PIPA5101324

FRS3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5101324-Each-of-1 In Stock ₹ 44,705.10

PIPA5101324 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

FRS3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FRS3

Gene Alias

4930417B13Rik; AI449674; FGFR substrate 3; FGFR-signaling adaptor SNT2; Fibroblast growth factor receptor substrate 3; FRS2B; Frs2beta; FRS2-beta; FRS3; Snt2; SNT-2; Suc1-associated neurotrophic factor target 2; suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor); testicular tissue protein Li 71

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10817

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O43559

Gene Symbols

FRS3

Immunogen

A synthesized peptide derived from human FRS3(Accession O43559), corresponding to amino acid residues E199-A249.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total SNT2
  • FRS3 (fibroblast growth factor receptor substrate 3), also known as FRS2B (FRS2-beta), is a 492 amino acid lipid-anchor adapter protein that contains one IRS-type PTB domain
  • Colocalizing to neural tissues with Tuj1, FRS3 functions as a feedback inhibitor of EGFR family members by preventing heterodimer formation between EGFR and ErbB2, thereby acting as a potential tumor suppressor
  • FRS3 is phosphorylated upon stimulation by FGF-2 or NGF and, acting as an adapter protein, links c-Fgr and NGF receptors to downstream signaling pathways
  • Interfering with the phosphorylation and nuclear translocation of ERK-2, FRS3 down-regulates ERK-2 expression
  • FRS3 likely interacts directly with GRB2, SH-PTP2, Flg, and Trk A, and may be involved in MAP kinase activation.

Compare Similar Items

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Img

Thermo Scientific

PIPA5101324

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Antigen:
FRS3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FRS3

Gene Alias:
4930417B13Rik; AI449674; FGFR substrate 3; FGFR-signaling adaptor SNT2; Fibroblast growth factor receptor substrate 3; FRS2B; Frs2beta; FRS2-beta; FRS3; Snt2; SNT-2; Suc1-associated neurotrophic factor target 2; suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor); testicular tissue protein Li 71

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10817

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43559

Gene Symbols:
FRS3

Immunogen:
A synthesized peptide derived from human FRS3(Accession O43559), corresponding to amino acid residues E199-A249.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101325

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Antigen:
GRID1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRID1

Gene Alias:
GluD1; gluR delta-1 subunit; GluRdelta1; glutamate ionotropic receptor delta type subunit 1; glutamate receptor; glutamate receptor delta-1 subunit; glutamate receptor ionotropic, delta-1; glutamate receptor, ionotropic, delta 1; GRID1; KIAA1220

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14803, 2894, 79219

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q61627, Q62640, Q9ULK0

Gene Symbols:
GRID1

Immunogen:
A synthesized peptide derived from human GRID1(Accession Q9ULK0), corresponding to amino acid residues I396-E446.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101328

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Antigen:
Bcl-W

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCL2L2

Gene Alias:
Apoptosis regulator Bcl-W; AW048834; BCL2 like 2; BCL2L2; BCL2-L-2; BCL2-like 2; BCL2-like 2 protein; Bcl-2-like protein 2; Bcl2-like protein 2; BCLW; BCL-W; BCL-WEL; BCL-WS; c98; Gtrgal2; Gtrosa41; Kiaa0271; PPP1R51; protein phosphatase 1, regulatory subunit 51

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12050, 599, 60434

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P70345, Q92843

Gene Symbols:
BCL2L2

Immunogen:
A synthesized peptide derived from human BCL2L2(Accession Q92843), corresponding to amino acid residues V18-L68.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101329

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Antigen:
CIDEB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CIDEB

Gene Alias:
1110030C18Rik; AI790179; Cell death activator CIDE-B; cell death-inducing DFFA-like effector B; cell death-inducing DNA fragmentation factor, alpha subunit-like effector B; CID; Cideb; CIDE-B; DFFA-like B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12684, 27141

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O70303, Q9UHD4

Gene Symbols:
CIDEB

Immunogen:
A synthesized peptide derived from human CIDEB(Accession Q9UHD4), corresponding to amino acid residues T97-F147.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG