXO(Accession O77932), corresponding to amino acid residues A66-R116.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5100143

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Antigen:
ETFDH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Etfdh

Gene Alias:
0610010I20Rik; AV001013; electron transfer flavoprotein dehydrogenase; electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; electron transferring flavoprotein dehydrogenase; electron transferring flavoprotein, dehydrogenase; electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase; Etfdh; ETFQO; ETF-QO; ETF-ubiquinone oxidoreductase; MADD

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2110, 295143, 66841

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q16134, Q6UPE1, Q921G7

Gene Symbols:
Etfdh

Immunogen:
A synthesized peptide derived from human ETFDH(Accession Q16134), corresponding to amino acid residues N528-R578.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG