PIPA5101600

IFI16 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5101600-Each-of-1 In Stock ₹ 44,705.10

PIPA5101600 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

IFI16

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IFI16

Gene Alias

gamma-interferon-inducible protein 16; IFI 16C; IFI16; Ifi-16; IFNGIP1; interferon gamma inducible protein 16; interferon, gamma-inducible protein 16; interferon-gamma induced protein IFI 16; interferon-inducible myeloid differentiation transcriptional activator; PYHIN2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3428

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q16666

Gene Symbols

IFI16

Immunogen

A synthesized peptide derived from human IFI16(Accession Q16666), corresponding to amino acid residues E739-F785.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5102546

--

Img

Thermo Scientific

PIPA5103420

--

Img

Novus Biologicals

NB520968

--

Img

Thermo Scientific

PIMA527502

--

Img

Thermo Scientific

PIPA5102991

--

Img

Novus Biologicals

NB099222

--

Img

Novus Biologicals

NB088033

--

Img

Novus Biologicals

NB325370

--

Description

  • Antibody detects endogenous levels of total IFI16
  • IFI16 (gamma-inteferon-inducible protein 16) binds double-stranded DNA
  • It binds preferentially to supercoiled DNA and cruciform DNA structures
  • It seems to be involved in transcriptional regulation and as a transcriptional repressor
  • IFI16 may have a role in the regulation of hematopoietic differentiation through activation of unknown target genes
  • It controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein
  • IFI16 is also involved in innate immune response by recognizing viral dsDNA in the cytosol and nucleus
  • After binding to viral DNA in the cytoplasm, IFI16 recruits TMEM173/STING and mediates the induction of IFN-beta
  • It is necessary to activate the IFR3 signaling cascade suring human herpes simplex virus 1 infection and promotes the assembly of heterochromatin on herpesviral DNA and inhibiton of viral immediate-early gene expression and replication
  • IFI16 is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5101600

--


Antigen:
IFI16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFI16

Gene Alias:
gamma-interferon-inducible protein 16; IFI 16C; IFI16; Ifi-16; IFNGIP1; interferon gamma inducible protein 16; interferon, gamma-inducible protein 16; interferon-gamma induced protein IFI 16; interferon-inducible myeloid differentiation transcriptional activator; PYHIN2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3428

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q16666

Gene Symbols:
IFI16

Immunogen:
A synthesized peptide derived from human IFI16(Accession Q16666), corresponding to amino acid residues E739-F785.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101604

--


Antigen:
Connexin 25

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GJB7

Gene Alias:
bA136M9.1; connexin 25; connexin25; connexin-25; CX25; Gap junction beta-7 protein; gap junction protein beta 7; gap junction protein, beta 7, 25kDa; GJB7

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
375519

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6PEY0

Gene Symbols:
GJB7

Immunogen:
A synthesized peptide derived from human GJB7(Accession Q6PEY0), corresponding to amino acid residues I178-V223.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101605

--


Antigen:
C2orf3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GCFC2

Gene Alias:
A130099G21; AW146020; C2orf3; DNABF; GC binding factor; GC bindng factor; GCF; GCF2; GCFC2; GC-rich sequence DNA binding factor 2; GC-rich sequence DNA-binding factor; GC-rich sequence DNA-binding factor 2; RGD1304792; TCF9; TCF-9; Transcription factor 9; transcription factor 9 (binds GC-rich sequences)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
330361, 6936

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P16383, Q8BKT3

Gene Symbols:
GCFC2

Immunogen:
A synthesized peptide derived from human GCFC2(Accession P16383), corresponding to amino acid residues L514-D564.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101606

--


Antigen:
POFUT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POFUT1

Gene Alias:
DDD2; FUT12; GDP-fucose protein O-fucosyltransferase 1; KIAA0180; mKIAA0180; o-fucosyltransferase protein; O-Fuc-T; OFUCT1; O-FucT-1; O-FucT-1a; O-FucT-1b; O-FUT; peptide-O-fucosyltransferase 1; Pofut1; pofut1 {ECO:0000312; protein O-fucosyltransferase 1; protein O-fucosyltransferase 1 isoform 1 precursor; protein O-fucosyltransferase 1a; protein O-fucosyltransferase 1b; protein-O-fucosyltransferase 1; RGD:1303001}; zgc:110472

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140484, 23509, 311551

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6EV70, Q91ZW2, Q9H488

Gene Symbols:
POFUT1

Immunogen:
A synthesized peptide derived from human POFUT1(Accession Q9H488), corresponding to amino acid residues Q338-F388.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG