PIPA5102780
MTH1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5102780-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5102780 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MTH1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NUDT1
Gene Alias
2-hydroxy-dATP diphosphatase; 7,8-dihydro-8-oxoguanine triphosphatase; 8-oxo-7,8-dihydro-2'-dGTPase; 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase; 8-oxo-7,8-dihydroguanosine triphosphatase; 8-oxo-dGTPase; Mth1; mutT human homolog (8-oxo-dGTPase); mutT human homolog 1; nucleoside diphosphate-linked moiety X motif 1; nucleoside diphosphate-linked moiety X-type motif 1; nudix (nucleoside diphosphate linked moiety X)-type motif 1; nudix hydrolase 1; nudix motif 1; nudix-type motif 1; NUDT1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
117260, 17766, 4521
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P36639, P53368, P53369
Gene Symbols
NUDT1
Immunogen
A synthesized peptide derived from human NUDT1(Accession P36639), corresponding to amino acid residues G62-G83.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total NUDT1
- Oxygen radicals damage chromosomal DNA causing cell death and inducing mutations
- Among the various classes of DNA damage caused by oxygen radicals, an oxidized form of guanine base (8-oxoguanine) appears to be important as it can pair with cytosine and adenine and G:C to T:A transversion mutation occurs
- A significant amount of 8-OxoG is formed in the chromosomal DNA of mammalian cells, with most damaged nucleotides excised from the DNA and excreted in the urine
- Along with 8-oxoG being present in oxidatively damaged DNA, 8-oxo-deoxyguanosine (8-oxo-dGTP) is formed in the nucleotide pool during normal cellular metabolism and following oxidative stress
- The 8-oxo-dGTP nucleotide can be incorporated in DNA during polymerization and can result in a mispairing unless repaired
- MTH converts 8-oxo-dGTP in the nucleotide pool to the monophosphate and prevents the misincorporation of 8-oxo-dGTP into DNA (Figure courtesy of Dr
- Mark Kelley)
- MTH also recognizes 8-oxo-rGTP, which could incorporate into RNA during gene transcription leading to missense or nonsense protein production.
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Antigen: MTH1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NUDT1
Gene Alias: 2-hydroxy-dATP diphosphatase; 7,8-dihydro-8-oxoguanine triphosphatase; 8-oxo-7,8-dihydro-2'-dGTPase; 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase; 8-oxo-7,8-dihydroguanosine triphosphatase; 8-oxo-dGTPase; Mth1; mutT human homolog (8-oxo-dGTPase); mutT human homolog 1; nucleoside diphosphate-linked moiety X motif 1; nucleoside diphosphate-linked moiety X-type motif 1; nudix (nucleoside diphosphate linked moiety X)-type motif 1; nudix hydrolase 1; nudix motif 1; nudix-type motif 1; NUDT1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 117260, 17766, 4521
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P36639, P53368, P53369
Gene Symbols: NUDT1
Immunogen: A synthesized peptide derived from human NUDT1(Accession P36639), corresponding to amino acid residues G62-G83.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MTH1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NUDT1
Gene Alias:
2-hydroxy-dATP diphosphatase; 7,8-dihydro-8-oxoguanine triphosphatase; 8-oxo-7,8-dihydro-2'-dGTPase; 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase; 8-oxo-7,8-dihydroguanosine triphosphatase; 8-oxo-dGTPase; Mth1; mutT human homolog (8-oxo-dGTPase); mutT human homolog 1; nucleoside diphosphate-linked moiety X motif 1; nucleoside diphosphate-linked moiety X-type motif 1; nudix (nucleoside diphosphate linked moiety X)-type motif 1; nudix hydrolase 1; nudix motif 1; nudix-type motif 1; NUDT1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
117260, 17766, 4521
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P36639, P53368, P53369
Gene Symbols:
NUDT1
Immunogen:
A synthesized peptide derived from human NUDT1(Accession P36639), corresponding to amino acid residues G62-G83.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PFKM
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PFKM
Gene Alias: 6-phosphofructo-1-kinase; 6-phosphofructokinase type A; 6-phosphofructokinase, muscle type; AI131669; ATP-dependent 6-phosphofructokinase, muscle type; ATP-dependent 6-phosphofructokinase, muscle type {ECO:0000255; ATP-PFK; ATP-PFK {ECO:0000255; GSD7; HAMAP-Rule:MF_03184}; PFK; PFK1; PFK-1; Pfk4; Pfk-4; Pfka; PFK-A; PFKM; Pfk-m; PFKX; Phosphofructo-1-kinase isozyme A; phosphofructokinase 1; phosphofructokinase 4; phosphofructokinase M variant 3/4; phosphofructokinase muscle; phosphofructokinase, muscle; phosphofructokinase, polypeptide X; phosphofructokinase-1 A isozyme; phosphofructokinase-A; phosphofructokinase-M; phosphofructokinase-M (connecting peptide); phosphohexokinase; phosphohexokinase {ECO:0000255; PPP1R122; protein phosphatase 1, regulatory subunit 122
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18642, 5213, 65152
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P08237, P47857, P47858
Gene Symbols: PFKM
Immunogen: A synthesized peptide derived from human PFKM(Accession P08237), corresponding to amino acid residues F49-L99.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PFKM
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PFKM
Gene Alias:
6-phosphofructo-1-kinase; 6-phosphofructokinase type A; 6-phosphofructokinase, muscle type; AI131669; ATP-dependent 6-phosphofructokinase, muscle type; ATP-dependent 6-phosphofructokinase, muscle type {ECO:0000255; ATP-PFK; ATP-PFK {ECO:0000255; GSD7; HAMAP-Rule:MF_03184}; PFK; PFK1; PFK-1; Pfk4; Pfk-4; Pfka; PFK-A; PFKM; Pfk-m; PFKX; Phosphofructo-1-kinase isozyme A; phosphofructokinase 1; phosphofructokinase 4; phosphofructokinase M variant 3/4; phosphofructokinase muscle; phosphofructokinase, muscle; phosphofructokinase, polypeptide X; phosphofructokinase-1 A isozyme; phosphofructokinase-A; phosphofructokinase-M; phosphofructokinase-M (connecting peptide); phosphohexokinase; phosphohexokinase {ECO:0000255; PPP1R122; protein phosphatase 1, regulatory subunit 122
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18642, 5213, 65152
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P08237, P47857, P47858
Gene Symbols:
PFKM
Immunogen:
A synthesized peptide derived from human PFKM(Accession P08237), corresponding to amino acid residues F49-L99.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PRPF3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PRPF3
Gene Alias: 3632413F13Rik; HPRP3; HPRP3P; MGC137653 protein; pre-mRNA processing factor 3; pre-mRNA-splicing factor 3; PRP3; PRP3 pre-mRNA processing factor 3 homolog; PRP3 pre-mRNA processing factor 3 homolog (yeast); Prp3p; PRPF3; RP18; SNRNP90; U4/U6 small nuclear ribonucleoprotein Prp3; U4/U6 snRNP 90 kDa protein; U4/U6-associated RNA splicing factor
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 361995, 70767, 9129
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O43395, Q922U1
Gene Symbols: PRPF3
Immunogen: A synthesized peptide derived from human PRPF3(Accession O43395), corresponding to amino acid residues P53-K103.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PRPF3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PRPF3
Gene Alias:
3632413F13Rik; HPRP3; HPRP3P; MGC137653 protein; pre-mRNA processing factor 3; pre-mRNA-splicing factor 3; PRP3; PRP3 pre-mRNA processing factor 3 homolog; PRP3 pre-mRNA processing factor 3 homolog (yeast); Prp3p; PRPF3; RP18; SNRNP90; U4/U6 small nuclear ribonucleoprotein Prp3; U4/U6 snRNP 90 kDa protein; U4/U6-associated RNA splicing factor
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
361995, 70767, 9129
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O43395, Q922U1
Gene Symbols:
PRPF3
Immunogen:
A synthesized peptide derived from human PRPF3(Accession O43395), corresponding to amino acid residues P53-K103.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PSMB2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PSMB2
Gene Alias: AU045357; AW108089; C7-I; D4Wsu33e; HC7-I; Macropain subunit C7-I; multicatalytic endopeptidase complex subunit C7-1; multicatalytic endopeptidase complex subunit C7-I; proteasome (prosome, macropain) subunit, beta type 2; proteasome (prosome, macropain) subunit, beta type, 2; proteasome beta 2 subunit; proteasome component C7-I; proteasome subunit beta 2; proteasome subunit beta type-2; proteasome subunit, beta type, 2; PSMB2; testicular tissue protein Li 152
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26445, 29675, 5690
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P40307, P49721, Q9R1P3
Gene Symbols: PSMB2
Immunogen: A synthesized peptide derived from human PSMB2(Accession P49721), corresponding to amino acid residues E49-H99.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PSMB2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PSMB2
Gene Alias:
AU045357; AW108089; C7-I; D4Wsu33e; HC7-I; Macropain subunit C7-I; multicatalytic endopeptidase complex subunit C7-1; multicatalytic endopeptidase complex subunit C7-I; proteasome (prosome, macropain) subunit, beta type 2; proteasome (prosome, macropain) subunit, beta type, 2; proteasome beta 2 subunit; proteasome component C7-I; proteasome subunit beta 2; proteasome subunit beta type-2; proteasome subunit, beta type, 2; PSMB2; testicular tissue protein Li 152
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26445, 29675, 5690
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P40307, P49721, Q9R1P3
Gene Symbols:
PSMB2
Immunogen:
A synthesized peptide derived from human PSMB2(Accession P49721), corresponding to amino acid residues E49-H99.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG