PIPA5100723

ITGB3BP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5100723-Each-of-1 In Stock ₹ 44,705.10

PIPA5100723 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ITGB3BP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ITGB3BP

Gene Alias

4930471O16Rik; AU022583; beta 3 endonexin; beta-3-endonexin; beta3-endonexin; Cenpr; CENP-R; Centromere protein R; HSU37139; integrin beta 3 binding protein (beta3-endonexin); integrin beta-3-binding protein; integrin subunit beta 3 binding protein; Itgb3bp; Nrif3; Nuclear receptor-interacting factor 3; TAP20

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23421, 67733

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q13352, Q9CQ82

Gene Symbols

ITGB3BP

Immunogen

A synthesized peptide derived from human ITGB3BP(Accession Q13352), corresponding to amino acid residues T36-F86.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total CENPR
  • ITGB3BP is a transcription coregulator that can have both coactivator and corepressor functions
  • Isoform 1, but not other isoforms, is involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion
  • ITGB3BP acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1
  • It induces apoptosis in breast cancer cells, but not in other cancer cells, via a caspase-2 mediated pathway that involves mitochondrial membrane permeabilization but does not require other caspases
  • ITGB3BP may also act as an inhibitor of cyclin A-associated kinase
  • ITGB3BP may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5100723

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Antigen:
ITGB3BP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITGB3BP

Gene Alias:
4930471O16Rik; AU022583; beta 3 endonexin; beta-3-endonexin; beta3-endonexin; Cenpr; CENP-R; Centromere protein R; HSU37139; integrin beta 3 binding protein (beta3-endonexin); integrin beta-3-binding protein; integrin subunit beta 3 binding protein; Itgb3bp; Nrif3; Nuclear receptor-interacting factor 3; TAP20

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23421, 67733

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13352, Q9CQ82

Gene Symbols:
ITGB3BP

Immunogen:
A synthesized peptide derived from human ITGB3BP(Accession Q13352), corresponding to amino acid residues T36-F86.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100724

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Antigen:
CENPT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CENPT

Gene Alias:
C16orf56; CENPT; CENP-T; Centromere protein T; G630055P03Rik; ICEN22; Interphase centromere complex protein 22; RGD1309383

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
320394, 80152

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q3TJM4, Q96BT3

Gene Symbols:
CENPT

Immunogen:
A synthesized peptide derived from human CENPT(Accession Q96BT3), corresponding to amino acid residues P423-M473.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100725

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Antigen:
CENPU

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cenpu

Gene Alias:
1700029A22Rik; CENP50; CENP-50; Cenpu; CENP-U; CENPU50; Centromere protein of 50 kDa; centromere protein U; ICEN24; Interphase centromere complex protein 24; KLIP1; KSHV latent nuclear antigen interacting protein 1; KSHV latent nuclear antigen-interacting protein 1; LOC617866 protein; MLF1 interacting protein; MLF1-interacting protein; MLF1IP; myeloid leukemia factor 1 interacting protein; PBIP1; Polo-box-interacting protein 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
71876, 79682

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q71F23, Q8C4M7

Gene Symbols:
Cenpu

Immunogen:
A synthesized peptide derived from human CENPU(Accession Q71F23), corresponding to amino acid residues M1-G35.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100727

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Antigen:
CYLC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CYLC1

Gene Alias:
CYCL1; CYL; CYL1; CYLC1; cylicin; cylicin 1; cylicin I; cylicin, basic protein of sperm head cytoskeleton 1; cylicin-1; Multiple-band polypeptide I; rCG38076-like

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100359483, 1538, 67407

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P35663

Gene Symbols:
CYLC1

Immunogen:
A synthesized peptide derived from human CYLC1(Accession P35663), corresponding to amino acid residues V317-P367.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG