PIPA5102937

AP2S1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102937-Each-of-1 In Stock ₹ 44,705.10

PIPA5102937 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

AP2S1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AP2S1

Gene Alias

adapter-related protein complex 2 sigma subunit; adapter-related protein complex 2 subunit sigma; adaptor protein complex AP-2 subunit sigma; adaptor related protein complex 2 sigma 1 subunit; adaptor-related protein complex 2 sigma 1 subunit; adaptor-related protein complex 2 subunit sigma; adaptor-related protein complex 2, sigma 1 subunit; AI043088; Ap17; AP17-DELTA; AP-2 complex subunit sigma; AP2S1; Claps2; Clathrin assembly protein 2 sigma small chain; clathrin assembly protein 2 small chain; clathrin coat assembly protein AP17; Clathrin coat-associated protein AP17; clathrin-associated protein 17; clathrin-associated/assembly/adaptor protein, small 2 (17kD); FBH3; FBHOk; HA2 17 kDa subunit; HHC3; Plasma membrane adaptor AP-2 17 kDa protein; Sigma2-adaptin; sigma-adaptin 3b

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1175

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P53680

Gene Symbols

AP2S1

Immunogen

A synthesized peptide derived from human AP2S1(Accession P53680), corresponding to amino acid residues M1-V39.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total AP2S1
  • Component of the adaptor protein complex 2 (AP-2)
  • Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways
  • Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation
  • AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome
  • The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components
  • Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation
  • AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis
  • AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface
  • AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules
  • AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway
  • The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif
  • May also play a role in extracellular calcium homeostasis.

Compare Similar Items

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Thermo Scientific

PIPA5102937

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Antigen:
AP2S1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AP2S1

Gene Alias:
adapter-related protein complex 2 sigma subunit; adapter-related protein complex 2 subunit sigma; adaptor protein complex AP-2 subunit sigma; adaptor related protein complex 2 sigma 1 subunit; adaptor-related protein complex 2 sigma 1 subunit; adaptor-related protein complex 2 subunit sigma; adaptor-related protein complex 2, sigma 1 subunit; AI043088; Ap17; AP17-DELTA; AP-2 complex subunit sigma; AP2S1; Claps2; Clathrin assembly protein 2 sigma small chain; clathrin assembly protein 2 small chain; clathrin coat assembly protein AP17; Clathrin coat-associated protein AP17; clathrin-associated protein 17; clathrin-associated/assembly/adaptor protein, small 2 (17kD); FBH3; FBHOk; HA2 17 kDa subunit; HHC3; Plasma membrane adaptor AP-2 17 kDa protein; Sigma2-adaptin; sigma-adaptin 3b

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1175

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P53680

Gene Symbols:
AP2S1

Immunogen:
A synthesized peptide derived from human AP2S1(Accession P53680), corresponding to amino acid residues M1-V39.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102939

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Antigen:
H3F3A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H3-3A

Gene Alias:
H3 histone, family 3A; H3.3A; H3.3B; H3/a; H3-3A; H3-3B; H3F3; H3F3A; H3F3B; Histone 3; Histone H3.3; PP781

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3020

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P84243

Gene Symbols:
H3-3A

Immunogen:
A synthesized peptide derived from human H3F3A, H3F3B(Accession P84243), corresponding to amino acid residues T7-K57.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5102941

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Antigen:
Lysozyme

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LYZ

Gene Alias:
1,4-beta-N-acetylmuramidase C; 1700038F02Rik; 4-beta-N-acetylmuramidase C; AI326280; Allergen Gal d IV; bA534G20.1; c-type lysozyme; dystrophin; egg white lysozyme; Gal d 4; KAAG648; LYC2; Lys; Lysm; lysozyme; lysozyme (renal amyloidosis); lysozyme 1; lysozyme 2; lysozyme C; Lysozyme C type M; lysozyme C type P; Lysozyme C, spleen isozyme; lysozyme C-1; Lysozyme C-2; lysozyme C-3; lysozyme d1; lysozyme F1; lysozyme like 1; lysozyme-like 1; lysozyme-like protein 1; lysozyme-like protein 2; Lysz; LYZ; Lyz1; Lyz2; LYZC; LYZD1; LYZF1; LYZL1; Lyzs; Lzm; Lzm-s1; Lzp; Lzp-s; P lysozyme structural; PRO1278; renal amyloidosis; RGD1559869; unnamed protein product; UNQ648/PRO1278

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4069

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P61626

Gene Symbols:
LYZ

Immunogen:
A synthesized peptide derived from human LYZ(Accession P61626), corresponding to amino acid residues L33-C83.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5102942

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Antigen:
HLF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLF

Gene Alias:
E230015K02Rik; hepatic leukemia factor; HLF; HLF transcription factor, PAR bZIP family member; HLF, PAR bZIP transcription factor; LOC690286; PAR bZIP transcription factor; similar to hepatic leukemia factor

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
217082, 3131

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q16534, Q8BW74

Gene Symbols:
HLF

Immunogen:
A synthesized peptide derived from human HLF(Accession Q16534), corresponding to amino acid residues T73-V123.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG