PIPA5103500

ALKBH2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5103500-Each-of-1 In Stock ₹ 44,705.10

PIPA5103500 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ALKBH2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ALKBH2

Gene Alias

2OG-Fe(II) oxy DC1; 9530023G02; Abh2; AlkB homolog 2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase; alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 2; alkB, alkylation repair homolog 2 (E. coli); ALKBH2; Alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; mABH2; oxy DC1; RGD1306377

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

121642, 231642

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q6NS38, Q6P6J4

Gene Symbols

ALKBH2

Immunogen

A synthesized peptide derived from human ALKBH2(Accession Q6NS38), corresponding to amino acid residues I141-A191.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total ALKBH2
  • The E
  • coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA; ALKBH2 and ALKBH3 are mammalian homologs of AlkB that catalyze the removal of 1-methyladenine and 3-methylcytosine, modifications that left unchecked could lead to cancerous cells
  • Mutations in both ALKBH2 and ALKBH3 have been observed in pediatric brain tumors indicating that these proteins are important in the prevention of cancer formation
  • Like the histone demethylase JMJD1A, ALKBH2 is a non-heme iron enzyme that is inhibited by Nickel ions, suggesting that inhibition of ALKBH2 by Nickel ions may play a role in the development of cancer
  • Conversely, ALKBH2 mRNA and protein levels are increased glioma cells following Photofrin-mediated photodynamic therapy, an adjuvant therapy in cancer treatment, suggesting that down-regulating ALKBH2 expression in cancer cells may enhance the anti-cancer effectiveness of this treatment.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5103500

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Antigen:
ALKBH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALKBH2

Gene Alias:
2OG-Fe(II) oxy DC1; 9530023G02; Abh2; AlkB homolog 2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase; alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 2; alkB, alkylation repair homolog 2 (E. coli); ALKBH2; Alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; mABH2; oxy DC1; RGD1306377

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
121642, 231642

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6NS38, Q6P6J4

Gene Symbols:
ALKBH2

Immunogen:
A synthesized peptide derived from human ALKBH2(Accession Q6NS38), corresponding to amino acid residues I141-A191.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5103502

--


Antigen:
BCL6B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCL6B

Gene Alias:
B cell CLL/lymphoma 6, member B; B cell CLL/lymphoma 6B; BAZF; B-cell CLL/lymphoma 6 member B protein; B-cell CLL/lymphoma 6, member B; B-cell CLL/lymphoma 6, member B (zinc finger protein); B-cell CLL/lymphoma 6B; Bcl6-associated zinc finger protein; Bcl6b; BCL6B transcription repressor; BCL6B, transcription repressor; LOW QUALITY PROTEIN: B-cell CLL/lymphoma 6 member B protein; RGD1563179; ZBTB28; zinc finger protein 62; ZNF62

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12029, 255877

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O88282, Q8N143

Gene Symbols:
BCL6B

Immunogen:
A synthesized peptide derived from human BCL6B(Accession Q8N143), corresponding to amino acid residues L145-K195.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103503

--


Antigen:
GEMIN8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GEMIN8

Gene Alias:
B130034M20Rik; B930082C09Rik; BC023488; Fam51a1; family with sequence similarity 51, member A1; family with sequence similarity 51, member A1 homolog; gem (nuclear organelle) associated protein 8; gem nuclear organelle associated protein 8; gem-associated protein 8; GEMIN8; Gemin-8; Protein FAM51A1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
237221, 363462, 54960

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8BHE1, Q9NWZ8

Gene Symbols:
GEMIN8

Immunogen:
A synthesized peptide derived from human GEMIN8(Accession Q9NWZ8), corresponding to amino acid residues R203-F242.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103505

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Antigen:
SP5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SP5

Gene Alias:
SP5; Sp5 transcription factor; trans-acting transcription factor 5; transcription factor Sp5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
389058, 64406

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6BEB4, Q9JHX2

Gene Symbols:
SP5

Immunogen:
A synthesized peptide derived from human SP5(Accession Q6BEB4), corresponding to amino acid residues T260-T310.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG