PIPA5101199

MAP4K3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5101199-Each-of-1 In Stock ₹ 43,592.82

PIPA5101199 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

MAP4K3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP4K3

Gene Alias

4833416M01Rik; 4833416M07Rik; 9530052P13Rik; germinal center kinase-like kinase; germinal center kinase-related protein kinase; GLK; MAP4K3; MAPK/ERK kinase kinase kinase 3; MAPKKKK3; MEK kinase kinase 3; MEKKK 3; MEKKK3; mitogen activated protein kinase kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase kinase 3; RAB8IPL1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

170920, 225028, 8491

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8IVH8, Q924I2, Q99JP0

Gene Symbols

MAP4K3

Immunogen

A synthesized peptide derived from human MAP4K3(Accession Q8IVH8), corresponding to amino acid residues M1-R34.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total MAP4K3
  • MAP4K3 (also known as GLK) is a member of the STE20 family of serine/threonine protein kinases and contains N-terminal catalytic domain and C-terminal regulatory domain
  • MAP4K3 is upstream of the MEKK1 target and is stimulated by UV radiation and TNF-alpha and can lead to the activation of the JNK signaling pathway
  • MAP4K3 can directly activate PKC-T, during TCR signaling and people with systemic lupus erythematosus show considerable enhanced MAP4K3 expression and activation of PKC-T, and the kinase IKK in T cells
  • MAP4K3 can act as a pro-apoptotic kinase which orchestrates activation of BAX via the concerted posttranscriptional modulation of PUMA, BAD, and BIM
  • The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha
  • The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway
  • Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase 1 (MEKK1)
  • MAP4K3 previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase 3 (MAP4K3).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5101199

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Antigen:
MAP4K3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP4K3

Gene Alias:
4833416M01Rik; 4833416M07Rik; 9530052P13Rik; germinal center kinase-like kinase; germinal center kinase-related protein kinase; GLK; MAP4K3; MAPK/ERK kinase kinase kinase 3; MAPKKKK3; MEK kinase kinase 3; MEKKK 3; MEKKK3; mitogen activated protein kinase kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase kinase 3; RAB8IPL1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170920, 225028, 8491

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8IVH8, Q924I2, Q99JP0

Gene Symbols:
MAP4K3

Immunogen:
A synthesized peptide derived from human MAP4K3(Accession Q8IVH8), corresponding to amino acid residues M1-R34.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101201

--


Antigen:
FUK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FUK

Gene Alias:
1110046B12Rik; AI303278; Fcsk; Fucokinase; FUK; L-fucose kinase; mFLJ00241 protein; UNQ5838

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
197258, 234730

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q7TMC8, Q8N0W3

Gene Symbols:
FUK

Immunogen:
A synthesized peptide derived from human FUK(Accession Q8N0W3), corresponding to amino acid residues G6-S56.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101202

--


Antigen:
DBC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCAR2

Gene Alias:
2610301G19Rik; bA574M5.1 (deleted in bladder cancer chromosome region candidate 1 (IB3089A)); BMP/retinoic acid inducible neural specific 1; BMP/retinoic acid-inducible neural-specific protein (BRINP); BMP/retinoic acid-inducible neural-specific protein 1; BMP/retinoic acid-inducible neural-specific protein-1; bone morphogenetic protein/retinoic acid inducible neural-specific 1; bone morphogenic protein/retinoic acid inducible neural specific 1; bone morphogenic protein/retinoic acid inducible neural-specific 1; BRINP; Brinp1; Ccar2; cell cycle activator and apoptosis regulator 2; cell cycle and apoptosis regulator 2; cell cycle and apoptosis regulator protein 2; Cell division cycle and apoptosis regulator protein 2; DBC.1; Dbc1; DBC-1; Dbccr1; DBIRD complex subunit KIAA1967; deleted in bladder cancer 1; deleted in bladder cancer chromosome region candidate 1; deleted in bladder cancer protein 1; Deleted in bladder cancer protein 1 homolog; deleted in breast cancer 1; Deleted in breast

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57805

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8N163

Gene Symbols:
CCAR2

Immunogen:
A synthesized peptide derived from human CCAR2(Accession Q8N163), corresponding to amino acid residues T435-P485.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101204

--


Antigen:
HIPK4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HIPK4

Gene Alias:
Gm162; Hipk4; homeodomain interacting protein kinase 4; homeodomain-interacting protein kinase 4; LOW QUALITY PROTEIN: homeodomain-interacting protein kinase 4; testicular tissue protein Li 87

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
147746, 233020, 308449

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q3V016, Q4V793, Q8NE63

Gene Symbols:
HIPK4

Immunogen:
A synthesized peptide derived from human HIPK4(Accession Q8NE63), corresponding to amino acid residues G570-H616.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG