PIPA5103363
APOBEC3C Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103363-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5103363 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
APOBEC3C
Classification
Polyclonal
Conjugate
Unconjugated
Gene
APOBEC3C
Gene Alias
A3C; APOBEC1L; APOBEC1-like; APOBEC3C; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; MGC19485; PBI; Phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27350
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q9NRW3
Gene Symbols
APOBEC3C
Immunogen
A synthesized peptide derived from human APOBEC3C(Accession Q9NRW3), corresponding to amino acid residues N159-Q190.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total APOBEC3C
- APOBEC (apolipoprotein B mRNA editing enzyme, catalytic) proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA
- The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22
- Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA
- Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses
- Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome
- Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication
- This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
Compare Similar Items
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Antigen: APOBEC3C
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APOBEC3C
Gene Alias: A3C; APOBEC1L; APOBEC1-like; APOBEC3C; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; MGC19485; PBI; Phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27350
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9NRW3
Gene Symbols: APOBEC3C
Immunogen: A synthesized peptide derived from human APOBEC3C(Accession Q9NRW3), corresponding to amino acid residues N159-Q190.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
APOBEC3C
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APOBEC3C
Gene Alias:
A3C; APOBEC1L; APOBEC1-like; APOBEC3C; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; MGC19485; PBI; Phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27350
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9NRW3
Gene Symbols:
APOBEC3C
Immunogen:
A synthesized peptide derived from human APOBEC3C(Accession Q9NRW3), corresponding to amino acid residues N159-Q190.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MBIP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MBIP
Gene Alias: 4933408E06Rik; BM-015; MAP3K12 binding inhibitory protein 1; MAP3K12-binding inhibitory protein 1; MAPK upstream kinase-binding inhibitory protein; MBIP; MUK-binding inhibitory protein; Unknown (protein for MGC:143421)
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51562
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9NS73
Gene Symbols: MBIP
Immunogen: A synthesized peptide derived from human MBIP(Accession Q9NS73), corresponding to amino acid residues R215-G265.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MBIP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MBIP
Gene Alias:
4933408E06Rik; BM-015; MAP3K12 binding inhibitory protein 1; MAP3K12-binding inhibitory protein 1; MAPK upstream kinase-binding inhibitory protein; MBIP; MUK-binding inhibitory protein; Unknown (protein for MGC:143421)
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51562
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9NS73
Gene Symbols:
MBIP
Immunogen:
A synthesized peptide derived from human MBIP(Accession Q9NS73), corresponding to amino acid residues R215-G265.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: IBTK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IBTK
Gene Alias: Bruton agammaglobulinemia tyrosine kinase inhibitor; BTBD26; BTK-binding protein; BTKI; IBTK; Inhibitor of Bruton tyrosine kinase; inhibitor of Bruton's tyrosine kinase-alpha; inhibitor of Bruton's tyrosine kinase-beta; inhibitor of Bruton's tyrosine kinase-gamma; KIAA1417; RP1-93K22.1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 25998
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9P2D0
Gene Symbols: IBTK
Immunogen: A synthesized peptide derived from human IBTK(Accession Q9P2D0), corresponding to amino acid residues V1224-T1274.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
IBTK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IBTK
Gene Alias:
Bruton agammaglobulinemia tyrosine kinase inhibitor; BTBD26; BTK-binding protein; BTKI; IBTK; Inhibitor of Bruton tyrosine kinase; inhibitor of Bruton's tyrosine kinase-alpha; inhibitor of Bruton's tyrosine kinase-beta; inhibitor of Bruton's tyrosine kinase-gamma; KIAA1417; RP1-93K22.1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
25998
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9P2D0
Gene Symbols:
IBTK
Immunogen:
A synthesized peptide derived from human IBTK(Accession Q9P2D0), corresponding to amino acid residues V1224-T1274.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: RBPJL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RBPJL
Gene Alias: RBP-J kappa-like; RBPJL; RBPL; RBP-L; RBPSUHL; recombination signal binding protein for immunoglobulin kappa J region like; recombination signal binding protein for immunoglobulin kappa J region-like; recombining binding protein suppressor of hairless-like protein; SUHL; Transcription factor RBP-L
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11317, 19668
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O08674, Q9UBG7
Gene Symbols: RBPJL
Immunogen: A synthesized peptide derived from human RBPJL(Accession Q9UBG7), corresponding to amino acid residues L173-S223.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
RBPJL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RBPJL
Gene Alias:
RBP-J kappa-like; RBPJL; RBPL; RBP-L; RBPSUHL; recombination signal binding protein for immunoglobulin kappa J region like; recombination signal binding protein for immunoglobulin kappa J region-like; recombining binding protein suppressor of hairless-like protein; SUHL; Transcription factor RBP-L
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11317, 19668
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O08674, Q9UBG7
Gene Symbols:
RBPJL
Immunogen:
A synthesized peptide derived from human RBPJL(Accession Q9UBG7), corresponding to amino acid residues L173-S223.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG