PIPA5103035

COPS8 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103035-Each-of-1 In Stock ₹ 44,705.10

PIPA5103035 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

COPS8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cops8

Gene Alias

9430009J09Rik; AA408242; COP9; COP9 (constitutive photomorphogenic) homolog, subunit 8; COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana); COP9 constitutive photomorphogenic homolog subunit 8; COP9 homolog; COP9 signalosome complex subunit 8; COP9 signalosome subunit 8; COPS8; Csn8; hCOP9; JAB1-containing signalosome subunit 8; SGN8; signalosome subunit 8

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

108679, 10920, 363283

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q6P4Z9, Q8VBV7, Q99627

Gene Symbols

Cops8

Immunogen

A synthesized peptide derived from human COPS8(Accession Q99627), corresponding to amino acid residues V36-F86.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total COPS8
  • COPS8 is a COP9 signalosome (CSN), which is an evolutionarily conserved protein complex of the eight subunits that interacts with deubiquitinating enzymes and protein kinases and is highly homologous to the lid sub-complex of 26S proteasome
  • The CSN complex is an essential regulator of the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-complexes such as SCF, CSA or DDB2
  • It is also involved in phosphorylation of p53, c-jun/JUN, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases
  • CSN8 encodes the smallest and the least conserved but first identified subunit of CSN
  • Recent studies show CSN8 is essential for Drosophila development and is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence.

Compare Similar Items

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Thermo Scientific

PIPA5103035

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Antigen:
COPS8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cops8

Gene Alias:
9430009J09Rik; AA408242; COP9; COP9 (constitutive photomorphogenic) homolog, subunit 8; COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana); COP9 constitutive photomorphogenic homolog subunit 8; COP9 homolog; COP9 signalosome complex subunit 8; COP9 signalosome subunit 8; COPS8; Csn8; hCOP9; JAB1-containing signalosome subunit 8; SGN8; signalosome subunit 8

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
108679, 10920, 363283

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6P4Z9, Q8VBV7, Q99627

Gene Symbols:
Cops8

Immunogen:
A synthesized peptide derived from human COPS8(Accession Q99627), corresponding to amino acid residues V36-F86.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5103036

--


Antigen:
TRAM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRAM2

Gene Alias:
C330003D03Rik; KIAA0057; LOC100361830; tram2; TRAM-like protein; Translocating chain-associated membrane protein 2; translocating chain-associating membrane protein 2; translocation associated membrane protein 2; wu:fb20c11; wu:fi23a12; zgc:111902; zgc:55869; zgc:76937

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100361830, 170829, 9697

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15035, Q924Z5

Gene Symbols:
TRAM2

Immunogen:
A synthesized peptide derived from human TRAM2(Accession Q15035), corresponding to amino acid residues R340-P370.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5103037

--


Antigen:
UBE2M

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBE2M

Gene Alias:
2510040H03Rik; EGK_11185; hUbc12; NEDD8 carrier protein; NEDD8 protein ligase; NEDD8-conjugating enzyme Ubc12; UBC12; UBC12 homolog, yeast; UBC-RS2; Ube2m; ubiquitin C, related sequence 2; ubiquitin carrier protein M; ubiquitin conjugating enzyme E2 M; ubiquitin conjugating enzyme E2M; Ubiquitin-conjugating enzyme E2 M; ubiquitin-conjugating enzyme E2M; ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast); ubiquitin-protein ligase M; yeast UBC12 homolog

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22192, 361509, 9040

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P61081, P61082

Gene Symbols:
UBE2M

Immunogen:
A synthesized peptide derived from human UBE2M(Accession P61081), corresponding to amino acid residues S24-G74.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5103040

--


Antigen:
OS9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OS9

Gene Alias:
4632413K17Rik; amplified in osteosarcoma; amplified in osteosarcoma 9; AU022351; endoplasmic reticulum lectin 2; ERLEC2; erlectin 2; OS9; Os-9; OS9 endoplasmic reticulum lectin; OS9, endoplasmic reticulum lectin; osteosarcoma amplified 9; osteosarcoma amplified 9, endoplasmic reticulum associated protein; osteosarcoma amplified 9, endoplasmic reticulum lectin; protein OS-9

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10956, 216440

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13438, Q8K2C7

Gene Symbols:
OS9

Immunogen:
A synthesized peptide derived from human OS9(Accession Q13438), corresponding to amino acid residues F152-I202.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG