PIPA5102027
MERTK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5102027-Each-of-1 | In Stock | ₹ 43,592.82 |
PIPA5102027 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,592.82
GST (18%): ₹ 7,846.708
Total Price: ₹ 51,439.528
Antigen
MERTK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Mertk
Gene Alias
c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10461, 17289, 65037
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P57097, Q12866, Q60805
Gene Symbols
Mertk
Immunogen
A synthesized peptide derived from human MERTK(Accession Q12866), corresponding to amino acid residues R727-Y777.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total MERTK
- MERTK (cMER) is a tyrosine kinase proto-oncogene and is involved in the retinal pigment epithelium (RPE) phagocytosis pathway, which is implicated in human retinal disease
- Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis)
- Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules
- Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1
- MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment
- Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis
- Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
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Antigen: MERTK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mertk
Gene Alias: c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10461, 17289, 65037
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P57097, Q12866, Q60805
Gene Symbols: Mertk
Immunogen: A synthesized peptide derived from human MERTK(Accession Q12866), corresponding to amino acid residues R727-Y777.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MERTK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mertk
Gene Alias:
c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10461, 17289, 65037
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P57097, Q12866, Q60805
Gene Symbols:
Mertk
Immunogen:
A synthesized peptide derived from human MERTK(Accession Q12866), corresponding to amino acid residues R727-Y777.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PHKG1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PHKG1
Gene Alias: gamma phosphorylase kinase; MGC137450 protein; PHGK; PHKG; PHKG1; PHKgammaM; PHK-gammaM; PHK-gamma-M; PHKgamma-M; PHKIN01; phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform; Phosphorylase B kinase gamma catalytic chain, skeletal muscle isoform (Phosphorylase kinase gamma subunit 1); phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; phosphorylase kinase; phosphorylase kinase catalytic subunit gamma 1; phosphorylase kinase gamma; phosphorylase kinase gamma 1; phosphorylase kinase gamma subunit; phosphorylase kinase gamma subunit 1; phosphorylase kinase subunit gamma 1; phosphorylase kinase subunit gamma-1; phosphorylase kinase, gamma 1; phosphorylase kinase, gamma 1 (muscle); serine/threonine-protein kinase PHKG1; unnamed protein product
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5260
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q16816
Gene Symbols: PHKG1
Immunogen: A synthesized peptide derived from human PHKG1(Accession Q16816), corresponding to amino acid residues G250-S300.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PHKG1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PHKG1
Gene Alias:
gamma phosphorylase kinase; MGC137450 protein; PHGK; PHKG; PHKG1; PHKgammaM; PHK-gammaM; PHK-gamma-M; PHKgamma-M; PHKIN01; phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform; Phosphorylase B kinase gamma catalytic chain, skeletal muscle isoform (Phosphorylase kinase gamma subunit 1); phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; phosphorylase kinase; phosphorylase kinase catalytic subunit gamma 1; phosphorylase kinase gamma; phosphorylase kinase gamma 1; phosphorylase kinase gamma subunit; phosphorylase kinase gamma subunit 1; phosphorylase kinase subunit gamma 1; phosphorylase kinase subunit gamma-1; phosphorylase kinase, gamma 1; phosphorylase kinase, gamma 1 (muscle); serine/threonine-protein kinase PHKG1; unnamed protein product
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5260
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q16816
Gene Symbols:
PHKG1
Immunogen:
A synthesized peptide derived from human PHKG1(Accession Q16816), corresponding to amino acid residues G250-S300.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ACTBL2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ACTBL2
Gene Alias: 4732495G21Rik; ACT; Actbl2; actin, beta like 2; actin, beta-like 2; actin-like protein; beta-actin-like protein 2; Kappa-actin
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 238880, 345651
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q562R1, Q8BFZ3
Gene Symbols: ACTBL2
Immunogen: A synthesized peptide derived from human ACTBL2(Accession Q562R1), corresponding to amino acid residues H89-A139.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ACTBL2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ACTBL2
Gene Alias:
4732495G21Rik; ACT; Actbl2; actin, beta like 2; actin, beta-like 2; actin-like protein; beta-actin-like protein 2; Kappa-actin
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
238880, 345651
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q562R1, Q8BFZ3
Gene Symbols:
ACTBL2
Immunogen:
A synthesized peptide derived from human ACTBL2(Accession Q562R1), corresponding to amino acid residues H89-A139.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: ERI1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ERI1
Gene Alias: 3 ' exoribonuclease; 3' exoribonuclease; 3110010F15Rik; 3'-5' exonuclease ERI1; 3'-5' exoribonuclease 1; 3'EXO; 3'HEXO; enhanced RNAi protein 1; enhanced RNAi three prime mRNA exonuclease homolog 1; ERI1; eri-1; Eri-1 homolog; exoribonuclease 1; HEXO; histone mRNA 3' end-specific exonuclease; histone mRNA 3'-end-specific exoribonuclease; Histone mRNA 3'-exonuclease 1; protei; protein 3'hExo; RGD1308378; Thex1; three prime histone mRNA exonuclease 1; three prime mRNA exonuclease 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 361159, 67276, 90459
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q5FVR4, Q7TMF2, Q8IV48
Gene Symbols: ERI1
Immunogen: A synthesized peptide derived from human ERI1(Accession Q8IV48), corresponding to amino acid residues F267-R317.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ERI1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ERI1
Gene Alias:
3 ' exoribonuclease; 3' exoribonuclease; 3110010F15Rik; 3'-5' exonuclease ERI1; 3'-5' exoribonuclease 1; 3'EXO; 3'HEXO; enhanced RNAi protein 1; enhanced RNAi three prime mRNA exonuclease homolog 1; ERI1; eri-1; Eri-1 homolog; exoribonuclease 1; HEXO; histone mRNA 3' end-specific exonuclease; histone mRNA 3'-end-specific exoribonuclease; Histone mRNA 3'-exonuclease 1; protei; protein 3'hExo; RGD1308378; Thex1; three prime histone mRNA exonuclease 1; three prime mRNA exonuclease 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
361159, 67276, 90459
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q5FVR4, Q7TMF2, Q8IV48
Gene Symbols:
ERI1
Immunogen:
A synthesized peptide derived from human ERI1(Accession Q8IV48), corresponding to amino acid residues F267-R317.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG