PIPA5100577

INTS3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100577-Each-of-1 In Stock ₹ 43,592.82

PIPA5100577 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

INTS3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

INTS3

Gene Alias

C1orf193; C1orf60; C77668; INT3; integrator complex subunit 3; Ints3; RGD1304593; Sensor of single-strand DNA complex subunit A; sensor of ssDNA subunit A; SOSS complex subunit A; SOSSA; SOSS-A

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

229543, 361988, 65123

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q68E01, Q7TPD0

Gene Symbols

INTS3

Immunogen

A synthesized peptide derived from human INTS3(Accession Q68E01), corresponding to amino acid residues P503-R553.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5100578

--

Img

Thermo Scientific

PIPA5100589

--

Img

Thermo Scientific

PIPA5100840

--

Img

Thermo Scientific

PIPA5100429

--

Img

Thermo Scientific

PIPA5100842

--

Img

Thermo Scientific

PIPA5100724

--

Img

Thermo Scientific

PIPA5101214

--

Img

Thermo Scientific

PIPA5100739

--

Description

  • Antibody detects endogenous levels of total INTS3
  • Component of the Integrator complex
  • The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing
  • The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.; FUNCTION: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint
  • The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability
  • The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways
  • In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5100577

--


Antigen:
INTS3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
INTS3

Gene Alias:
C1orf193; C1orf60; C77668; INT3; integrator complex subunit 3; Ints3; RGD1304593; Sensor of single-strand DNA complex subunit A; sensor of ssDNA subunit A; SOSS complex subunit A; SOSSA; SOSS-A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
229543, 361988, 65123

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q68E01, Q7TPD0

Gene Symbols:
INTS3

Immunogen:
A synthesized peptide derived from human INTS3(Accession Q68E01), corresponding to amino acid residues P503-R553.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100578

--


Antigen:
INTS8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
INTS8

Gene Alias:
C8orf52; FLJ20530; Int8; integrator complex subunit 8; INTS8; MGC131633; Protein kaonashi-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55656

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q75QN2

Gene Symbols:
INTS8

Immunogen:
A synthesized peptide derived from human INTS8(Accession Q75QN2), corresponding to amino acid residues C893-Y943.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100579

--


Antigen:
Importin 13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IPO13

Gene Alias:
Imp13; importin 13; importin-13; Ipo13; Kap13; karyopherin 13; karyopherin-13; KIAA0724; late gestation lung 2; late gestation lung 2 protein; LGL2; Ran binding protein 13; ran-binding protein 13; RanBP13; RP11-7O11.4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116458, 230673, 9670

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O94829, Q8K0C1, Q9JM04

Gene Symbols:
IPO13

Immunogen:
A synthesized peptide derived from human IPO13(Accession O94829), corresponding to amino acid residues A636-Q686.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100581

--


Antigen:
ITM2A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITM2A

Gene Alias:
AW108051; BRICD2A; BRICHOS domain containing 2A; E25; E25A; Integral membrane protein 2A; Itm2; ITM2A; Protein E25; UNQ603/PRO1189

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16431, 317218, 9452

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43736, Q61500

Gene Symbols:
ITM2A

Immunogen:
A synthesized peptide derived from human ITM2A(Accession O43736), corresponding to amino acid residues C73-I123.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG