PIPA5102859

Phospho-ErbB3 (Tyr1289) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5102859-Each-of-1 In Stock ₹ 45,047.34

PIPA5102859 - Each of 1

₹ 45,047.34

In Stock

Quantity

1

Base Price: ₹ 45,047.34

GST (18%): ₹ 8,108.521

Total Price: ₹ 53,155.861

Antigen

Phospho-ErbB3 (Tyr1289)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ERBB3

Gene Alias

avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13867, 2065, 29496

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P21860, Q61526, Q62799

Gene Symbols

ERBB3

Immunogen

A synthesized peptide derived from human ERBB3(Accession P21860), corresponding to amino acid residues around phosphorylated Tyr1289.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of ERBB3 only when phosphorylated at Tyr1289
  • ErbB3 (c-erbB-3/HER-3) is a member of the type I family of growth factor receptors and binds to ligands in the heregulin family
  • ErbB3 is over-expressed in a variety of tumors in the prostate, bladder, breast, stomach, pancreas, and colon
  • Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents
  • The ErbB3 gene is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6
  • 2kb mRNA which is translated into a 160/180 kDa glycoprotein
  • The ErbB3 gene encodes a transmembrane receptor tyrosine kinase due to alternative splicing and forms heterodimers with other EGF receptor family members that have kinase activity
  • Heterodimerization leads to the activation of pathways that lead to cell proliferation or differentiation
  • Alternate transcriptional splice variants encoding different isoforms of ErbB3 have been characterized
  • One ErbB3 isoform lacks the intermembrane region, is secreted outside the cell, and acts to modulate the activity of the membrane-bound form
  • Additional splice variants have also been reported, but they have not been thoroughly characterized.

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Show Difference

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PIPA5102859

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Antigen:
Phospho-ErbB3 (Tyr1289)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB3

Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13867, 2065, 29496

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P21860, Q61526, Q62799

Gene Symbols:
ERBB3

Immunogen:
A synthesized peptide derived from human ERBB3(Accession P21860), corresponding to amino acid residues around phosphorylated Tyr1289.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5102861

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Antigen:
ASIP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ASIP

Gene Alias:
agouti signaling protein; agouti signaling protein, nonagouti homolog; agouti switch protein; Agouti-signaling protein; AGSW; AGTI; AGTIL; ASIP; ASP; nonagouti homolog; SHEP9

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
434

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P42127

Gene Symbols:
ASIP

Immunogen:
A synthesized peptide derived from human ASIP(Accession P42127), corresponding to amino acid residues K81-N131.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5102862

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Antigen:
CARD11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CARD11

Gene Alias:
0610008L17Rik; 2410011D02Rik; bcl10-interacting maguk protein 3; BENTA; BIMP3; Card11; CARD-containing MAGUK protein 1; Carma 1; CARMA1; caspase recruitment domain family member 11; caspase recruitment domain family, member 11; caspase recruitment domain-containing protein 11; IMD11; LOC100363332; MGC133069; PPBL

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84433

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9BXL7

Gene Symbols:
CARD11

Immunogen:
A synthesized peptide derived from human CARD11(Accession Q9BXL7), corresponding to amino acid residues E626-L676.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5102863

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Antigen:
Jagged2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Jag2

Gene Alias:
D12Ggc2e; HJ2; JAG2; jagged 2; Jagged2; mJagged2-1; protein jagged-2; SER2; Serh; sm; syndactylism

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16450, 29147, 3714

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P97607, Q9QYE5, Q9Y219

Gene Symbols:
Jag2

Immunogen:
A synthesized peptide derived from human JAG2(Accession Q9Y219), corresponding to amino acid residues N354-V404.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG