PIPA5101252
YTHDF1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101252-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5101252 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
YTHDF1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
YTHDF1
Gene Alias
2210410K23Rik; 8030473O16; C20orf21; DACA-1; DACA-1 homolog; Dermatomyositis associated with cancer putative autoantigen 1; dermatomyositis associated with cancer putative autoantigen 1 homolog; fb49c02; wu:fb49c02; wu:fi19h06; wu:fj87f09; wu:fp06c11; YTH domain family 1; YTH domain family protein 1; YTH domain family, member 1; YTH domain-containing family protein 1; YTH N(6)-methyladenosine RNA binding protein 1; YTH N6-methyladenosine RNA binding protein 1; Ythdf1; zgc:55657
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
228994, 296467, 54915
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P59326, Q9BYJ9
Gene Symbols
YTHDF1
Immunogen
A synthesized peptide derived from human YTHDF1(Accession Q9BYJ9), corresponding to amino acid residues M1-Y37.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total YTHDF1
- Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451)
- M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625)
- Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440)
- Required to facilitate learning and memory formation in the hippocampus by enhancing protein synthesis upon neuronal stimulation: in response to neuronal stimulation, binds to m6A-containing neuronal mRNAs, promoting their translation, thereby contributing to learning and memory
- Acts as a regulator of axon guidance by binding to m6A-containing ROBO3 transcripts, thereby promoting their translation
- Acts as a negative regulator of antigen cross-presentation in myeloid dendritic cells
- Acts by binding and promoting translation of m6A-containing transcripts encoding proteins involved in lysosomal degradation and phagosome maturation, leading to increased antigen degradation in myeloid dendritic cells
- In the context of tumorigenesis, negative regulation of antigen cross-presentation limits the anti-tumor response by reducing efficiency of tumor-antigen cross-presentation
- [UniProt]
Compare Similar Items
Show Difference
Antigen: YTHDF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: YTHDF1
Gene Alias: 2210410K23Rik; 8030473O16; C20orf21; DACA-1; DACA-1 homolog; Dermatomyositis associated with cancer putative autoantigen 1; dermatomyositis associated with cancer putative autoantigen 1 homolog; fb49c02; wu:fb49c02; wu:fi19h06; wu:fj87f09; wu:fp06c11; YTH domain family 1; YTH domain family protein 1; YTH domain family, member 1; YTH domain-containing family protein 1; YTH N(6)-methyladenosine RNA binding protein 1; YTH N6-methyladenosine RNA binding protein 1; Ythdf1; zgc:55657
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 228994, 296467, 54915
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P59326, Q9BYJ9
Gene Symbols: YTHDF1
Immunogen: A synthesized peptide derived from human YTHDF1(Accession Q9BYJ9), corresponding to amino acid residues M1-Y37.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
YTHDF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
YTHDF1
Gene Alias:
2210410K23Rik; 8030473O16; C20orf21; DACA-1; DACA-1 homolog; Dermatomyositis associated with cancer putative autoantigen 1; dermatomyositis associated with cancer putative autoantigen 1 homolog; fb49c02; wu:fb49c02; wu:fi19h06; wu:fj87f09; wu:fp06c11; YTH domain family 1; YTH domain family protein 1; YTH domain family, member 1; YTH domain-containing family protein 1; YTH N(6)-methyladenosine RNA binding protein 1; YTH N6-methyladenosine RNA binding protein 1; Ythdf1; zgc:55657
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
228994, 296467, 54915
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P59326, Q9BYJ9
Gene Symbols:
YTHDF1
Immunogen:
A synthesized peptide derived from human YTHDF1(Accession Q9BYJ9), corresponding to amino acid residues M1-Y37.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PBOV1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PBOV1
Gene Alias: dJ171N11.2; PBOV1; prostate and breast cancer overexpressed 1; prostate and breast cancer overexpressed gene 1 protein; Protein UROC28; UC28; UROC28
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 59351
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9GZY1
Gene Symbols: PBOV1
Immunogen: A synthesized peptide derived from human PBOV1(Accession Q9GZY1), corresponding to amino acid residues F32-T82.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PBOV1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PBOV1
Gene Alias:
dJ171N11.2; PBOV1; prostate and breast cancer overexpressed 1; prostate and breast cancer overexpressed gene 1 protein; Protein UROC28; UC28; UROC28
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
59351
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9GZY1
Gene Symbols:
PBOV1
Immunogen:
A synthesized peptide derived from human PBOV1(Accession Q9GZY1), corresponding to amino acid residues F32-T82.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ZNF541
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZNF541
Gene Alias: Zfp541; Zinc finger protein 541; ZNF541
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 84215
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9H0D2
Gene Symbols: ZNF541
Immunogen: A synthesized peptide derived from human ZNF541(Accession Q9H0D2), corresponding to amino acid residues S917-A967.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ZNF541
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZNF541
Gene Alias:
Zfp541; Zinc finger protein 541; ZNF541
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
84215
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9H0D2
Gene Symbols:
ZNF541
Immunogen:
A synthesized peptide derived from human ZNF541(Accession Q9H0D2), corresponding to amino acid residues S917-A967.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: XRN2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Xrn2
Gene Alias: 5'-3' exoribonuclease 2; Dhm1; DHM1-like protein; DHP protein; Protein Dhm1; Xrn2; XRN2b
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22803, 24128
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9DBR1, Q9H0D6
Gene Symbols: Xrn2
Immunogen: A synthesized peptide derived from human XRN2(Accession Q9H0D6), corresponding to amino acid residues V92-K142.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
XRN2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Xrn2
Gene Alias:
5'-3' exoribonuclease 2; Dhm1; DHM1-like protein; DHP protein; Protein Dhm1; Xrn2; XRN2b
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22803, 24128
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9DBR1, Q9H0D6
Gene Symbols:
Xrn2
Immunogen:
A synthesized peptide derived from human XRN2(Accession Q9H0D6), corresponding to amino acid residues V92-K142.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG