PIPA5100646

NOXA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100646-Each-of-1 In Stock ₹ 44,705.10

PIPA5100646 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

NOXA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PMAIP1

Gene Alias

adult T cell leukemia-derived PMA-responsive; APR; Immediate-early-response protein APR; Noxa; Phorbol-12-myristate-13-acetate-induced protein 1; PMA-ind; PMA-induced protein 1; Pmaip1; Protein Noxa

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5366

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q13794

Gene Symbols

PMAIP1

Immunogen

A synthesized peptide derived from human PMAIP1(Accession Q13794), corresponding to amino acid residues M1-G33.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total NOXA
  • Apoptosis is related to many diseases and development
  • The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes including p53R2, p53AIP1, and PUMA
  • A new p53 target gene, Noxa, was recently identified, which encodes a protein belonging to the subfamily of BH3-only proapoptic proteins
  • Noxa and PUMA are both transcriptional targets of p53 and BH3-only proteins
  • X-ray irradiation increased p53-dependent Noxa mRNA and protein levels
  • Noxa, when ectopically expressed, interacted with anti-apoptotic Bcl-2 family members, resulting in the activation of caspase-9
  • Noxa, like PUMA, localized to mitochondria and induces apoptosis in response to p53
  • Noxa and PUMA may represent direct mediators of p53-induced apoptosis
  • Increased levels of p53 and its target gene Noxa was found in the impaired tumor development.

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Img

Thermo Scientific

PIPA5100646

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Antigen:
NOXA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PMAIP1

Gene Alias:
adult T cell leukemia-derived PMA-responsive; APR; Immediate-early-response protein APR; Noxa; Phorbol-12-myristate-13-acetate-induced protein 1; PMA-ind; PMA-induced protein 1; Pmaip1; Protein Noxa

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5366

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13794

Gene Symbols:
PMAIP1

Immunogen:
A synthesized peptide derived from human PMAIP1(Accession Q13794), corresponding to amino acid residues M1-G33.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100647

--


Antigen:
NPLOC4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPLOC4

Gene Alias:
AK129375; FLJ20657; homolog of yeast nuclear protein localization 4; KIAA1499; mKIAA1499; NPL4; NPL4 homolog, ubiquitin recognition factor; Nploc4; NPLOC4 ubiquitin recognition factor; nuclear protein localization 4 homolog; nuclear protein localization 4 homolog (S. cerevisiae); nuclear protein localization protein 4 homolog; Protein NPL4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140639, 217365, 55666

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P60670, Q8TAT6, Q9ES54

Gene Symbols:
NPLOC4

Immunogen:
A synthesized peptide derived from human NPLOC4(Accession Q8TAT6), corresponding to amino acid residues G173-V223.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100650

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Antigen:
Nucleobindin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUCB1

Gene Alias:
B230337F23Rik; Bone 63 kDa calcium-binding protein; C77483; CALNUC; MTEST82; NUC; Nucb; Nucb1; nucleobindin 1; nucleobindin-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18220, 4924

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q02818, Q02819

Gene Symbols:
NUCB1

Immunogen:
A synthesized peptide derived from human NUCB1(Accession Q02818), corresponding to amino acid residues H213-Q263.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100652

--


Antigen:
NUDT9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nudt9

Gene Alias:
1190002C07Rik; Adenosine diphosphoribose pyrophosphatase; ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ADP-ribose pyrophosphatase; ADP-ribose pyrophosphatase, mitochondrial; ADP-ribose pyrosphosphatase NUDT9; ADPR-PPase; AI462474; fu33g07; hypothetical protein LOC406661; mitochondrial ADP-ribose pyrophosphatase-like protein; nucleoside diphosphate linked moiety X-type motif 9; nucleoside diphosphate-linked moiety X motif 9; nudix (nucleoside diphosphate linked moiety X)-type motif 9; nudix hydrolase 9; nudix motif 9; nudix -type motif 9; nudix-type motif 9; NUDT10; Nudt9; PSEC0099; sb:cb392; UNQ3012/PRO9771; wu:fj16b09; wu:fu33g07; zgc:63924

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
305149, 53343, 74167

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q5XIG0, Q8BVU5, Q9BW91

Gene Symbols:
Nudt9

Immunogen:
A synthesized peptide derived from human NUDT9(Accession Q9BW91), corresponding to amino acid residues V89-L139.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG