PIPA5101505
LYAR Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101505-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5101505 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
LYAR
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LYAR
Gene Alias
apoptosis-related protein; cell growth-regulating nucleolar protein; hypothetical protein FLJ20425; Ly1 antibody reactive; Ly1 antibody reactive clone; Ly1 antibody reactive homolog; Ly1 antibody-reactive protein; Lyar; LYAR protein; MLZ-264; PNAS-5; protein expressed in male leptotene and zygotene spermatocytes 264; ZC2HC2; ZLYAR
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17089, 55646
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q08288, Q9NX58
Gene Symbols
LYAR
Immunogen
A synthesized peptide derived from human LYAR(Accession Q9NX58), corresponding to amino acid residues K250-D300.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total LYAR
- Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (PubMed:24495227)
- Also acts at the level of transcription regulation
- Along with PRMT5, binds the gamma-globin (HBG1/HBG2) promoter and represses its expression (PubMed:25092918)
- In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and SNORD41 that encodes a small nucleolar RNA (PubMed:28686580)
- Preferentially binds to a DNA motif containing 5'-GGTTAT-3' (PubMed:25092918)
- Negatively regulates the antiviral innate immune response by targeting IRF3 and impairing its DNA-binding activity (PubMed:31413131)
- In addition, inhibits NF-kappa-B-mediated expression of proinflammatory cytokines (PubMed:31413131)
- Stimulates phagocytosis of photoreceptor outer segments by retinal pigment epithelial cells
- Prevents nucleolin/NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal
- [UniProt]
Compare Similar Items
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Antigen: LYAR
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LYAR
Gene Alias: apoptosis-related protein; cell growth-regulating nucleolar protein; hypothetical protein FLJ20425; Ly1 antibody reactive; Ly1 antibody reactive clone; Ly1 antibody reactive homolog; Ly1 antibody-reactive protein; Lyar; LYAR protein; MLZ-264; PNAS-5; protein expressed in male leptotene and zygotene spermatocytes 264; ZC2HC2; ZLYAR
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17089, 55646
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q08288, Q9NX58
Gene Symbols: LYAR
Immunogen: A synthesized peptide derived from human LYAR(Accession Q9NX58), corresponding to amino acid residues K250-D300.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
LYAR
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LYAR
Gene Alias:
apoptosis-related protein; cell growth-regulating nucleolar protein; hypothetical protein FLJ20425; Ly1 antibody reactive; Ly1 antibody reactive clone; Ly1 antibody reactive homolog; Ly1 antibody-reactive protein; Lyar; LYAR protein; MLZ-264; PNAS-5; protein expressed in male leptotene and zygotene spermatocytes 264; ZC2HC2; ZLYAR
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17089, 55646
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q08288, Q9NX58
Gene Symbols:
LYAR
Immunogen:
A synthesized peptide derived from human LYAR(Accession Q9NX58), corresponding to amino acid residues K250-D300.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: CEP170
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CEP170
Gene Alias: 4933426L22Rik; A330004A13Rik; AI195353; centrosomal protein 170; centrosomal protein 170kDa; centrosomal protein of 170 kDa; CEP170; FAM68A; KAB; KARP-1-binding protein; KARP1-binding protein; KIAA0470; XRCC5 binding protein
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 545389, 9859
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q5SW79, Q6A065
Gene Symbols: CEP170
Immunogen: A synthesized peptide derived from human CEP170(Accession Q5SW79), corresponding to amino acid residues V705-E755.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CEP170
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CEP170
Gene Alias:
4933426L22Rik; A330004A13Rik; AI195353; centrosomal protein 170; centrosomal protein 170kDa; centrosomal protein of 170 kDa; CEP170; FAM68A; KAB; KARP-1-binding protein; KARP1-binding protein; KIAA0470; XRCC5 binding protein
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
545389, 9859
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q5SW79, Q6A065
Gene Symbols:
CEP170
Immunogen:
A synthesized peptide derived from human CEP170(Accession Q5SW79), corresponding to amino acid residues V705-E755.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: CEP55
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CEP55
Gene Alias: 1200008O12Rik; 2700032M20Rik; C10orf3; cancer/testis antigen 111; centrosomal protein 55; centrosomal protein 55kDa; centrosomal protein of 55 kDa; centrosomal protein of 55 kDa; LOW QUALITY PROTEIN: centrosomal protein of 55 kDa; centrosomal protein of 55 kDa-like protein; CEP55; CT111; RGD1305340; Up-regulated in colon cancer 6; URCC6
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55165
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q53EZ4
Gene Symbols: CEP55
Immunogen: A synthesized peptide derived from human CEP55(Accession Q53EZ4), corresponding to amino acid residues Q399-A449.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CEP55
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CEP55
Gene Alias:
1200008O12Rik; 2700032M20Rik; C10orf3; cancer/testis antigen 111; centrosomal protein 55; centrosomal protein 55kDa; centrosomal protein of 55 kDa; centrosomal protein of 55 kDa; LOW QUALITY PROTEIN: centrosomal protein of 55 kDa; centrosomal protein of 55 kDa-like protein; CEP55; CT111; RGD1305340; Up-regulated in colon cancer 6; URCC6
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55165
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q53EZ4
Gene Symbols:
CEP55
Immunogen:
A synthesized peptide derived from human CEP55(Accession Q53EZ4), corresponding to amino acid residues Q399-A449.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: BITE
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CEP70
Gene Alias: 6720484E09Rik; BITE; C030018L16Rik; centrosomal protein 70; centrosomal protein 70kDa; Centrosomal protein of 70 kDa; CEP70; I79_009119; p10-binding protein; testicular tissue protein Li 36
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 367153, 80321
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q5PQQ9, Q8NHQ1
Gene Symbols: CEP70
Immunogen: A synthesized peptide derived from human CEP70(Accession Q8NHQ1), corresponding to amino acid residues E243-Q293.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
BITE
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CEP70
Gene Alias:
6720484E09Rik; BITE; C030018L16Rik; centrosomal protein 70; centrosomal protein 70kDa; Centrosomal protein of 70 kDa; CEP70; I79_009119; p10-binding protein; testicular tissue protein Li 36
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
367153, 80321
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q5PQQ9, Q8NHQ1
Gene Symbols:
CEP70
Immunogen:
A synthesized peptide derived from human CEP70(Accession Q8NHQ1), corresponding to amino acid residues E243-Q293.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG