PIPA5102433

MYOC Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102433-Each-of-1 In Stock ₹ 43,592.82

PIPA5102433 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

MYOC

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MYOC

Gene Alias

AI957332; GLC1A; GPOA; JOAG; JOAG1; juvenile-onset open-angle glaucoma 1; mutated trabecular meshwork-induced glucocorticoid response protein; MYOC; Myocilin; Myocilin 20 kDa N-terminal fragment; Myocilin 35 kDa N-terminal fragment; Myocilin 55 kDa subunit; myocilin trabecular meshwork inducible glucocorticoid response; myocilin trabecular meshwork inducible glucocorticoid response protein; Myocilin, C-terminal fragment; Myocilin, N-terminal fragment; myocilin, trabecular meshwork inducible glucocorticoid response; TIGR; trabecular meshwork inducible glucocorticoid response protein; trabecular meshwork-induced glucocorticoid response protein

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17926, 4653, 81523

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O70624, Q99972, Q9R1J4

Gene Symbols

MYOC

Immunogen

A synthesized peptide derived from human MYOC(Accession Q99972), corresponding to amino acid residues R342-Y392.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total MYOC
  • Myocilin is an extracellular protein expressed in the eye, including the retina, trabecular meshwork and ciliary body
  • Myocilin can form homomultimers in vivo and can also associate with components of the ECM via interactions with the Hep II domain of FibroPVRL1
  • In addition, myocilin interacts with myosin regulatory light chain, a component of the myosin motor protein complex
  • This interaction implies a role for myocilin in the actomyosin system, linking myocilin to the functional status of the trabecular meshwork (TM), which is responsible for controlling the intraocular pressure (IOP)
  • Alterations in functions of the TM may lead to IOP elevation and development of glaucoma, a major cause of blindness
  • Myocilin is encoded by MYOC (also designated TIGR), a gene that maps to the GLC1A locus on chromosome 1q24
  • 3 and is susceptible to mutations
  • Mutations in the MYOC gene are specifically linked with primary open angle glaucoma (POAG), a blinding disease characterized by progressive loss of retinal ganglion cells.

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Thermo Scientific

PIPA5102433

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Antigen:
MYOC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYOC

Gene Alias:
AI957332; GLC1A; GPOA; JOAG; JOAG1; juvenile-onset open-angle glaucoma 1; mutated trabecular meshwork-induced glucocorticoid response protein; MYOC; Myocilin; Myocilin 20 kDa N-terminal fragment; Myocilin 35 kDa N-terminal fragment; Myocilin 55 kDa subunit; myocilin trabecular meshwork inducible glucocorticoid response; myocilin trabecular meshwork inducible glucocorticoid response protein; Myocilin, C-terminal fragment; Myocilin, N-terminal fragment; myocilin, trabecular meshwork inducible glucocorticoid response; TIGR; trabecular meshwork inducible glucocorticoid response protein; trabecular meshwork-induced glucocorticoid response protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17926, 4653, 81523

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O70624, Q99972, Q9R1J4

Gene Symbols:
MYOC

Immunogen:
A synthesized peptide derived from human MYOC(Accession Q99972), corresponding to amino acid residues R342-Y392.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102435

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Antigen:
SULT1A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SULT1A1

Gene Alias:
AI266890; aryl sulfotransferase; Aryl sulfotransferase 1; Aryl sulfotransferase cytosolic 1A phenol-preferring member 3; Aryl sulfotransferase cytosolic, 1A, phenol-preferring, member 3; aryl sulfotransferase IV; arylsulfotransferase ST1A4; ASTIV; CSPS; HAST1/HAST2; MGC131921; MGC5163; Minoxidil sulfotransferase; mSTp1; Mx-ST; OK/SW-cl.88; OTTHUMP00000162568; OTTHUMP00000162569; P PST; P PST 1; Phenol sulfotransferase; Phenol sulfotransferase 1; Phenol sulfotransferase 1a1; phenol/aryl sulfotransferase; phenol-sulfating phenol sulfotransferase 1; P-PST; P-PST 1; PST; PST-1; St1a1; ST1A3; ST1A4; Stm; STP; STP1; sulfokinase; Sulfotransferase 1A1; sulfotransferase family 1A member 1; sulfotransferase family 1A, phenol-preferring, member 1; sulfotransferase family, cytosolic, 1A, phenol preferring; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; sulfotransferase, phenol preferring 1; sulphotransferase family cytosolic 1A phenol-prefering member 1; SULT1A1; Sult1a3; The

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20887, 6817, 83783

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P17988, P50225, P52840

Gene Symbols:
SULT1A1

Immunogen:
A synthesized peptide derived from human SULT1A1(Accession P50225), corresponding to amino acid residues G65-P115.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5102438

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Antigen:
TAP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TAP2

Gene Alias:
ABC transporter, MHC 2; ABC18; ABCB3; AI462429; Antigen peptide transporter 2; APT2; ATP dependent transport protein family member; ATP-binding cassette sub-family B member 3; ATP-binding cassette, sub-family B (MDR/TAP), member 3; Cim; D6S217E; Ham2; Ham-2; Histocompatibility antigen modifier 2; jas; MTP2; Peptide supply factor 2; peptide transporter involved in antigen processing 2; Peptide transporter PSF2; Peptide transporter TAP2; PSF2; PSF-2; Really interesting new gene 11 protein; RING11; TAP2; Tap-2; Transporter 2 ABC (ATP binding cassette); transporter 2 ATP-binding cassette sub-family B; transporter 2, ABC (ATP binding cassette); transporter 2, ATP binding cassette subfamily B member; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP); Y1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21355, 24812, 6891

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P36371, P36372, Q03519

Gene Symbols:
TAP2

Immunogen:
A synthesized peptide derived from human TAP2(Accession Q03519), corresponding to amino acid residues E538-F588.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102439

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Antigen:
HLA-DRB3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-DRB3

Gene Alias:
DR7; DRB1; DRw10; HLA class II histocompatibility antigen, DR beta 3 chain; HLA class II histocompatibility antigen, DRB1-7 beta chain; HLA DR3B; HLA-DR1B; HLA-DR3B; HLA-DRB; HLA-DRB3; human leucocyte antigen DRB3; major histocompatibility complex, class II, DR beta 3; MGC117330; MHC Class II antigen; MHC class II antigen DR beta 3 chain; MHC class II antigen DRB3; MHC class II HLA-DR beta 3 chain; SS1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3125

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P79483

Gene Symbols:
HLA-DRB3

Immunogen:
A synthesized peptide derived from human HLA-DRB3(Accession P79483), corresponding to amino acid residues A78-V128.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG