PIPA5102871

IL-15 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5102871-Each-of-1 In Stock ₹ 45,731.82

PIPA5102871 - Each of 1

₹ 45,731.82

In Stock

Quantity

1

Base Price: ₹ 45,731.82

GST (18%): ₹ 8,231.728

Total Price: ₹ 53,963.548

Antigen

IL-15

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL15

Gene Alias

AI503618; il 15; Il15; IL-15; ILN; Interleukin; interleukin 15; Interleukin15; interleukin-15; MGC9721; M-IL-15

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16168, 3600

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P40933, P48346

Gene Symbols

IL15

Immunogen

A synthesized peptide derived from human IL15(Accession P40933), corresponding to amino acid residues S102-V152.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total IL15
  • IL-15 (Interleukin 15 ) is a cytokine that regulates T and natural killer cell activation and proliferation
  • IL-15 and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity
  • The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2
  • IL-15 induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6
  • In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis
  • IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules
  • As such, IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases
  • Further, IL-15 is a widely expressed pro-inflammatory cytokine and has been shown to play a role in several inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary inflammatory diseases
  • Emerging data suggest that IL-15 may serve as a good therapeutic target, as there appears to be a beneficial effect of IL-15 neutralization in models of psoriasis and diabetes.

Compare Similar Items

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Thermo Scientific

PIPA5102871

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Antigen:
IL-15

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL15

Gene Alias:
AI503618; il 15; Il15; IL-15; ILN; Interleukin; interleukin 15; Interleukin15; interleukin-15; MGC9721; M-IL-15

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16168, 3600

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P40933, P48346

Gene Symbols:
IL15

Immunogen:
A synthesized peptide derived from human IL15(Accession P40933), corresponding to amino acid residues S102-V152.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5102872

--


Antigen:
INSRR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Insrr

Gene Alias:
Insrr; insulin receptor related receptor; insulin receptor-related protein; Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain; insulin receptor-related receptor; IRR; IR-related receptor; Sirr

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23920, 3645

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P14616, Q9WTL4

Gene Symbols:
Insrr

Immunogen:
A synthesized peptide derived from human INSRR(Accession P14616), corresponding to amino acid residues P215-G265.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5102873

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Antigen:
B-myc

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Bmyc

Gene Alias:
2900002K07Rik; avian myelocytomatosis viral (v-myc) related oncogene; AW060705; Bmyc; B-myc; Bmyc protein (AA 1-178); brain expressed myelocytomatosis oncogene; Mycb; Protein B-Myc; transforming protein B-Myc

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107771, 311807

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P15063, Q6P8Z1

Gene Symbols:
Bmyc

Immunogen:
A synthesized peptide derived from mouse Mycb(Accession Q6P8Z1), corresponding to amino acid residues A73-L93.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5102874

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Antigen:
CENPA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cenpa

Gene Alias:
CenH3; CENP A; CENPA; CENP-A; Centromere autoantigen A; centromere protein A; centromere protein A, 17kDa; centromere-specific histone; ggCENP-A; histone H3-like centromeric protein A; RGD1563607

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1058

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P49450

Gene Symbols:
Cenpa

Immunogen:
A synthesized peptide derived from human CENPA(Accession P49450), corresponding to amino acid residues M1-P31.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG