PIPA5103271

Phospho-MEKK1 (Thr1400) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103271-Each-of-1 In Stock ₹ 43,592.82

PIPA5103271 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

Phospho-MEKK1 (Thr1400)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP3K1

Gene Alias

MAP/ERK kinase kinase 1; MAP3K1; MAPK/ERK kinase kinase 1; MAPKKK1; MEK kinase 1; MEKK; MEKK 1; Mekk1; mitogen activated protein kinase kinase kinase 1; mitogen-activated protein kinase kinase kinase 1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; si:rp71-80a19.2; SRXY6

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

116667, 26401, 4214

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P53349, Q13233, Q62925

Gene Symbols

MAP3K1

Immunogen

A synthesized peptide derived from human MAP3K1(Accession Q13233), corresponding to amino acid residues around phosphorylated Thr1400.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of MEKK1 only when phosphorylated at Thr1400, which site historically referenced as Thr1402
  • Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK)
  • MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK
  • The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells
  • MEKK1 can phosphorylate and activate MAPKK 1 and MAPKK 2 (MEK1/MEK2) which leads to phosphorylation of MAP kinases
  • It is also a highly efficient activator of the JNK cascade
  • The protein contains a putative 1 RING-type zinc finger and 1 SWIM-type zinc finger.

Compare Similar Items

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Img

Thermo Scientific

PIPA5103271

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Antigen:
Phospho-MEKK1 (Thr1400)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K1

Gene Alias:
MAP/ERK kinase kinase 1; MAP3K1; MAPK/ERK kinase kinase 1; MAPKKK1; MEK kinase 1; MEKK; MEKK 1; Mekk1; mitogen activated protein kinase kinase kinase 1; mitogen-activated protein kinase kinase kinase 1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; si:rp71-80a19.2; SRXY6

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116667, 26401, 4214

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P53349, Q13233, Q62925

Gene Symbols:
MAP3K1

Immunogen:
A synthesized peptide derived from human MAP3K1(Accession Q13233), corresponding to amino acid residues around phosphorylated Thr1400.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103272

--


Antigen:
Phospho-OXSR1 (Thr185)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Oxsr1

Gene Alias:
2210022N24Rik; 2810422B09Rik; AI462649; AW209236; C6orf182; CEP57R; KIAA1101; mKIAA1101; Osr1; OTTHUMP00000209062; oxidative stress responsive 1; oxidative stress responsive kinase 1; oxidative stress-responsive 1 protein; oxidative-stress responsive 1; OXSR1; Serine/threonine-protein kinase OSR1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
108737, 316064, 9943

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O95747, Q6P9R2

Gene Symbols:
Oxsr1

Immunogen:
A synthesized peptide derived from human OXSR1(Accession O95747), corresponding to amino acid residues around phosphorylated Thr185.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103273

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Antigen:
Phospho-RRN3 (Ser649)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RRN3

Gene Alias:
A-270G1.2; AL023001; E130302O19Rik; R75565; RGD1305001; RNA polymerase I-specific transcription initiation factor RRN3; Rrn3; RRN3 homolog, RNA polymerase I transcription factor; RRN3 RNA polymerase I transcription factor homolog; RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae); RRN3 RNA polymerase I transcription factor homolog (yeast); Tif1a; TIF-1A; TIFIA; TIF-IA; Transcription initiation factor IA; transcription initiation factor TIF-IA

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
106298, 304714, 54700

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
B2RS91, Q9NYV6

Gene Symbols:
RRN3

Immunogen:
A synthesized peptide derived from human RRN3(Accession Q9NYV6), corresponding to amino acid residues around phosphorylated Ser649.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5103274

--


Antigen:
MT-ND3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MT-ND3

Gene Alias:
1.6.5.3; mitochondrially encoded NADH dehydrogenase 3; Mtnd3; mt-Nd3; NADH dehydrogenase subunit 3; NADH3; NADH-ubiquinone oxidoreductase chain 3; ND3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17718, 26199, 4537

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P03897, P03899, P05506

Gene Symbols:
MT-ND3

Immunogen:
A synthesized peptide derived from human MT-ND3(Accession P03897), corresponding to amino acid residues L15-F65.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG