PIPA5101853
RFWD3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101853-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5101853 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
RFWD3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RFWD3
Gene Alias
BC027246; E3 ubiquitin-protein ligase RFWD3; Rfwd3; RGD1305243; ring finger and WD repeat domain 3; RING finger and WD repeat domain-containing protein 3; RING finger protein 201; Rnf201
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55159
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q6PCD5
Gene Symbols
RFWD3
Immunogen
A synthesized peptide derived from human RFWD3(Accession Q6PCD5), corresponding to amino acid residues S119-T169.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Antibody detects endogenous levels of total RFWD3
- E3 ubiquitin-protein ligase required for the repair of DNA interstrand cross-links (ICL) in response to DNA damage (PubMed:21504906, PubMed:21558276, PubMed:26474068, PubMed:28575657, PubMed:28575658)
- Plays a key role in RPA-mediated DNA damage signaling and repair (PubMed:21504906, PubMed:21558276, PubMed:26474068, PubMed:28575657, PubMed:28575658, PubMed:28691929)
- Acts by mediating ubiquitination of the RPA complex (RPA1, RPA2 and RPA3 subunits) and RAD51 at stalled replication forks, leading to remove them from DNA damage sites and promote homologous recombination (PubMed:26474068, PubMed:28575657, PubMed:28575658)
- Also mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint (PubMed:20173098)
- May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome (PubMed:20173098)
- In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53 (PubMed:20173098)
- [UniProt]
Compare Similar Items
Show Difference
Antigen: RFWD3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RFWD3
Gene Alias: BC027246; E3 ubiquitin-protein ligase RFWD3; Rfwd3; RGD1305243; ring finger and WD repeat domain 3; RING finger and WD repeat domain-containing protein 3; RING finger protein 201; Rnf201
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55159
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q6PCD5
Gene Symbols: RFWD3
Immunogen: A synthesized peptide derived from human RFWD3(Accession Q6PCD5), corresponding to amino acid residues S119-T169.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RFWD3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RFWD3
Gene Alias:
BC027246; E3 ubiquitin-protein ligase RFWD3; Rfwd3; RGD1305243; ring finger and WD repeat domain 3; RING finger and WD repeat domain-containing protein 3; RING finger protein 201; Rnf201
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55159
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q6PCD5
Gene Symbols:
RFWD3
Immunogen:
A synthesized peptide derived from human RFWD3(Accession Q6PCD5), corresponding to amino acid residues S119-T169.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: RCL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RCL1
Gene Alias: 2310040A02Rik; Ab1-353; Ac1292; AI789745; C76567; HSPC338; Rcl1; RNA 3'-terminal phosphate cyclase-like protein; RNA cyclase homolog; RNA terminal phosphate cyclase like 1; RNA terminal phosphate cyclase-like 1; Rnac; RPC2; RPCL1; RTC2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10171, 309301, 59028
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9JJT0, Q9Y2P8
Gene Symbols: RCL1
Immunogen: A synthesized peptide derived from human RCL1(Accession Q9Y2P8), corresponding to amino acid residues I325-K373.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RCL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RCL1
Gene Alias:
2310040A02Rik; Ab1-353; Ac1292; AI789745; C76567; HSPC338; Rcl1; RNA 3'-terminal phosphate cyclase-like protein; RNA cyclase homolog; RNA terminal phosphate cyclase like 1; RNA terminal phosphate cyclase-like 1; Rnac; RPC2; RPCL1; RTC2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10171, 309301, 59028
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9JJT0, Q9Y2P8
Gene Symbols:
RCL1
Immunogen:
A synthesized peptide derived from human RCL1(Accession Q9Y2P8), corresponding to amino acid residues I325-K373.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RPAP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rpap2
Gene Alias: AW060207; C1orf82; Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2; RNA polymerase II associated protein 2; RNA polymerase II-associated protein 2; RPAP2; Rtr1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 231571, 79871
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q8IXW5, Q8VC34
Gene Symbols: Rpap2
Immunogen: A synthesized peptide derived from human RPAP2(Accession Q8IXW5), corresponding to amino acid residues S418-R468.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
RPAP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rpap2
Gene Alias:
AW060207; C1orf82; Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2; RNA polymerase II associated protein 2; RNA polymerase II-associated protein 2; RPAP2; Rtr1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
231571, 79871
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q8IXW5, Q8VC34
Gene Symbols:
Rpap2
Immunogen:
A synthesized peptide derived from human RPAP2(Accession Q8IXW5), corresponding to amino acid residues S418-R468.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: RUFY1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RUFY1
Gene Alias: 3000002E04Rik; FYVE-finger containing protein; FYVE-finger protein EIP1; La-binding protein 1; Rab4a interacting protein; rab4-interacting protein; Rabip4; RUFY1; RUN and FYVE domain containing 1; RUN and FYVE domain-containing protein 1; ZFYVE12; zinc finger FYVE domain-containing protein 12
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 216724, 80230
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q8BIJ7, Q96T51
Gene Symbols: RUFY1
Immunogen: A synthesized peptide derived from human RUFY1(Accession Q96T51), corresponding to amino acid residues V459-E509.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
RUFY1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RUFY1
Gene Alias:
3000002E04Rik; FYVE-finger containing protein; FYVE-finger protein EIP1; La-binding protein 1; Rab4a interacting protein; rab4-interacting protein; Rabip4; RUFY1; RUN and FYVE domain containing 1; RUN and FYVE domain-containing protein 1; ZFYVE12; zinc finger FYVE domain-containing protein 12
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
216724, 80230
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q8BIJ7, Q96T51
Gene Symbols:
RUFY1
Immunogen:
A synthesized peptide derived from human RUFY1(Accession Q96T51), corresponding to amino acid residues V459-E509.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG