PIPA5101657
CD206 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101657-Each-of-1 | In Stock | ₹ 44,191.74 |
PIPA5101657 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,191.74
GST (18%): ₹ 7,954.513
Total Price: ₹ 52,146.253
Antigen
CD206
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Mrc1
Gene Alias
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17533, 291327, 4360
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P22897, Q61830
Gene Symbols
Mrc1
Immunogen
A synthesized peptide derived from human MRC1(Accession P22897), corresponding to amino acid residues P642-N692.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Antibody detects endogenous levels of total MRC1
- CD206 (MSR, Mannose receptor, MRC1) is a 175 kDa transmembrane protein belonging to the group of pattern recognition receptors
- CD206 is predominantly expressed in tissue macrophages, dendritic cells, a subpopulation of endothelial cells and sperm cells
- CD206 is thought to play a role in the innate and adaptive immune response
- CD206 is also expressed on microglia and mato cells of the brain but not astrocytes or neurons
- CD206 also mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta)
- While the normal role of CD206 is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Amyloid beta deposition in Alzheimer's disease (AD)
- CD206’s gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing
- The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs)
- The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms
- CD206 has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis
- The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages
- Other diseases associated with CD206 dysfunction include leprosy and Gaucher’s Disease.
Compare Similar Items
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Antigen: CD206
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mrc1
Gene Alias: AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17533, 291327, 4360
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P22897, Q61830
Gene Symbols: Mrc1
Immunogen: A synthesized peptide derived from human MRC1(Accession P22897), corresponding to amino acid residues P642-N692.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CD206
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mrc1
Gene Alias:
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17533, 291327, 4360
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P22897, Q61830
Gene Symbols:
Mrc1
Immunogen:
A synthesized peptide derived from human MRC1(Accession P22897), corresponding to amino acid residues P642-N692.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MASP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MASP2
Gene Alias: mannan binding lectin serine peptidase 2; mannan-binding; mannan-binding lectin serine peptidase 1 pseudogene 1; mannan-binding lectin serine peptidase 2; mannan-binding lectin serine peptidase 2 variant 1; mannan-binding lectin serine peptidase 2 variant 2; mannan-binding lectin serine peptidase 2 variant 3; mannan-binding lectin serine peptidase 2 variant 4; mannan-binding lectin serine protease 1 pseudogene 1; mannan-binding lectin serine protease 2; Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain; mannose binding lectin-associated serine protease-2; mannose-binding protein-associated serine protease 2; MAp19; MASP1P1; Masp2; MASP-2; MBL-associated plasma protein of 19 kD; MBL-associated serine protease 2; sb:eu714; small MBL-associated protein; sMAP; wu:fb62a09
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10747, 17175
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O00187, Q91WP0
Gene Symbols: MASP2
Immunogen: A synthesized peptide derived from human MASP2(Accession O00187), corresponding to amino acid residues D226-I276.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MASP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MASP2
Gene Alias:
mannan binding lectin serine peptidase 2; mannan-binding; mannan-binding lectin serine peptidase 1 pseudogene 1; mannan-binding lectin serine peptidase 2; mannan-binding lectin serine peptidase 2 variant 1; mannan-binding lectin serine peptidase 2 variant 2; mannan-binding lectin serine peptidase 2 variant 3; mannan-binding lectin serine peptidase 2 variant 4; mannan-binding lectin serine protease 1 pseudogene 1; mannan-binding lectin serine protease 2; Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain; mannose binding lectin-associated serine protease-2; mannose-binding protein-associated serine protease 2; MAp19; MASP1P1; Masp2; MASP-2; MBL-associated plasma protein of 19 kD; MBL-associated serine protease 2; sb:eu714; small MBL-associated protein; sMAP; wu:fb62a09
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10747, 17175
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O00187, Q91WP0
Gene Symbols:
MASP2
Immunogen:
A synthesized peptide derived from human MASP2(Accession O00187), corresponding to amino acid residues D226-I276.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: CTAGE5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mia2
Gene Alias: cTAGE family member 5; CTAGE family member 5 ER export factor; CTAGE family member 5, ER export factor; CTAGE family, member 5; CTAGE5; cutaneous T-cell lymphoma-associated antigen 5; LOW QUALITY PROTEIN: melanoma inhibitory activity protein 2; MEA11; MEA6; melanoma inhibitory activity 2; melanoma inhibitory activity protein 2; meningioma expressed antigen 6 (coiled-coil proline-rich); meningioma-expressed antigen 6/11; MGEA; MGEA11; MGEA6; MIA SH3 domain ER export factor 2; MIA2; protein cTAGE-5
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4253
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q96PC5
Gene Symbols: Mia2
Immunogen: A synthesized peptide derived from human MIA2, corresponding to a region within C-terminal amino acids.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CTAGE5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mia2
Gene Alias:
cTAGE family member 5; CTAGE family member 5 ER export factor; CTAGE family member 5, ER export factor; CTAGE family, member 5; CTAGE5; cutaneous T-cell lymphoma-associated antigen 5; LOW QUALITY PROTEIN: melanoma inhibitory activity protein 2; MEA11; MEA6; melanoma inhibitory activity 2; melanoma inhibitory activity protein 2; meningioma expressed antigen 6 (coiled-coil proline-rich); meningioma-expressed antigen 6/11; MGEA; MGEA11; MGEA6; MIA SH3 domain ER export factor 2; MIA2; protein cTAGE-5
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4253
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q96PC5
Gene Symbols:
Mia2
Immunogen:
A synthesized peptide derived from human MIA2, corresponding to a region within C-terminal amino acids.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PGRMC2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pgrmc2
Gene Alias: 4631434O19Rik; 5730409G06Rik; DG6; Membrane-associated progesterone receptor component 2; Pgrmc2; PMBP; progesterone membrane binding protein; Progesterone membrane-binding protein; progesterone receptor membrane component 2; steroid receptor protein DG6
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10424, 361940, 70804
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O15173, Q5XIU9, Q80UU9
Gene Symbols: Pgrmc2
Immunogen: A synthesized peptide derived from human PGRMC2(Accession O15173), corresponding to amino acid residues F190-D223.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PGRMC2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pgrmc2
Gene Alias:
4631434O19Rik; 5730409G06Rik; DG6; Membrane-associated progesterone receptor component 2; Pgrmc2; PMBP; progesterone membrane binding protein; Progesterone membrane-binding protein; progesterone receptor membrane component 2; steroid receptor protein DG6
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10424, 361940, 70804
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O15173, Q5XIU9, Q80UU9
Gene Symbols:
Pgrmc2
Immunogen:
A synthesized peptide derived from human PGRMC2(Accession O15173), corresponding to amino acid residues F190-D223.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG