PIPA5103187

CYB561D2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103187-Each-of-1 In Stock ₹ 44,705.10

PIPA5103187 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CYB561D2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CYB561D2

Gene Alias

101F6; 101F6 protein; AW049681; CYB561D2; cytochrome b-561 domain containing 2; cytochrome b561 domain-containing protein 2; cytochrome b561 family member D2; cytochrome b561 family, member D2; gene for 101F6 protein; LUCA12.2; OTTHUMP0000021067; OTTHUMP00000210675; OTTHUMP00000210676; Putative tumor suppressor protein 101F6; Transmembrane ascorbate ferrireductase; Tsp10; tumor suppressor, region 10; XXcos-LUCA11.4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11068, 363137

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O14569, Q641Y1

Gene Symbols

CYB561D2

Immunogen

A synthesized peptide derived from human CYB561D2(Accession O14569), corresponding to amino acid residues Q122-A172.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5103468

--

Img

Thermo Scientific

PIPA5102862

--

Img

Thermo Scientific

PIPA5103190

--

Img

Thermo Scientific

PIPA5103188

--

Img

Thermo Scientific

PIPA5102091

--

Img

Thermo Scientific

PIPA5102397

--

Img

Thermo Scientific

PIPA5102321

--

Img

Thermo Scientific

PIPA5103076

--

Description

  • Antibody detects endogenous levels of total C56D2
  • CYB561D2 (Cytochrome b561 domain-containing protein 2), also known as putative tumor suppressor protein 101F6, is a 222 amino acid highly hydrophobic protein that contains six membrane spanning domains
  • Localized to endosomes and endoplasmic reticulum of the perinuclear region, CYB561D2 contains 2 heme-binding sites, through which it reduces ferric ions
  • CYB561D2 is ubiquitously expressed, with highest levels in lung, liver and kidney
  • Though expression of CYB561D2 is abundant in normal lung bronchial epithileal cells, CYB561D2 is absent in most lung cancers
  • The gene encoding CYB561D2 maps to human chromosome 3p21.3, a region that is prone to genetic alterations and is associated with frequent and early allele loss in many human cancers
  • Exogenous expression of CYB561D2 leads to the induction of caspase-independent apoptotic and autophagic pathways, resulting in the synergistic killing of tumor cells
  • This suggests an important role for CYB561D2 as a therapeutic intervention in cancer treatment.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5103187

--


Antigen:
CYB561D2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CYB561D2

Gene Alias:
101F6; 101F6 protein; AW049681; CYB561D2; cytochrome b-561 domain containing 2; cytochrome b561 domain-containing protein 2; cytochrome b561 family member D2; cytochrome b561 family, member D2; gene for 101F6 protein; LUCA12.2; OTTHUMP0000021067; OTTHUMP00000210675; OTTHUMP00000210676; Putative tumor suppressor protein 101F6; Transmembrane ascorbate ferrireductase; Tsp10; tumor suppressor, region 10; XXcos-LUCA11.4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11068, 363137

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O14569, Q641Y1

Gene Symbols:
CYB561D2

Immunogen:
A synthesized peptide derived from human CYB561D2(Accession O14569), corresponding to amino acid residues Q122-A172.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103188

--


Antigen:
CARD10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CARD10

Gene Alias:
AI449026; Bcl10 binding protein and activator of NFKB; bcl10-interacting MAGUK protein 1; Bimp1; Card10; CARD-containing MAGUK 3 protein; CARD-containing MAGUK protein 3; Carma 3; Carma3; caspase recruitment domain family member 10; caspase recruitment domain family, member 10; caspase recruitment domain-containing protein 10

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
105844, 29775

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P58660, Q9BWT7

Gene Symbols:
CARD10

Immunogen:
A synthesized peptide derived from human CARD10(Accession Q9BWT7), corresponding to amino acid residues T68-Q118.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103190

--


Antigen:
CD2BP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD2BP2

Gene Alias:
1500011B02Rik; 2410024K20Rik; AW048183; CD2 (cytoplasmic tail) binding protein 2; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 cytoplasmic tail binding protein 2; CD2 tail-binding protein 2; CD2BP2; FWP010; KIAA1178; LIN1; PPP1R59; protein phosphatase 1, regulatory subunit 59; Snu40; U5 snRNP 52K protein; U5-52K

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10421, 70233

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O95400, Q9CWK3

Gene Symbols:
CD2BP2

Immunogen:
A synthesized peptide derived from human CD2BP2(Accession O95400), corresponding to amino acid residues D104-A154.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103193

--


Antigen:
TPX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tpx2

Gene Alias:
2610005B21Rik; C20orf1; C20orf2; Differentially expressed in cancerous and non-cancerous lung cells 2; differentially expressed in lung cells; DIL2; DIL-2; FLS353; GD: HCA519; GD:C20orf1; HCA519; HCTP4; Hepatocellular carcinoma-associated antigen 519; hepatocellular carcinoma-associated antigen 90; p100; preferentially expressed in colorectal cancer; protein fls353; REPP86; restricted expression proliferation associated protein 100; restricted expression proliferation-associated protein 100; Targeting protein for Xklp2; TPX 2; Tpx2; TPX2 microtubule nucleation factor; TPX2, microtubule nucleation factor; TPX2, microtubule-associated; TPX2, microtubule-associated protein homolog; TPX2, microtubule-associated protein homolog (Xenopus laevis); TPX2, microtubule-associated, homolog

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22974, 311546, 72119

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
A2APB8, Q9ULW0

Gene Symbols:
Tpx2

Immunogen:
A synthesized peptide derived from human TPX2(Accession Q9ULW0), corresponding to amino acid residues K685-V735.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG