PIPA5101132
MLLT10 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101132-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5101132 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MLLT10
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MLLT10
Gene Alias
Af10; af-10; ALL1-fused gene from chromosome 10 protein; B130021D15Rik; D630001B22Rik; DKFZp686E10210; MGC75086; mKIAA4140; MLLT10; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10; protein AF-10; translocated to, 10; type I AF10 protein; type III AF10 protein; type IV AF10 protein
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17354, 8028
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O54826, P55197
Gene Symbols
MLLT10
Immunogen
A synthesized peptide derived from human MLLT10(Accession P55197), corresponding to amino acid residues S217-Y267.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total AF10
- Translocations affecting chromosome 11q23 involve many partner chromosome regions and occur in various leukemias
- The 11q23 gene involved in the translocations is MLL
- MLLT10 is the partner gene to MLL1 involved in t(10;11)(p12;q23) translocations
- In an analysis of two leukemia patients, the in t(10;11)(p12;q23) translocation fuses MLL1, a SET domain containg histone methyltransferase, to the MLLT10 gene
- The MLLT10 gene encodes a predicted 1,027-amino acid protein containing an N-terminal zinc finger and a C-terminal leucine zipper domain
- The MLLT10 gene is one of the few MLL partner genes to be independently rearranged with a third gene in leukemia, the CALM gene in the t(10;11)(p12;q14) translocation
- Chimeric fusion proteins MLL/AF10 and CALM/AF10 consistently retain the leucine zipper motif of MLLT10
- The leucine zipper interacts with GAS41, a protein previously identified as the product of an amplified gene in a glioblastoma
- GAS41 interacts with integrase interactor-1 (INI1), a component of the SWI/SNF complex, which acts to remodel chromatin and to modulate transcription
- Retention of the leucine zipper in the MLL and CALM fusions suggested that a key feature of these chimeric proteins may be their ability to interfere in normal gene regulation through interaction with the adenosine triphosphate-dependent chromatin remodeling complexes.
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Antigen: MLLT10
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MLLT10
Gene Alias: Af10; af-10; ALL1-fused gene from chromosome 10 protein; B130021D15Rik; D630001B22Rik; DKFZp686E10210; MGC75086; mKIAA4140; MLLT10; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10; protein AF-10; translocated to, 10; type I AF10 protein; type III AF10 protein; type IV AF10 protein
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17354, 8028
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O54826, P55197
Gene Symbols: MLLT10
Immunogen: A synthesized peptide derived from human MLLT10(Accession P55197), corresponding to amino acid residues S217-Y267.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MLLT10
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MLLT10
Gene Alias:
Af10; af-10; ALL1-fused gene from chromosome 10 protein; B130021D15Rik; D630001B22Rik; DKFZp686E10210; MGC75086; mKIAA4140; MLLT10; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10; protein AF-10; translocated to, 10; type I AF10 protein; type III AF10 protein; type IV AF10 protein
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17354, 8028
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O54826, P55197
Gene Symbols:
MLLT10
Immunogen:
A synthesized peptide derived from human MLLT10(Accession P55197), corresponding to amino acid residues S217-Y267.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: ELL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ell
Gene Alias: C19orf17; Eleven-nineteen lysine-rich leukemia protein; Ell; ELL gene (11-19 lysine-rich leukemia gene); ELL1; elongation factor for RNA polymerase II; elongation factor RNA polymerase II; hypothetical protein LOC325221; MEN; PPP1R68; protein phosphatase 1, regulatory subunit 68; RNA polymerase II elongation factor ELL; RNA POLYMERASE II ELONGATION FACTOR ELL (ELEVEN-NINETEEN LYSINE-RICH LEUKEMIA PROTEIN); wu:fc60b11; zgc:63836
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13716, 8178
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O08856, P55199
Gene Symbols: Ell
Immunogen: A synthesized peptide derived from human ELL(Accession P55199), corresponding to amino acid residues E105-Y155.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ELL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ell
Gene Alias:
C19orf17; Eleven-nineteen lysine-rich leukemia protein; Ell; ELL gene (11-19 lysine-rich leukemia gene); ELL1; elongation factor for RNA polymerase II; elongation factor RNA polymerase II; hypothetical protein LOC325221; MEN; PPP1R68; protein phosphatase 1, regulatory subunit 68; RNA polymerase II elongation factor ELL; RNA POLYMERASE II ELONGATION FACTOR ELL (ELEVEN-NINETEEN LYSINE-RICH LEUKEMIA PROTEIN); wu:fc60b11; zgc:63836
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13716, 8178
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O08856, P55199
Gene Symbols:
Ell
Immunogen:
A synthesized peptide derived from human ELL(Accession P55199), corresponding to amino acid residues E105-Y155.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: LMO4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LMO4
Gene Alias: A730077C12Rik; Breast tumor autoantigen; Crp3; ethanol induced 4; Etohi4; LIM domain only 4; LIM domain only protein 4; LIM domain transcription factor LMO4; LIM-only 4 protein; LMO4; LMO-4
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16911, 362051, 8543
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P61968, P61969
Gene Symbols: LMO4
Immunogen: A synthesized peptide derived from human LMO4(Accession P61968), corresponding to amino acid residues C118-C165.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LMO4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LMO4
Gene Alias:
A730077C12Rik; Breast tumor autoantigen; Crp3; ethanol induced 4; Etohi4; LIM domain only 4; LIM domain only protein 4; LIM domain transcription factor LMO4; LIM-only 4 protein; LMO4; LMO-4
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16911, 362051, 8543
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P61968, P61969
Gene Symbols:
LMO4
Immunogen:
A synthesized peptide derived from human LMO4(Accession P61968), corresponding to amino acid residues C118-C165.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PITX1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PITX1
Gene Alias: BFT; CCF; hindlimb expressed homeobox protein backfoot; hindlimb-expressed homeobox protein backfoot; homeobox protein PITX1; Homeobox protein P-OTX; LBNBG; OTX; paired like homeodomain 1; paired-like homeodomain 1; paired-like homeodomain transcription factor 1; pituitary homeo box 1; pituitary homeobox 1; Pituitary OTX-related factor; Pitx1; Potx; P-OTX; PTX1; Unknown (protein for MGC:136976); zgc:136976
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 113983, 18740, 5307
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P70314, P78337, Q99NA7
Gene Symbols: PITX1
Immunogen: A synthesized peptide derived from human PITX1(Accession P78337), corresponding to amino acid residues R110-Y160.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PITX1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PITX1
Gene Alias:
BFT; CCF; hindlimb expressed homeobox protein backfoot; hindlimb-expressed homeobox protein backfoot; homeobox protein PITX1; Homeobox protein P-OTX; LBNBG; OTX; paired like homeodomain 1; paired-like homeodomain 1; paired-like homeodomain transcription factor 1; pituitary homeo box 1; pituitary homeobox 1; Pituitary OTX-related factor; Pitx1; Potx; P-OTX; PTX1; Unknown (protein for MGC:136976); zgc:136976
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
113983, 18740, 5307
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P70314, P78337, Q99NA7
Gene Symbols:
PITX1
Immunogen:
A synthesized peptide derived from human PITX1(Accession P78337), corresponding to amino acid residues R110-Y160.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG