PIPA5102303

Perforin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102303-Each-of-1 In Stock ₹ 44,705.10

PIPA5102303 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Perforin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PRF1

Gene Alias

Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; PRF1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18646, 50669, 5551

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P10820, P14222, P35763

Gene Symbols

PRF1

Immunogen

A synthesized peptide derived from human PRF1(Accession P14222), corresponding to amino acid residues T74-S124.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total PRF1
  • Perforin is one of the major cytolytic proteins of cytolytic granules
  • Perforin is a cytolytic mediator and is stored in and released by cytoplasmic granules
  • Moreover, perforin is involved in immune defense against tumors and virus infections as mediated by cytotoxic lymphocytes
  • Perforin is a 555 amino acid protein with a 21 amino acid signal peptide, and has a molecular weight of 70 to 75 kD
  • Perforin is a pore forming protein with a mechanism of transmembrane channel formation similar to C9, and homology between perforin and C9 have been demonstrated
  • Studies show that perforin is expressed only in killer cell lines and not in helper T lymphocytes or other tumor cells tested
  • Perforin is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis
  • Defects in the perforin gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood
  • Alternative splicing results in multiple transcript variants of perforin.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5102303

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Antigen:
Perforin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRF1

Gene Alias:
Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; PRF1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18646, 50669, 5551

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P10820, P14222, P35763

Gene Symbols:
PRF1

Immunogen:
A synthesized peptide derived from human PRF1(Accession P14222), corresponding to amino acid residues T74-S124.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102304

--


Antigen:
BVES

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BVES

Gene Alias:
blood vessel epicardial substance; bves; hBVES; LGMD2X; mBVES; MGC42413; POP 1; POP1; POPDC 1; Popdc1; popdc1 protein; popeye 1; popeye domain containing 1; popeye domain-containing 1; popeye domain-containing protein 1; Popeye protein 1; zgc:86887

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11149, 23828, 365603

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q3BCU4, Q8NE79, Q9ES83

Gene Symbols:
BVES

Immunogen:
A synthesized peptide derived from human BVES(Accession Q8NE79), corresponding to amino acid residues S174-N224.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102306

--


Antigen:
DOK4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DOK4

Gene Alias:
docking protein 4; Dok4; Downstream of tyrosine kinase 4; insulin receptor substrate 5; IRS5; IRS-5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114255, 361364, 55715

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8TEW6, Q99KE3

Gene Symbols:
DOK4

Immunogen:
A synthesized peptide derived from human DOK4(Accession Q8TEW6), corresponding to amino acid residues S18-V68.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102309

--


Antigen:
NUDT6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUDT6

Gene Alias:
antisense basic fibroblast growth factor; Antisense basic fibroblast growth factor B; anti-sense basic fibroblast growth factor B; ASFGF2; Asfgf2b; FGF2AS; FGF-AS; Gfg; GFG1; GFG-1; Nucleoside diphosphate-linked moiety X motif 6; nudix (nucleoside diphosphate linked moiety X)-type motif 6; nudix hydrolase 6; nudix motif 6; Nudt6; Protein GFG

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11162, 207120, 229228

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P53370, P70563, Q8CH40

Gene Symbols:
NUDT6

Immunogen:
A synthesized peptide derived from human NUDT6(Accession P53370), corresponding to amino acid residues V144-E194.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG