PIPA5102843
MDMX Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5102843-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5102843 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MDMX
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MDM4
Gene Alias
4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17248, 304798, 4194
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O15151, O35618, Q5XIN1
Gene Symbols
MDM4
Immunogen
A synthesized peptide derived from human MDM4(Accession O15151), corresponding to amino acid residues T343-E393.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total MDM4
- The MDM2 protein is the primary regulator of p53 protein stability
- MDMX is an MDM2-related protein that inhibits MDM2-mediated degradation of p53 via distinct associations with MDM2
- The gene that encodes MDMX (also designated MDM4) is a target for amplification in malignant gliomas
- ARF interacts with MDMX to sequester MDMX within the nucleolus
- This sequestration of MDMX by ARF results in an increase in p53 transactivation
- In addition, expression of MDMX can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation
- Like MDM2, MDMX also binds p73 and stabilizes the level of p73
- Therefore, in striking contrast to p53, the half-life of p73 is increased by binding to MDM2.
Compare Similar Items
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Antigen: MDMX
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MDM4
Gene Alias: 4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17248, 304798, 4194
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O15151, O35618, Q5XIN1
Gene Symbols: MDM4
Immunogen: A synthesized peptide derived from human MDM4(Accession O15151), corresponding to amino acid residues T343-E393.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MDMX
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MDM4
Gene Alias:
4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17248, 304798, 4194
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O15151, O35618, Q5XIN1
Gene Symbols:
MDM4
Immunogen:
A synthesized peptide derived from human MDM4(Accession O15151), corresponding to amino acid residues T343-E393.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TRPM2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TRPM2
Gene Alias: 9830168K16Rik; C79133; EC 3.6.1.13; EREG 1; EREG1; Estrogen-responsive element-associated gene 1 protein; KNP 3; KNP3; Long transient receptor potential channel 2; LTRPC 2; LTRPC2; LTrpC-2; MGC133383; NUDT9H; NUDT9L1; null; transient receptor potential cation channel subfamily M member 2; transient receptor potential cation channel, subfamily M, member 2; transient receptor potential channel 7; Transient receptor potential melastatin 2; transient receptor potential melastatin family 2; transient receptor protein 7; Trp7; TRPC 7; TRPC7; TRPM 2; Trpm2; Trpm2-predicted; Trrp7
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 28240, 294329, 7226
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: E9PTA2, O94759, Q91YD4
Gene Symbols: TRPM2
Immunogen: A synthesized peptide derived from human TRPM2(Accession O94759), corresponding to amino acid residues I1405-V1455.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TRPM2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TRPM2
Gene Alias:
9830168K16Rik; C79133; EC 3.6.1.13; EREG 1; EREG1; Estrogen-responsive element-associated gene 1 protein; KNP 3; KNP3; Long transient receptor potential channel 2; LTRPC 2; LTRPC2; LTrpC-2; MGC133383; NUDT9H; NUDT9L1; null; transient receptor potential cation channel subfamily M member 2; transient receptor potential cation channel, subfamily M, member 2; transient receptor potential channel 7; Transient receptor potential melastatin 2; transient receptor potential melastatin family 2; transient receptor protein 7; Trp7; TRPC 7; TRPC7; TRPM 2; Trpm2; Trpm2-predicted; Trrp7
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
28240, 294329, 7226
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
E9PTA2, O94759, Q91YD4
Gene Symbols:
TRPM2
Immunogen:
A synthesized peptide derived from human TRPM2(Accession O94759), corresponding to amino acid residues I1405-V1455.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: IRS2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IRS2
Gene Alias: 4PS; insulin receptor substrate 2; Irs2; IRS-2; tyrosine kinase substrate
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29376, 384783, 8660
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P81122, Q9Y4H2
Gene Symbols: IRS2
Immunogen: A synthesized peptide derived from human IRS2(Accession Q9Y4H2), corresponding to amino acid residues G1078-D1128.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IRS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IRS2
Gene Alias:
4PS; insulin receptor substrate 2; Irs2; IRS-2; tyrosine kinase substrate
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29376, 384783, 8660
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P81122, Q9Y4H2
Gene Symbols:
IRS2
Immunogen:
A synthesized peptide derived from human IRS2(Accession Q9Y4H2), corresponding to amino acid residues G1078-D1128.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SMC3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMC3
Gene Alias: Bam; Bamacan; basement membrane chondroitin sulfate proteoglycan; basement membrane-associated chondroitin proteoglycan; BMH; CDLS3; chondroitin sulfate proteoglycan 6; chondroitin sulfate proteoglycan 6 (bamacan); chromosome segregation protein SmcD; Chromosome-associated polypeptide; cspg6; HCAP; im:7142991; mad member-interacting protein 1; Mmip1; SMC protein 3; Smc3; SMC-3; SMC3 protein; SMC3L1; SmcD; structural maintenace of chromosomes 3; structural maintenance of chromosomes 3; structural maintenance of chromosomes protein 3; structural maintenance of chromosomes protein 3-like protein; wu:fb22e01; wu:fc30d07
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13006, 9126
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9CW03, Q9UQE7
Gene Symbols: SMC3
Immunogen: A synthesized peptide derived from human SMC3(Accession Q9UQE7), corresponding to amino acid residues F1040-V1090.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SMC3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMC3
Gene Alias:
Bam; Bamacan; basement membrane chondroitin sulfate proteoglycan; basement membrane-associated chondroitin proteoglycan; BMH; CDLS3; chondroitin sulfate proteoglycan 6; chondroitin sulfate proteoglycan 6 (bamacan); chromosome segregation protein SmcD; Chromosome-associated polypeptide; cspg6; HCAP; im:7142991; mad member-interacting protein 1; Mmip1; SMC protein 3; Smc3; SMC-3; SMC3 protein; SMC3L1; SmcD; structural maintenace of chromosomes 3; structural maintenance of chromosomes 3; structural maintenance of chromosomes protein 3; structural maintenance of chromosomes protein 3-like protein; wu:fb22e01; wu:fc30d07
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13006, 9126
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9CW03, Q9UQE7
Gene Symbols:
SMC3
Immunogen:
A synthesized peptide derived from human SMC3(Accession Q9UQE7), corresponding to amino acid residues F1040-V1090.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG