PIPA5101846

ARHGEF11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5101846-Each-of-1 In Stock ₹ 44,705.10

PIPA5101846 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ARHGEF11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ARHGEF11

Gene Alias

Arhgef11; B930073M02; E130307F09; glutamate transporter EAAT4 associated protein 48; glutamate transporter EAAT4-associated protein 48; Gtrap48; KIAA0380; mKIAA0380; PDZ-RhoGEF; Prg; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; rho guanine nucleotide exchange factor 11; RhoA-specific guanine nucleotide exchange factor; RhoGEF; RhoGEF glutamate transport modulator; RhoGEF glutamate transport modulator GTRAP48; RP11-356J7.2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

213498, 78966, 9826

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O15085, Q9ES67

Gene Symbols

ARHGEF11

Immunogen

A synthesized peptide derived from human ARHGEF11(Accession O15085), corresponding to amino acid residues L1432-P1482.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total ARHGEF11
  • ARHGEF11 is a 1527 amino acid protein with tandem dbl homology and pleckstrin homology domains, PDZ domain, two proline rich sequences and a regulatory G protein-signaling (RGS) sequence
  • It acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase, but not for RAC1 or CDC42 and acts as GTPase-activating protein (GAP) for GNA12 and GNA13
  • It forms a complex with G proteins and stimulates neurite through retraction Rho-dependent signals
  • ARHGEF11 increases glutamate transport 4-fold
  • It interacts with EAAT4 and modulates its uptake activity and perisynaptic distribution at glutamatergic synapses
  • It is known to induce the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia
  • It is ubiquitously expressed, in brain, lung, liver, kidney and skeletal muscle.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5101846

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Antigen:
ARHGEF11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARHGEF11

Gene Alias:
Arhgef11; B930073M02; E130307F09; glutamate transporter EAAT4 associated protein 48; glutamate transporter EAAT4-associated protein 48; Gtrap48; KIAA0380; mKIAA0380; PDZ-RhoGEF; Prg; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; rho guanine nucleotide exchange factor 11; RhoA-specific guanine nucleotide exchange factor; RhoGEF; RhoGEF glutamate transport modulator; RhoGEF glutamate transport modulator GTRAP48; RP11-356J7.2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
213498, 78966, 9826

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O15085, Q9ES67

Gene Symbols:
ARHGEF11

Immunogen:
A synthesized peptide derived from human ARHGEF11(Accession O15085), corresponding to amino acid residues L1432-P1482.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101848

--


Antigen:
ARHGEF3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARHGEF3

Gene Alias:
1200004I24Rik; 59.8 kDA protein; 9830169H03Rik; ARHG3; ARHGEF3; C76747; DKFZP434F2429; Exchange factor found in platelets and leukemic and neuronal tissues; exchange factor found in platelets and leukemic and neuronal tissues, XPLN; GEF3; MGC118905; Rho guanine nucleotide exchange factor (GEF) 3; Rho guanine nucleotide exchange factor 3; RhoGEF protein; STA3; Xpln

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
290541, 50650, 71704

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q91X46, Q9NR81

Gene Symbols:
ARHGEF3

Immunogen:
A synthesized peptide derived from human ARHGEF3(Accession Q9NR81), corresponding to amino acid residues F467-G517.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101851

--


Antigen:
RPL7L1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPL7L1

Gene Alias:
1500016H10Rik; 60S ribosomal protein L7-like 1; dJ475N16.4; Large ribosomal subunit protein uL30-like 1; RGD1308469; ribosomal protein L7 like 1; ribosomal protein L7-like 1; RPL7L1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
285855

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6DKI1

Gene Symbols:
RPL7L1

Immunogen:
A synthesized peptide derived from human RPL7L1(Accession Q6DKI1), corresponding to amino acid residues V172-V222.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101852

--


Antigen:
RIMKLA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RIMKLA

Gene Alias:
B930030J24; Fam80a; family with sequence similarity 80, member A; NAAG synthetase A; NAAGS; NAAGS-II; N-acetylaspartylglutamate synthase A; N-acetylaspartyl-glutamate synthetase A; N-acetylaspartylglutamate synthetase II; N-acetylaspartylglutamylglutamate synthase A; ribosomal modification protein rimK like family member A; ribosomal modification protein rimK-like family member A; ribosomal protein S6 modification-like protein A; Rimk; Rimkla; RP11-157D18.1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
194237, 284716

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6PFX8, Q8IXN7

Gene Symbols:
RIMKLA

Immunogen:
A synthesized peptide derived from human RIMKLA(Accession Q8IXN7), corresponding to amino acid residues K111-G161.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG