PIPA5103127

DIO3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5103127-Each-of-1 In Stock ₹ 44,705.10

PIPA5103127 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DIO3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DIO3

Gene Alias

5DIII; D3; deiodinase, iodothyronine type III; deiodinase, iodothyronine, type 3; deiodinase, iodothyronine, type III; Dio3; DIOIII; I79_015795; iodothyronine deiodinase 3; iodothyronine deiodinase, placental type; Itdi3; LOW QUALITY PROTEIN: thyroxine 5-deiodinase; thyroxine 5-deiodinase; thyroxine deiodinase; thyroxine deiodinase type III (selenoprotein); TXDI3; Type 3 DI; type 3 iodothyronine selenodeiodinase; type III iodothyronine deiodinase; type-III 5' deiodinase; type-III 5'-deiodinase

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

107585, 1735, 29475

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P49897, P55073, Q91ZI8

Gene Symbols

DIO3

Immunogen

A synthesized peptide derived from human DIO3(Accession P55073), corresponding to amino acid residues V117-V141.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total DIO3
  • DIO3 belongs to the iodothyronine deiodinase family
  • It catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively
  • This enzyme is highly expressed in the pregnant uterus, placenta, fetal and neonatal tissues, suggesting that it plays an essential role in the regulation of thyroid hormone inactivation during embryological development
  • This protein contains a selenocysteine (Sec) residue, which is essential for efficient enzyme activity
  • The selenocysteine is encoded by the UGA codon, which normally signals translation termination
  • The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5103127

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Antigen:
DIO3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DIO3

Gene Alias:
5DIII; D3; deiodinase, iodothyronine type III; deiodinase, iodothyronine, type 3; deiodinase, iodothyronine, type III; Dio3; DIOIII; I79_015795; iodothyronine deiodinase 3; iodothyronine deiodinase, placental type; Itdi3; LOW QUALITY PROTEIN: thyroxine 5-deiodinase; thyroxine 5-deiodinase; thyroxine deiodinase; thyroxine deiodinase type III (selenoprotein); TXDI3; Type 3 DI; type 3 iodothyronine selenodeiodinase; type III iodothyronine deiodinase; type-III 5' deiodinase; type-III 5'-deiodinase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107585, 1735, 29475

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P49897, P55073, Q91ZI8

Gene Symbols:
DIO3

Immunogen:
A synthesized peptide derived from human DIO3(Accession P55073), corresponding to amino acid residues V117-V141.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103128

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Antigen:
DP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TFDP2

Gene Alias:
1110029I05Rik; A330080J22Rik; BTPS2; DP2; DP2.5; DP3; DP-3; E2F dimerization partner 2; GS; Tcfdp2; TFDP2; transcription factor Dp 2; transcription factor Dp-2; transcription factor Dp-2 (E2F dimerization partner 2); Unknown (protein for MGC:133813)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
211586, 300947, 7029

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q14188, Q64163

Gene Symbols:
TFDP2

Immunogen:
A synthesized peptide derived from human TFDP2(Accession Q14188), corresponding to amino acid residues A95-R145.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103130

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Antigen:
SCNN1G

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCNN1G

Gene Alias:
[g]ENaC; amiloride sensitive sodium channel gamma1 subunit; amiloride-sensitive epithelial sodium channel gamma subunit; amiloride-sensitive sodium channel gamma-subunit; amiloride-sensitive sodium channel subunit gamma; BESC3; ENaC; ENaC gamma; ENaC gamma subunit; ENaCG; ENaCgamma; epithelial Na(+) channel subunit gamma; epithelial sodium channel gamma subunit; Gamma ENaC; Gamma NaCH; gamma-ENaC; Gamma-NaCH; nonvoltage-gated sodium channel 1 subunit gamma; PHA 1; PHA1; SCNEG; SCNN 1G; Scnn1g; sodium channe epithelial 1 gamma subunit; sodium channel epithelial 1 gamma subunit; Sodium channel nonvoltage-gated 1 gamma (epithelial); sodium channel, non voltage gated 1 gamma subunit; sodium channel, nonvoltage-gated 1 gamma; sodium channel, nonvoltage-gated 1, gamma; Sodium channel, nonvoltage-gated 1, gamma (epithelial); sodium channel, non-voltage-gated 1, gamma subunit; sodium channel, nonvoltage-gated, type I, gamma

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20278, 24768, 6340

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P37091, P51170, Q9WU39

Gene Symbols:
SCNN1G

Immunogen:
A synthesized peptide derived from human SCNN1G(Accession P51170), corresponding to amino acid residues H610-L649.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103131

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Antigen:
ENDOG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ENDOG

Gene Alias:
endo G; Endog; endonuclease G; endonuclease G, mitochondrial; mitochondrial endonuclease G

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13804, 2021, 362100

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O08600, Q14249

Gene Symbols:
ENDOG

Immunogen:
A synthesized peptide derived from human ENDOG(Accession Q14249), corresponding to amino acid residues L36-D86.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG