PIPA5103519

HSD3B1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103519-Each-of-1 In Stock ₹ 44,705.10

PIPA5103519 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

HSD3B1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HSD3B1

Gene Alias

3 beta-hydroxysteroid dehydrogenase 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3BETAHSD; 3-beta-HSD; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid dehydrogenase; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; 3-beta-hydroxysteroid 3-dehydrogenase; 3BH; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase; HGNC:5217; HSD3B; Hsd3b1; HSDB3; HSDB3A; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; hydroxy-delta-MAY-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; hydroxysteroid dehydrogenase-1, delta<5>-3-beta; I; Progesterone reductase; SDR11E1; short chain dehydrogenase/reductase family 11E, member 1; steroid Delta-isomerase; Trophoblast antigen FDO161G; unnamed protein product

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3283, 360348

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P14060, P22071

Gene Symbols

HSD3B1

Immunogen

A synthesized peptide derived from human HSD3B1(Accession P14060), corresponding to amino acid residues A129-T179.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total HSD3B1
  • Amyloid beta peptide (Abeta/Beta-amyloid) is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimer's disease
  • Abeta peptide is 40-43 amino acids long and generated from the beta-amyloid precursor protein (beta APP) in a two-step process
  • The first step involves cleavage of the extracellular, amino-terminal domain of beta APP
  • Protein cleavage is performed by an aspartyl protease, beta-secretase (BACE) which is synthesized as a propeptide and must be modified to the mature and active form by the prohormone convertase, furin
  • Beta APP cleavage by the mature form of BACE results in the cellular secretion of a segment of beta APP, and a membrane-bound remnant
  • The remnant protein is processed by another protease, gamma-secretase
  • Gamma-secretase cleaves an intra-membrane site in the carboxyl-terminal domain of beta APP, thus generating the amyloid beta peptide
  • Gamma-secretase is believed to be a multi-subunit complex containing presenilin-1 and 2 as central components
  • The transmembrane glycoprotein, nicastrin, is associated with presinilins and has been found to bind to the carboxyl-terminus of beta APP and helps to modulate the production of the amyloid beta peptide
  • Abeta is an extracellular filamentous protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles
  • Alzheimer's disease, the most common cause of senile dementia, is characterized by abnormal filamentous protein deposits in the brain
  • Beta amyloid deposits are also detected in Lewy body dementia, Down's syndrome, amyloidosis (Dutch type), cerebroarterial amyloidosis (cerebral amyloid angiopathy) and in the Guam Parkinson-Dementia complex.

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Show Difference

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PIPA5103519

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Antigen:
HSD3B1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HSD3B1

Gene Alias:
3 beta-hydroxysteroid dehydrogenase 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3BETAHSD; 3-beta-HSD; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid dehydrogenase; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; 3-beta-hydroxysteroid 3-dehydrogenase; 3BH; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase; HGNC:5217; HSD3B; Hsd3b1; HSDB3; HSDB3A; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; hydroxy-delta-MAY-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; hydroxysteroid dehydrogenase-1, delta<5>-3-beta; I; Progesterone reductase; SDR11E1; short chain dehydrogenase/reductase family 11E, member 1; steroid Delta-isomerase; Trophoblast antigen FDO161G; unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3283, 360348

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P14060, P22071

Gene Symbols:
HSD3B1

Immunogen:
A synthesized peptide derived from human HSD3B1(Accession P14060), corresponding to amino acid residues A129-T179.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5103520

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Antigen:
MRPL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MRPL1

Gene Alias:
2410002L03Rik; 39S ribosomal protein L1, mitochondrial; 5830418D04Rik; AI462572; BM022; BM-022; L1mt; Mitochondrial large ribosomal subunit protein uL1m; mitochondrial ribosomal protein L1; Mrpl1; MRP-L1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
65008

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9BYD6

Gene Symbols:
MRPL1

Immunogen:
A synthesized peptide derived from human MRPL1(Accession Q9BYD6), corresponding to amino acid residues E202-F252.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5103521

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Antigen:
MRPL17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MRPL17

Gene Alias:
39S ribosomal protein L17, mitochondrial; L17mt; LIP2; LYST-interacting protein 2; LYST-interacting protein LIP2; Mitochondrial large ribosomal subunit protein bL17m; mitochondrial ribosomal protein L17; MRPL17; MRP-L17; MRP-L26; ribosomal protein, mitochondrial, L26; RPL17L; RPML26

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27397, 63875

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9D8P4, Q9NRX2

Gene Symbols:
MRPL17

Immunogen:
A synthesized peptide derived from human MRPL17(Accession Q9NRX2), corresponding to amino acid residues A76-K126.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5103522

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Antigen:
MRPL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MRPL2

Gene Alias:
39S ribosomal protein L2, mitochondrial; CGI-22; L2mt; Mitochondrial large ribosomal subunit protein uL2m; mitochondrial ribosomal protein L2; MRP-L14; MRPL2; MRP-L2; ribosomal protein, mitochondrial, L14; Rpml14

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27398, 301240, 51069

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q498T4, Q5T653, Q9D773

Gene Symbols:
MRPL2

Immunogen:
A synthesized peptide derived from human MRPL2(Accession Q5T653), corresponding to amino acid residues A242-M292.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG