PIPA5101168
p35 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101168-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5101168 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
p35
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cdk5r1
Gene Alias
23 kDa subunit of tau-protein kinase II; cdk5 activator; CDK5 activator 1; CDK5P35; Cdk5r; Cdk5r1; cyclin dependent kinase 5 regulatory subunit 1; cyclin-dependent kinase 5 activator 1; Cyclin-dependent kinase 5 activator 1, p25; Cyclin-dependent kinase 5 activator 1, p35; Cyclin-dependent kinase 5 regulatory subunit 1; cyclin-dependent kinase 5, regulatory subunit (p35) 1; cyclin-dependent kinase 5, regulatory subunit 1 (p35); D11Bwg0379e; NCK5A; neuronal CDK5 activator; p23; p25; P25/P35; p35; p35nck5a; regulatory partner for CDK5 kinase; tau protein kinase II 23 kDa subunit; tau protein kinase II 23kDa subunit; TPKII regulatory subunit
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116671, 12569, 8851
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P61809, P61810, Q15078
Gene Symbols
Cdk5r1
Immunogen
A synthesized peptide derived from human CDK5R1(Accession Q15078), corresponding to amino acid residues K13-K63.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total CDK5R1/P35
- The protein encoded by this gene (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5); the activation of CDK5 is required for proper development of the central nervous system
- The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form
- The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions
- P25 deregulates CDK5 activity by prolonging its activation and changing its cellular location
- The p25 form accumulates in the brain neurons of patients with Alzheimer's disease
- This accumulation correlates with an increase in CDK5 kinase activity, and may lead to aberrantly phosphorylated forms of the microtubule-associated protein tau, which contributes to Alzheimer's disease.
Compare Similar Items
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Antigen: p35
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cdk5r1
Gene Alias: 23 kDa subunit of tau-protein kinase II; cdk5 activator; CDK5 activator 1; CDK5P35; Cdk5r; Cdk5r1; cyclin dependent kinase 5 regulatory subunit 1; cyclin-dependent kinase 5 activator 1; Cyclin-dependent kinase 5 activator 1, p25; Cyclin-dependent kinase 5 activator 1, p35; Cyclin-dependent kinase 5 regulatory subunit 1; cyclin-dependent kinase 5, regulatory subunit (p35) 1; cyclin-dependent kinase 5, regulatory subunit 1 (p35); D11Bwg0379e; NCK5A; neuronal CDK5 activator; p23; p25; P25/P35; p35; p35nck5a; regulatory partner for CDK5 kinase; tau protein kinase II 23 kDa subunit; tau protein kinase II 23kDa subunit; TPKII regulatory subunit
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116671, 12569, 8851
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P61809, P61810, Q15078
Gene Symbols: Cdk5r1
Immunogen: A synthesized peptide derived from human CDK5R1(Accession Q15078), corresponding to amino acid residues K13-K63.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
p35
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cdk5r1
Gene Alias:
23 kDa subunit of tau-protein kinase II; cdk5 activator; CDK5 activator 1; CDK5P35; Cdk5r; Cdk5r1; cyclin dependent kinase 5 regulatory subunit 1; cyclin-dependent kinase 5 activator 1; Cyclin-dependent kinase 5 activator 1, p25; Cyclin-dependent kinase 5 activator 1, p35; Cyclin-dependent kinase 5 regulatory subunit 1; cyclin-dependent kinase 5, regulatory subunit (p35) 1; cyclin-dependent kinase 5, regulatory subunit 1 (p35); D11Bwg0379e; NCK5A; neuronal CDK5 activator; p23; p25; P25/P35; p35; p35nck5a; regulatory partner for CDK5 kinase; tau protein kinase II 23 kDa subunit; tau protein kinase II 23kDa subunit; TPKII regulatory subunit
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116671, 12569, 8851
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P61809, P61810, Q15078
Gene Symbols:
Cdk5r1
Immunogen:
A synthesized peptide derived from human CDK5R1(Accession Q15078), corresponding to amino acid residues K13-K63.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CDK10
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDK10
Gene Alias: BC017131; CDC2-related protein kinase; Cdk10; Cell division protein kinase 10; cyclin dependent kinase 10; cyclin-dependent kinase (CDC2-like) 10; cyclin-dependent kinase 10; cyclin-dependent kinase related protein; PISSLRE; serine/threonine protein kinase PISSLRE; serine/threonine-protein kinase PISSLRE
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 234854, 361434, 8558
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q15131, Q3UMM4, Q4KM47
Gene Symbols: CDK10
Immunogen: A synthesized peptide derived from human CDK10(Accession Q15131), corresponding to amino acid residues N43-L93.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CDK10
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDK10
Gene Alias:
BC017131; CDC2-related protein kinase; Cdk10; Cell division protein kinase 10; cyclin dependent kinase 10; cyclin-dependent kinase (CDC2-like) 10; cyclin-dependent kinase 10; cyclin-dependent kinase related protein; PISSLRE; serine/threonine protein kinase PISSLRE; serine/threonine-protein kinase PISSLRE
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
234854, 361434, 8558
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q15131, Q3UMM4, Q4KM47
Gene Symbols:
CDK10
Immunogen:
A synthesized peptide derived from human CDK10(Accession Q15131), corresponding to amino acid residues N43-L93.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TAF5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TAF5
Gene Alias: 6330528C20Rik; AV117817; TAF(II)100; TAF2D; TAF5; TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa; TAFII100; TAFII-100; TATA box binding protein (TBP)-associated factor 2D; TATA box binding protein (TBP)-associated factor, RNA polymerase II, D, 100kD; TATA box binding protein associated factor 5; TATA-box binding protein associated factor 5; Tbp-associated factor 5; transcription initiation factor TFIID 100 kD subunit; transcription initiation factor TFIID 100 kDa subunit; Transcription initiation factor TFIID subunit 5
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 226182, 6877
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q15542, Q8C092
Gene Symbols: TAF5
Immunogen: A synthesized peptide derived from human TAF5(Accession Q15542), corresponding to amino acid residues E391-I441.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TAF5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TAF5
Gene Alias:
6330528C20Rik; AV117817; TAF(II)100; TAF2D; TAF5; TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa; TAFII100; TAFII-100; TATA box binding protein (TBP)-associated factor 2D; TATA box binding protein (TBP)-associated factor, RNA polymerase II, D, 100kD; TATA box binding protein associated factor 5; TATA-box binding protein associated factor 5; Tbp-associated factor 5; transcription initiation factor TFIID 100 kD subunit; transcription initiation factor TFIID 100 kDa subunit; Transcription initiation factor TFIID subunit 5
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
226182, 6877
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q15542, Q8C092
Gene Symbols:
TAF5
Immunogen:
A synthesized peptide derived from human TAF5(Accession Q15542), corresponding to amino acid residues E391-I441.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TAF1A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TAF1A
Gene Alias: MGC:17061; mTAFI48; RAFI48; RNA polymerase I-specific TBP-associated factor 48 kDa; similar to TBP-associated factor 1A isoform 1; SL1; SL1, 48kD subunit; Taf1a; TAFI48; TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa; TATA box binding protein associated factor 1A; TATA box binding protein-associated factor TAF1A; TATA box-binding protein-associated factor 1A; TATA box-binding protein-associated factor RNA polymerase I subunit A; TATA-box binding protein associated factor, RNA polymerase I subunit A; TATA-box binding protein associated factor, RNA polymerase I, A; TBP-associated factor 1A; Transcription factor SL1; transcription initiation factor SL1/TIF-IB subunit A
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21339, 360893, 9015
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P97357, Q15573, Q3B7U2
Gene Symbols: TAF1A
Immunogen: A synthesized peptide derived from human TAF1A(Accession Q15573), corresponding to amino acid residues K298-A348.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TAF1A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TAF1A
Gene Alias:
MGC:17061; mTAFI48; RAFI48; RNA polymerase I-specific TBP-associated factor 48 kDa; similar to TBP-associated factor 1A isoform 1; SL1; SL1, 48kD subunit; Taf1a; TAFI48; TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa; TATA box binding protein associated factor 1A; TATA box binding protein-associated factor TAF1A; TATA box-binding protein-associated factor 1A; TATA box-binding protein-associated factor RNA polymerase I subunit A; TATA-box binding protein associated factor, RNA polymerase I subunit A; TATA-box binding protein associated factor, RNA polymerase I, A; TBP-associated factor 1A; Transcription factor SL1; transcription initiation factor SL1/TIF-IB subunit A
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21339, 360893, 9015
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P97357, Q15573, Q3B7U2
Gene Symbols:
TAF1A
Immunogen:
A synthesized peptide derived from human TAF1A(Accession Q15573), corresponding to amino acid residues K298-A348.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG