PIPA5102953

BRCC3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102953-Each-of-1 In Stock ₹ 44,705.10

PIPA5102953 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

BRCC3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BRCC3

Gene Alias

6.1A protein; BRCA1/BRCA2-containing complex subunit 3; BRCA1/BRCA2-containing complex subunit 36; BRCA1/BRCA2-containing complex, subunit 3; BRCA1-A complex subunit BRCC36; Brcc3; BRCC36; BRISC complex subunit BRCC36; C6.1A; CXorf53; lys-63-specific deubiquitinase BRCC36; RP11-143H17.2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

210766, 316794, 79184

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

B2RYM5, P46736, P46737

Gene Symbols

BRCC3

Immunogen

A synthesized peptide derived from human BRCC3(Accession P46736), corresponding to amino acid residues A63-R113.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5103509

--

Img

Thermo Scientific

PIPA5103763

--

Img

Thermo Scientific

PIPA5103761

--

Img

Thermo Scientific

PIPA5103668

--

Img

Thermo Scientific

PIPA5103447

--

Img

Thermo Scientific

PIPA5103771

--

Img

Thermo Scientific

PIPA5103664

--

Img

Thermo Scientific

PIPA5102724

--

Description

  • Antibody detects endogenous levels of total BRCC3
  • Together with the breast and ovarian predisposition proteins BRCA1 and BRCA2 and RAD51 and BRCC45, BRCC36 forms a holoenzyme complex that possesses a ubiquitin E3 ligase activity
  • Aberrant levels of BRCC36 were detected in sporadic breast tumors and depletion of either BRCC36 or BRCC45 by siRNA resulted in increased sensitivity to ionizing radiation and defects in the G2/M checkpoint, indicating that BRCC36 acts to enhance cellular survival following DNA damage
  • Recent experiments have shown that BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation, suggesting that BRCC36 may be an important target in the treatment of radiation-resistant breast tumors
  • At least two isoforms of BRCC36 are known to exist.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5102953

--


Antigen:
BRCC3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BRCC3

Gene Alias:
6.1A protein; BRCA1/BRCA2-containing complex subunit 3; BRCA1/BRCA2-containing complex subunit 36; BRCA1/BRCA2-containing complex, subunit 3; BRCA1-A complex subunit BRCC36; Brcc3; BRCC36; BRISC complex subunit BRCC36; C6.1A; CXorf53; lys-63-specific deubiquitinase BRCC36; RP11-143H17.2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
210766, 316794, 79184

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
B2RYM5, P46736, P46737

Gene Symbols:
BRCC3

Immunogen:
A synthesized peptide derived from human BRCC3(Accession P46736), corresponding to amino acid residues A63-R113.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102954

--


Antigen:
EHD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EHD1

Gene Alias:
AA409636; CDABP0131; EH domain containing 1; EH domain-containing protein 1; Ehd1; EH-domain containing 1; H-PAST; HPAST1; mPAST1; PAST; PAST homolog 1; PAST1; RGD1306960; RME-1; testilin

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10938, 13660, 293692

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q641Z6, Q9H4M9, Q9WVK4

Gene Symbols:
EHD1

Immunogen:
A synthesized peptide derived from human EHD1(Accession Q9H4M9), corresponding to amino acid residues F422-V472.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102956

--


Antigen:
GluR4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gria4

Gene Alias:
AMPA-selective glutamate receptor 4, GluA4, GLUR4, Glur-4, GLUR4C, Gluralpha4, GLURD, GluR-D, glutamate ionotropic receptor AMPA type subunit 4, glutamate receptor, glutamate receptor 4, glutamate receptor channel alpha 4, glutamate receptor ionotropic, AMPA 4, glutamate receptor, ionotrophic, AMPA 4, glutamate receptor, ionotropic, AMPA 4, glutamate receptor, ionotropic, AMPA4 (alpha 4), Gria4, spike wave 1, spkw1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14802, 2893, 29629

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P19493, P48058, Q9Z2W8

Gene Symbols:
Gria4

Immunogen:
A synthesized peptide derived from human GRIA4(Accession P48058), corresponding to amino acid residues T260-E310.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102957

--


Antigen:
RRAGA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RRAGA

Gene Alias:
1300010C19Rik; Adenovirus E3 14.7 kDa-interacting protein 1; adenovirus E3-14.7K interacting protein 1; AI255374; FIP1; FIP-1; Rag A; RAGA; Ras related GTP binding A; Ras-related GTP binding A; ras-related GTP-binding protein A; Ras-related GTP-binding protein ragA; RGD:619804}; rraga; rraga {ECO:0000312

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10670, 117044, 68441

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q63486, Q7L523, Q80X95

Gene Symbols:
RRAGA

Immunogen:
A synthesized peptide derived from human RRAGA(Accession Q7L523), corresponding to amino acid residues S277-R313.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG