PIPA5101297
CDCA2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101297-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5101297 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
CDCA2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDCA2
Gene Alias
2610311M19Rik; AI586158; CDCA2; cell division cycle associated 2; cell division cycle-associated protein 2; FLJ25804; MGC129906; MGC129907; PPP1R81; protein phosphatase 1, regulatory subunit 81; recruits PP1 onto mitotic chromatin at anaphase protein; Repo-Man
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
108912, 157313, 305984
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q14B71, Q69YH5
Gene Symbols
CDCA2
Immunogen
A synthesized peptide derived from human CDCA2(Accession Q69YH5), corresponding to amino acid residues L513-R563.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total CDCA2
- Cell division cycle associated 2 (CDCA2, Repo-Man) is a cell-cycle protein that recruits protein phosphatase 1 (PP1) to mitotic chromatin at anaphase onset, which is essential for cell proliferation
- Carboxy-terminal phosphorylation of CDCA2 at Ser893 by Aurora B inhibits the protein and leads to diffuse localization during prometaphase and metaphase
- Dephosphorylation of CDCA2 by PP2A is necessary for CDCA2/PP1 complex reformation
- The CDCA2/PP1 complex is required for chromatin binding and dephosphorylation of histone H3 at Thr3, Ser10, and Ser28
- The CDCA2/PP1 complex is also involved in nuclear envelope reformation during mitotic exit for proper progression through the M/G1 transition
- The interaction of CDCA2 with importin beta and Nup153, which is required for nuclear envelope formation, is negatively regulated by CDK phosphorylation of the amino-terminal domain of CDCA2
- CDCA2 may play a role in DNA repair as the release of CDCA2 from chromatin at sites of DNA damage promotes the activation of DNA damage response
- These results imply that the CDCA2/PP1 complex may play a part in cancer progression
- Research studies indicate that CDCA2 may serve as a prognostic marker, as increased CDCA2 expression is seen in a number of cancers, including melanoma, neuroblastoma tumors, squamous cell carcinoma, and synovial sarcomas.
Compare Similar Items
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Antigen: CDCA2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDCA2
Gene Alias: 2610311M19Rik; AI586158; CDCA2; cell division cycle associated 2; cell division cycle-associated protein 2; FLJ25804; MGC129906; MGC129907; PPP1R81; protein phosphatase 1, regulatory subunit 81; recruits PP1 onto mitotic chromatin at anaphase protein; Repo-Man
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 108912, 157313, 305984
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q14B71, Q69YH5
Gene Symbols: CDCA2
Immunogen: A synthesized peptide derived from human CDCA2(Accession Q69YH5), corresponding to amino acid residues L513-R563.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CDCA2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDCA2
Gene Alias:
2610311M19Rik; AI586158; CDCA2; cell division cycle associated 2; cell division cycle-associated protein 2; FLJ25804; MGC129906; MGC129907; PPP1R81; protein phosphatase 1, regulatory subunit 81; recruits PP1 onto mitotic chromatin at anaphase protein; Repo-Man
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
108912, 157313, 305984
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q14B71, Q69YH5
Gene Symbols:
CDCA2
Immunogen:
A synthesized peptide derived from human CDCA2(Accession Q69YH5), corresponding to amino acid residues L513-R563.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CDCA3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDCA3
Gene Alias: 2410005A12Rik; C8; CDCA 3; CDCA3; cell division cycle associated 3; cell division cycle-associated protein 3; gene rich cluster, C8; gene-rich cluster protein C8; GRCC 8; GRCC8; MGC2577; TOME 1; Tome1; TOME-1; trigger of mitotic entry 1; trigger of mitotic entry protein 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14793, 297594, 83461
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q68FW2, Q99618, Q99M54
Gene Symbols: CDCA3
Immunogen: A synthesized peptide derived from human CDCA3(Accession Q99618), corresponding to amino acid residues L231-S268.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CDCA3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDCA3
Gene Alias:
2410005A12Rik; C8; CDCA 3; CDCA3; cell division cycle associated 3; cell division cycle-associated protein 3; gene rich cluster, C8; gene-rich cluster protein C8; GRCC 8; GRCC8; MGC2577; TOME 1; Tome1; TOME-1; trigger of mitotic entry 1; trigger of mitotic entry protein 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14793, 297594, 83461
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q68FW2, Q99618, Q99M54
Gene Symbols:
CDCA3
Immunogen:
A synthesized peptide derived from human CDCA3(Accession Q99618), corresponding to amino acid residues L231-S268.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CDCA7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDCA7
Gene Alias: 2310021G01Rik; AU044109; CDCA7; cell division cycle associated 7; cell division cycle-associated protein 7; c-Myc target JPO1; ICF3; JPO1; Protein JPO1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 311742, 66953, 83879
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q4KM91, Q9BWT1, Q9D0M2
Gene Symbols: CDCA7
Immunogen: A synthesized peptide derived from human CDCA7(Accession Q9BWT1), corresponding to amino acid residues R146-M196.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CDCA7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDCA7
Gene Alias:
2310021G01Rik; AU044109; CDCA7; cell division cycle associated 7; cell division cycle-associated protein 7; c-Myc target JPO1; ICF3; JPO1; Protein JPO1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
311742, 66953, 83879
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q4KM91, Q9BWT1, Q9D0M2
Gene Symbols:
CDCA7
Immunogen:
A synthesized peptide derived from human CDCA7(Accession Q9BWT1), corresponding to amino acid residues R146-M196.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: COL13A1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: COL13A1
Gene Alias: CMS19; COL13A1; Collagen alpha-1(XIII) chain; collagen type XIII alpha 1 chain; collagen, type XIII, alpha 1; COLXIIIA1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12817, 1305
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q5TAT6, Q9R1N9
Gene Symbols: COL13A1
Immunogen: A synthesized peptide derived from human COL13A1(Accession Q5TAT6), corresponding to amino acid residues P651-P701.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
COL13A1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
COL13A1
Gene Alias:
CMS19; COL13A1; Collagen alpha-1(XIII) chain; collagen type XIII alpha 1 chain; collagen, type XIII, alpha 1; COLXIIIA1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12817, 1305
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q5TAT6, Q9R1N9
Gene Symbols:
COL13A1
Immunogen:
A synthesized peptide derived from human COL13A1(Accession Q5TAT6), corresponding to amino acid residues P651-P701.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG