BRF1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101229-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5101229 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
BRF1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BRF1
Gene Alias
2510002F24Rik; B - related factor 1; Berg36; B-related factor 1; BRF; BRF1; BRF-1; BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB; BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae); BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit; BRF1, RNA polymerase III transcription initiation factor 90 subunit; butyrate response factor 1; CFDS; cMG1; early response factor Berg36; EGF-response factor 1; epididymis secretory sperm binding protein Li 76p; ERF1; ERF-1; general transcription factor IIIB, 90kD subunit; GTF3B; hBRF; HEL-S-76p; hTFIIIB90; mRNA decay activator protein ZFP36L1; mTFIIIB90; RNF162B; TAF3B2; TAF3C; TAFIII90; TATA box binding protein (TBP)-associated factor 3C; TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2; TATA box-binding protein-associated factor, RNA polymerase III, subunit 2; TBP - associated factor, RNA polymerase III, 90kD; TF3B9
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2972, 72308
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q8CFK2, Q92994
Gene Symbols
BRF1
Immunogen
A synthesized peptide derived from human BRF1(Accession Q92994), corresponding to amino acid residues A418-R468.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total BRF1
- RNA polymerase (pol) III synthesizes tRNA, 5s rRNA, 7SL RNA and U6 snRNA and is overexpressed in many transformed cell lines and tumors in vivo, since cells must duplicate its protein components before division
- Therefore, in order to maintain rapid growth, cells must produce a high level of Pol III transcribed RNA, which requires the presence of the TFIIIB and TFIIIC2 transcription factor complexes
- The TFIIIC2 complex is composed of five subunits, TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, that are overexpressed in adenovirus transformed cells as well as in malignant cells in vivo, such as ovarian carcinomas
- TFIIIC2 recruits RNA pol III and TFIIIB to promoter elements and may be a key component in the deregulation of malignant cells
- The TFIIIB complex includes the TATA-binding protein (TBP), TFIIB-related factor 1 (TFIIIB90, BRF1) and TFIIIB, the expression of which are also upregulated in transformed cells
- In many carcinomas, the tumor suppressors retinoblastoma (RB) and p53 are inactivated, which affects their ability to bind and inactivate the function of TFIIIB.
Compare Similar Items
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Antigen: BRF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BRF1
Gene Alias: 2510002F24Rik; B - related factor 1; Berg36; B-related factor 1; BRF; BRF1; BRF-1; BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB; BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae); BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit; BRF1, RNA polymerase III transcription initiation factor 90 subunit; butyrate response factor 1; CFDS; cMG1; early response factor Berg36; EGF-response factor 1; epididymis secretory sperm binding protein Li 76p; ERF1; ERF-1; general transcription factor IIIB, 90kD subunit; GTF3B; hBRF; HEL-S-76p; hTFIIIB90; mRNA decay activator protein ZFP36L1; mTFIIIB90; RNF162B; TAF3B2; TAF3C; TAFIII90; TATA box binding protein (TBP)-associated factor 3C; TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2; TATA box-binding protein-associated factor, RNA polymerase III, subunit 2; TBP - associated factor, RNA polymerase III, 90kD; TF3B9
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2972, 72308
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q8CFK2, Q92994
Gene Symbols: BRF1
Immunogen: A synthesized peptide derived from human BRF1(Accession Q92994), corresponding to amino acid residues A418-R468.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen: CNKSR1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CNKSR1
Gene Alias: BC037758; CNK; CNK homolog protein 1; CNK1; CNKSR1; Connector enhancer of kinase suppressor of ras 1; connector enhancer of KSR 1; Connector enhancer of KSR-like
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10256, 194231, 298545
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q969H4
Gene Symbols: CNKSR1
Immunogen: A synthesized peptide derived from human CNKSR1(Accession Q969H4), corresponding to amino acid residues L350-E400.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen: PGBD1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PGBD1
Gene Alias: 4921509E05Rik; Cerebral protein 4; cerebral protein-4; dJ874C20.4; hucep-4; PGBD1; piggyBac transposable element derived 1; piggyBac transposable element-derived protein 1; SCAND4
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 84547
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q96JS3
Gene Symbols: PGBD1
Immunogen: A synthesized peptide derived from human PGBD1(Accession Q96JS3), corresponding to amino acid residues E249-S299.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
