PIPA5103148

SCN8A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103148-Each-of-1 In Stock ₹ 44,705.10

PIPA5103148 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SCN8A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Scn8a

Gene Alias

AI853486; ataxia 3; C630029C19Rik; CERIII; CIAT; dmu; EIEE13; hNa6/Scn8a voltage-gated sodium channel; MED; mnd2; mnd-2; Na+ channel; naCh6; Nav1.6; Nbna1; nmf2; nmf335; nmf58; nur14; peripheral nerve protein type 4; PN4; SCN8A; Scn8a (PN4); seal; Sodium channel 6; sodium channel protein type 8 subunit alpha; Sodium channel protein type VIII subunit alpha; sodium channel voltage-gated type VIII alpha polypeptide; sodium channel, voltage gated, type VIII alpha subunit; sodium channel, voltage gated, type VIII, alpha subunit; sodium channel, voltage-gated, type 8, alpha polypeptide; sodium channel, voltage-gated, type 8, alpha subunit; sodium channel, voltage-gated, type VIII, alpha; sodium channel, voltage-gated, type VIII, alpha polypeptide; sodium voltage-gated channel alpha subunit 8; voltage-gated sodium channel subunit alpha Nav1.6; voltage-gated sodium channel type VIII alpha protein

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20273, 29710, 6334

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O88420, Q9UQD0, Q9WTU3

Gene Symbols

Scn8a

Immunogen

A synthesized peptide derived from human SCN8A(Accession Q9UQD0), corresponding to amino acid residues Y1038-N1088.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total Nav1.6/SCN8A
  • The sodium channel protein type 8 subunit alpha (Na+ CP type VIII alpha ) is a multi-pass, transmembrane protein that mediates the sodium ion permeability of excitable membranes
  • The three glycoproteins that comprise the voltage-gated sodium channel proteins include a pore-forming alpha subunit, a noncovalently associated beta1 subunit and a disulfide-linked beta2 subunit
  • The two beta subunits regulate the level of channel expression, modulate gating and function as cell adhesion molecules for cellular aggregation and cytoskeleton interaction
  • The alpha subunits of sodium channels type I and III are predominantly expressed in neuronal cell bodies and proximal processes, while type II alpha subunits are more abundant along axons
  • Sodium channels are important for rapid signal transduction but also play a significant role in neuronal development
  • Defects of the SCN8A gene have exhibited detrimental effects on the growth of secondary motoneurons
  • Loss of SCN8A expression will result in progressive paralysis and early death.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5103148

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Antigen:
SCN8A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Scn8a

Gene Alias:
AI853486; ataxia 3; C630029C19Rik; CERIII; CIAT; dmu; EIEE13; hNa6/Scn8a voltage-gated sodium channel; MED; mnd2; mnd-2; Na+ channel; naCh6; Nav1.6; Nbna1; nmf2; nmf335; nmf58; nur14; peripheral nerve protein type 4; PN4; SCN8A; Scn8a (PN4); seal; Sodium channel 6; sodium channel protein type 8 subunit alpha; Sodium channel protein type VIII subunit alpha; sodium channel voltage-gated type VIII alpha polypeptide; sodium channel, voltage gated, type VIII alpha subunit; sodium channel, voltage gated, type VIII, alpha subunit; sodium channel, voltage-gated, type 8, alpha polypeptide; sodium channel, voltage-gated, type 8, alpha subunit; sodium channel, voltage-gated, type VIII, alpha; sodium channel, voltage-gated, type VIII, alpha polypeptide; sodium voltage-gated channel alpha subunit 8; voltage-gated sodium channel subunit alpha Nav1.6; voltage-gated sodium channel type VIII alpha protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20273, 29710, 6334

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O88420, Q9UQD0, Q9WTU3

Gene Symbols:
Scn8a

Immunogen:
A synthesized peptide derived from human SCN8A(Accession Q9UQD0), corresponding to amino acid residues Y1038-N1088.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103149

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Antigen:
TSPAN9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSPAN9

Gene Alias:
6720474K14Rik; 9430079M16Rik; AU018597; NET5; NET-5; new EST tetraspan 5; PP1057; RGD1304740; tetraspan NET-5; tetraspanin 9; tetraspanin-9; transmembrane 4 superfamily member tetraspan NET-5; Tspan9; tspan-9

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10867, 109246

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75954, Q8BJU2

Gene Symbols:
TSPAN9

Immunogen:
A synthesized peptide derived from human TSPAN9(Accession O75954), corresponding to amino acid residues A143-K193.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103150

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Antigen:
NTN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NTN1

Gene Alias:
AI561871; BC019633; Epididymis tissue protein Li 131P; HGNC:8029; netrin 1; netrin 1, mouse, homolog of; Netrin1; netrin-1; Ntn1; NTN1L

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114523, 18208, 9423

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O09118, O95631, Q924Z9

Gene Symbols:
NTN1

Immunogen:
A synthesized peptide derived from human NTN1(Accession O95631), corresponding to amino acid residues A572-A604.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103151

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Antigen:
NMDAR2C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRIN2C

Gene Alias:
GluN2C; GluRepsilon3; glutamate [NMDA] receptor subunit epsilon-3; glutamate ionotropic receptor NMDA type subunit 2C; glutamate receptor; glutamate receptor ionotropic, NMDA 2C; glutamate receptor ionotropic, NMDA 2C; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2C; glutamate receptor, ionotropic, NMDA2C; glutamate receptor, ionotropic, NMDA2C (epsilon 3); glutamate receptor, ionotropic, N-methyl D-aspartate 2C; Grin2c; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2C; NMDA glutamate receptor; NMDAR2C; N-methyl D-aspartate receptor subtype 2C; N-methyl-D-aspartate receptor subunit 2C; NR2; NR2C

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2905

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q14957

Gene Symbols:
GRIN2C

Immunogen:
A synthesized peptide derived from human GRIN2C(Accession Q14957), corresponding to amino acid residues H402-L452.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG