PIPA5100189
UFD1L Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5100189-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5100189 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
UFD1L
Classification
Polyclonal
Conjugate
Unconjugated
Gene
UFD1
Gene Alias
RGD:619822}; UB fusion protein 1; UB fusion protein 1 {ECO:0000250; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation protein 1; Ubiquitin fusion degradation protein 1 homolog; ubiquitin fusion degradation protein 1 homolog {ECO:0000250; Ubiquitin recognition factor in ER-associated degradation protein 1; UFD1; UFD1L; ufd1l {ECO:0000312; UniProtKB:Q92890}
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22230, 7353, 84478
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P70362, Q92890, Q9ES53
Gene Symbols
UFD1
Immunogen
A synthesized peptide derived from human UFD1(Accession Q92890), corresponding to amino acid residues G218-I268.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total UFD1L
- Ubiquitin-mediated proteolysis requires the transfer of ubiquitin (Ub) to lysine groups on selected cellular proteins, which then potentiates the proteolytic degradation of these protein conjugates by the 26S proteasome
- Ub-fusions are cleaved by Ub-specific processing proteases (UBps) or alternatively by the Ub-fusion degradation (UFD) pathway
- The UBP pathway targets the C-terminal glycine residue on Ub that is involved in the formation of Ub-conjugates, while UFD proteins preferentially cleave Ub-conjugated proteins that contain an amino acid substitution at this glycine residue
- The UFD1 protein was originally characterized in the yeast S
- cerevisiae and subsequently, the human homolog UFD1 or UFD1L was identified
- In vitro, UFD1 attenuates the degradation of Ub-fusions, which have a proline or valine residue substituted at the Gly76 moiety, by the selective multiubiquitination of the Ub chain of the Ub-conjugate
- Mutations within the UFD1 gene are implicated in the development of CATCH22 syndrome, which is characterized by cardiac defects, cleft palate and hypocalcemia, suggesting that this proteolytic pathway may be involved in the progression of these developmental defects.
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Antigen: UFD1L
Classification: Polyclonal
Conjugate: Unconjugated
Gene: UFD1
Gene Alias: RGD:619822}; UB fusion protein 1; UB fusion protein 1 {ECO:0000250; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation protein 1; Ubiquitin fusion degradation protein 1 homolog; ubiquitin fusion degradation protein 1 homolog {ECO:0000250; Ubiquitin recognition factor in ER-associated degradation protein 1; UFD1; UFD1L; ufd1l {ECO:0000312; UniProtKB:Q92890}
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22230, 7353, 84478
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P70362, Q92890, Q9ES53
Gene Symbols: UFD1
Immunogen: A synthesized peptide derived from human UFD1(Accession Q92890), corresponding to amino acid residues G218-I268.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
UFD1L
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
UFD1
Gene Alias:
RGD:619822}; UB fusion protein 1; UB fusion protein 1 {ECO:0000250; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation protein 1; Ubiquitin fusion degradation protein 1 homolog; ubiquitin fusion degradation protein 1 homolog {ECO:0000250; Ubiquitin recognition factor in ER-associated degradation protein 1; UFD1; UFD1L; ufd1l {ECO:0000312; UniProtKB:Q92890}
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22230, 7353, 84478
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P70362, Q92890, Q9ES53
Gene Symbols:
UFD1
Immunogen:
A synthesized peptide derived from human UFD1(Accession Q92890), corresponding to amino acid residues G218-I268.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: VDAC3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: VDAC3
Gene Alias: channel protein VDAC3; HD-VDAC3; mitochondrial outer membrane protein; mitochondrial voltage dependent anion channel 3; mVDAC3; outer mitochondrial membrane protein porin 3; rVDAC3; Vdac3; VDAC-3; voltage dependent anion channel 3; voltage-dependent anion channel 3; voltage-dependent anion-selective channel protein 3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22335, 7419, 83532
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q60931, Q9R1Z0, Q9Y277
Gene Symbols: VDAC3
Immunogen: A synthesized peptide derived from human VDAC3(Accession Q9Y277), corresponding to amino acid residues D30-T80.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
VDAC3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VDAC3
Gene Alias:
channel protein VDAC3; HD-VDAC3; mitochondrial outer membrane protein; mitochondrial voltage dependent anion channel 3; mVDAC3; outer mitochondrial membrane protein porin 3; rVDAC3; Vdac3; VDAC-3; voltage dependent anion channel 3; voltage-dependent anion channel 3; voltage-dependent anion-selective channel protein 3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22335, 7419, 83532
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q60931, Q9R1Z0, Q9Y277
Gene Symbols:
VDAC3
Immunogen:
A synthesized peptide derived from human VDAC3(Accession Q9Y277), corresponding to amino acid residues D30-T80.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: WDR18
Classification: Polyclonal
Conjugate: Unconjugated
Gene: WDR18
Gene Alias: 2310012I10Rik; AU044733; AW122032; Involved in Processing ITS2 3 homolog; Ipi3; R32184_1; WD repeat domain 18; WD repeat-containing protein 18; WDR18
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 216156, 314617, 57418
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q499N3, Q4VBE8, Q9BV38
Gene Symbols: WDR18
Immunogen: A synthesized peptide derived from human WDR18(Accession Q9BV38), corresponding to amino acid residues A308-T358.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
WDR18
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
WDR18
Gene Alias:
2310012I10Rik; AU044733; AW122032; Involved in Processing ITS2 3 homolog; Ipi3; R32184_1; WD repeat domain 18; WD repeat-containing protein 18; WDR18
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
216156, 314617, 57418
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q499N3, Q4VBE8, Q9BV38
Gene Symbols:
WDR18
Immunogen:
A synthesized peptide derived from human WDR18(Accession Q9BV38), corresponding to amino acid residues A308-T358.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ORP6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: OSBPL6
Gene Alias: ORP6; ORP-6; OSBPL6; OSBP-related protein 6; oxysterol binding protein like 6; oxysterol binding protein-like 6; oxysterol-binding protein-related protein 6
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114880
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9BZF3
Gene Symbols: OSBPL6
Immunogen: A synthesized peptide derived from human OSBPL6(Accession Q9BZF3), corresponding to amino acid residues I526-R576.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ORP6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
OSBPL6
Gene Alias:
ORP6; ORP-6; OSBPL6; OSBP-related protein 6; oxysterol binding protein like 6; oxysterol binding protein-like 6; oxysterol-binding protein-related protein 6
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114880
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9BZF3
Gene Symbols:
OSBPL6
Immunogen:
A synthesized peptide derived from human OSBPL6(Accession Q9BZF3), corresponding to amino acid residues I526-R576.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG