PIPA5101068

DKC1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5101068-Each-of-1 In Stock ₹ 44,705.10

PIPA5101068 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DKC1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DKC1

Gene Alias

BC068171; CBF5; CBF5 homolog; DKC; DKC1; DKCX; dyskeratosis congenita 1, dyskerin; dyskeratosis congenita 1, dyskerin homolog; dyskerin; dyskerin pseudouridine synthase 1; H/ACA ribonucleoprotein complex subunit 4; H/ACA ribonucleoprotein complex subunit DKC1; Nap57; NOLA4; Nopp140-associated protein of 57 kDa; nucleolar protein family A member 4; Nucleolar protein NAP57; snoRNP protein DKC1; XAP101

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

170944, 1736, 245474

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O60832, P40615, Q9ESX5

Gene Symbols

DKC1

Immunogen

A synthesized peptide derived from human DKC1(Accession O60832), corresponding to amino acid residues R183-L233.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total DKC1
  • This gene is a member of the H/ACA snoRNPs gene family
  • snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA
  • The H/ACA snoRNPs also include the NOLA1, 2 and 3 proteins
  • The protein encoded by this gene and the three NOLA proteins localize to the dense fibrillar components of nucleoli and to coiled bodies in the nucleus
  • Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted
  • These four H/ACA snoRNP proteins are also components of the telomerase complex
  • The protein encoded by this gene is related to the Saccharomyces cerevisiae Cbf5p and Drosophila melanogaster Nop60B proteins
  • The gene lies in a tail-to-tail orientation with the palmitoylated erythrocyte membrane protein gene and is transcribed in a telomere to centromere direction
  • Both nucleotide substitutions and single trinucleotide repeat polymorphisms have been found in this gene
  • Mutations in this gene cause X-linked dyskeratosis congenita, a disease resulting in reticulate skin pigmentation, mucosal leukoplakia, nail dystrophy, and progressive bone marrow failure in most cases
  • Mutations in this gene also cause Hoyeraal-Hreidarsson syndrome, which is a more severe form of dyskeratosis congenita
  • Two transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5101068

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Antigen:
DKC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DKC1

Gene Alias:
BC068171; CBF5; CBF5 homolog; DKC; DKC1; DKCX; dyskeratosis congenita 1, dyskerin; dyskeratosis congenita 1, dyskerin homolog; dyskerin; dyskerin pseudouridine synthase 1; H/ACA ribonucleoprotein complex subunit 4; H/ACA ribonucleoprotein complex subunit DKC1; Nap57; NOLA4; Nopp140-associated protein of 57 kDa; nucleolar protein family A member 4; Nucleolar protein NAP57; snoRNP protein DKC1; XAP101

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170944, 1736, 245474

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60832, P40615, Q9ESX5

Gene Symbols:
DKC1

Immunogen:
A synthesized peptide derived from human DKC1(Accession O60832), corresponding to amino acid residues R183-L233.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5101070

--


Antigen:
BERP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIM3

Gene Alias:
Berp; BERP1; brain expressed ring finger; brain-expressed RING finger protein; Hac1; RING finger protein 22; RING finger protein 97; RING finger protein HAC1; RNF22; RNF97; Trim3; tripartite motif containing 3; tripartite motif protein 3; tripartite motif protein TRIM3; tripartite motif-containing 3; tripartite motif-containing protein 3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10612, 55992, 83616

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O70277, O75382, Q9R1R2

Gene Symbols:
TRIM3

Immunogen:
A synthesized peptide derived from human TRIM3(Accession O75382), corresponding to amino acid residues V435-E485.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5101071

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Antigen:
SLC43A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC43A1

Gene Alias:
2610016F07Rik; AA986141; large neutral amino acids transporter small subunit 3; LAT3; L-type amino acid transporter 3; PB39; POV1; prostate cancer overexpressed gene 1; prostate cancer overexpressed gene 1 protein; R00504; Slc43a1; solute carrier family 43 (amino acid system L transporter), member 1; solute carrier family 43 member 1; solute carrier family 43, member 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
72401, 8501

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75387, Q8BSM7

Gene Symbols:
SLC43A1

Immunogen:
A synthesized peptide derived from human SLC43A1(Accession O75387), corresponding to amino acid residues V245-L295.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5101072

--


Antigen:
TACC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TACC1

Gene Alias:
4833447E04Rik; AA960202; B230378H13Rik; Ga55; gastric cancer antigen Ga55; KIAA1103; Tacc1; Tacc1a; Taxin-1; transforming acidic coiled-coil containing protein 1; transforming acidic coiled-coil-containing protein 1; transforming, acidic coiled-coil containing protein 1; transforming, acidic coiled-coil containing protein 1a

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
320165, 6867

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75410, Q6Y685

Gene Symbols:
TACC1

Immunogen:
A synthesized peptide derived from human TACC1(Accession O75410), corresponding to amino acid residues A21-R71.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG