PIPA5103259

GTF3C3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5103259-Each-of-1 In Stock ₹ 44,705.10

PIPA5103259 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

GTF3C3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GTF3C3

Gene Alias

AL022818; general transcription factor 3C polypeptide 3; general transcription factor IIIC subunit 3; general transcription factor IIIC, polypeptide 3; general transcription factor IIIC, polypeptide 3, 102kDa; GTF3C3; im:7136784; LOC553318 protein; TF3C3; TF3C-gamma; TFIIIC 102 kDa subunit; TFIIIC102; TFiiiC2-102; TFIIICgamma; Transcription factor IIIC 102 kDa subunit; Transcription factor IIIC subunit gamma; transcription factor IIIC-gamma subunit

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9330, 98488

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9Y5Q9

Gene Symbols

GTF3C3

Immunogen

A synthesized peptide derived from human GTF3C3(Accession Q9Y5Q9), corresponding to amino acid residues E27-G77.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total TF3C3
  • RNA polymerase (pol) III synthesizes tRNA, 5s rRNA, 7SL RNA and U6 snRNA and is overexpressed in many transformed cell lines and tumors in vivo, since cells must duplicate its protein components before division
  • Therefore, in order to maintain rapid growth, cells must produce a high level of Pol III transcribed RNA, which requires the presence of the TFIIIB and TFIIIC2 transcription factor complexes
  • The TFIIIC2 complex is composed of five subunits, TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, that are overexpressed in adenovirus transformed cells as well as in malignant cells in vivo, such as ovarian carcinomas
  • TFIIIC2 recruits RNA pol III and TFIIIB to promoter elements and may be a key component in the deregulation of malignant cells
  • The TFIIIB complex includes the TATA-binding protein (TBP), TFIIB-related factor 1 (BRF1) and TFIIIB, the expression of which are also upregulated in transformed cells
  • In many carcinomas, the tumor suppressors retinoblastoma (RB) and p53 are inactivated, which affects their ability to bind and inactivate the function of TFIIIB.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5103259

--


Antigen:
GTF3C3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GTF3C3

Gene Alias:
AL022818; general transcription factor 3C polypeptide 3; general transcription factor IIIC subunit 3; general transcription factor IIIC, polypeptide 3; general transcription factor IIIC, polypeptide 3, 102kDa; GTF3C3; im:7136784; LOC553318 protein; TF3C3; TF3C-gamma; TFIIIC 102 kDa subunit; TFIIIC102; TFiiiC2-102; TFIIICgamma; Transcription factor IIIC 102 kDa subunit; Transcription factor IIIC subunit gamma; transcription factor IIIC-gamma subunit

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9330, 98488

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9Y5Q9

Gene Symbols:
GTF3C3

Immunogen:
A synthesized peptide derived from human GTF3C3(Accession Q9Y5Q9), corresponding to amino acid residues E27-G77.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103260

--


Antigen:
GTF3C4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GTF3C4

Gene Alias:
5330400C03; AI426938; AU014771; AU017413; general transcription factor 3C 4; general transcription factor 3C polypeptide 4; general transcription factor IIIC 4; general transcription factor IIIC subunit 4; general transcription factor IIIC, polypeptide 4; general transcription factor IIIC, polypeptide 4, 90kDa; Gtf3c4; KAT12; TF3C-delta; TFIII90; TFIIIC 90 kDa subunit; TFIIIC290; TFIIIC90; TFIIICDELTA; transcription factor IIIC 90 kDa subunit; Transcription factor IIIC subunit delta

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
269252, 9329

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8BMQ2, Q9UKN8

Gene Symbols:
GTF3C4

Immunogen:
A synthesized peptide derived from human GTF3C4(Accession Q9UKN8), corresponding to amino acid residues D148-N198.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5103262

--


Antigen:
p53DINP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TP53INP1

Gene Alias:
2700057G22Rik; p53-dependent damage-inducible nuclear protein 1; p53DINP1; p53-inducible p53DINP1; Sip; SIP18; SIP27; Stinp; stress induced protein; stress-induced protein; TEAP; thymus expressed acidic protein; thymus-expressed acidic protein; TP53DINP1; TP53INP1; TP53INP1A; TP53INP1B; transformation related protein 53 inducible nuclear protein 1; Trp53inp1; tumor protein p53 inducible nuclear protein 1; tumor protein p53-inducible nuclear protein 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
60599, 94241

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q96A56, Q9QXE4

Gene Symbols:
TP53INP1, Trp53inp1

Immunogen:
A synthesized peptide derived from human TP53INP1(Accession Q96A56), corresponding to amino acid residues G166-R216.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5103264

--


Antigen:
ZNF23

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF23

Gene Alias:
B230354B21Rik; KOX16; kruppel-like zinc finger factor X31; Zfp23; Zfp612; zinc finger protein 23; zinc finger protein 23 (KOX 16); zinc finger protein 32; zinc finger protein 359; Zinc finger protein 612; Zinc finger protein KOX16; ZNF23; ZNF359; ZNF612

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7571

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P17027

Gene Symbols:
ZNF23

Immunogen:
A synthesized peptide derived from human ZNF23(Accession P17027), corresponding to amino acid residues R166-R216.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG